Protein Alignment SmydA-1 and Smyd3

DIOPT Version :10

• Sequence 1: NP_610944.1
• Gene: SmydA-1 / 36581
• FlyBaseID: FBgn0033917
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: NP_001020933.1
• Gene: Smyd3 / 498295
• RGDID: 1562635
• Length: 428
• Species: Rattus norvegicus
• Alignment Length: 486
• Identity: 112/486 - (23%)
• Similarity: 174/486 - (35%)
• Gaps: 155/486 - (31%)

  Fly    52 GRHLVATRTIKPYEIVLKEAPLV----RGPAQISAPVCLGCLNGIEAEDHIECEQCG-WPLCGPE 111
            |..|.|...::|.|::.:..||.    :|...:   ||..||.|  .|..:.|.||. ...|..:
  Rat    15 GNGLRAVAPLRPGELLFRSDPLAYTVSKGSRGV---VCDRCLLG--KEKLMRCSQCRIAKYCSAK 74

  Fly   112 C--KSLDEHKAECGLTKD---RGQKVNVQEFGGPHPLYTCLSTVRCLLIGETS-TEKASKFQDLE 170
            |  |:..:||.||...|.   |....:|:..|         ..|..|:.|:.| :||...|.|||
  Rat    75 CQKKAWPDHKRECKCLKSCKPRYPPDSVRLLG---------RVVVKLMDGKPSESEKLYSFYDLE 130

  Fly   171 S-----LESTRRGSNQ--------WKADLVSIGQFIPKFFKTQKFTEEEIMKAVGALQINGHEVP 222
            |     .|..:.|..|        .:.::....|..|.|         ::.:|...:..|...:.
  Rat   131 SNISKLTEDKKEGLRQLAMTFQHFMREEIQDASQLPPSF---------DLFEAFAKVICNSFTIC 186

  Fly   223 TTDPSHVAV--FYTASFTENSCLPNLAKSFNKNGHCILWAPREIKKNAHLSICYSDAMWGTADRQ 285
            ..:...|.|  :.:.|...:||.||.:..|| ..|.:|.|.|||:....|:|||.|.:..:.:|:
  Rat   187 NAEMQEVGVGLYPSMSLLNHSCDPNCSIVFN-GPHLLLRAVREIEAGEELTICYLDMLMTSEERR 250

  Fly   286 RHLMQTKLFKCACERCVDVTELDTNYSAIKCEDRQCGGLMLPTKADEWNGSWRCRECHKQVQKHY 350
            :.|.....|:|.|.||             :.:|:.         ||...|.   .:..|:||
  Rat   251 KQLRDQYCFECDCIRC-------------QTQDKD---------ADMLTGD---EQIWKEVQ--- 287

  Fly   351 VERILERAGKDIQSMEKIAENGLKYLKHYEKWLPPQHFHMSEIKILLVQLLAKDQKELMVIPDDR 415
                        :|::||.|     ||.:.||         |..:.|.|.:.....|.  :||
  Rat   288 ------------ESLKKIEE-----LKAHWKW---------EQVLALCQAIINSNSER--LPD-- 322

  Fly   416 LLLKLNFARELVELYE-KLTPCEVRTLGTLCFELHSAIAEQTRRVALETSLSPKDRLEESLFYVD 479
                       :.:|: |:..|.:    ..|..|                    ..|||:|||..
  Rat   323 -----------INIYQLKVLDCAM----DACINL--------------------GMLEEALFYAM 352

  Fly   480 KCVNYLKYESDIFIEG-------HVLKQAKI 503
            :.:...:    ||..|       .|:|..|:
  Rat   353 RTMEPYR----IFFPGSHPVRGVQVMKVGKL 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-1	NP_610944.1	zf-MYND	4..40	CDD:460312
		SET_SMYD	<217..301	CDD:380997	26/85 (31%)
Smyd3	NP_001020933.1	SET_SMYD3	5..268	CDD:380980	74/289 (26%)
		zf-MYND	49..87	CDD:460312	13/39 (33%)