DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SmydA-1 and Smyd5

DIOPT Version :9

Sequence 1:	NP_610944.1	Gene:	SmydA-1 / 36581	FlyBaseID:	FBgn0033917	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_001101340.1	Gene:	Smyd5 / 312503	RGDID:	1309153	Length:	417	Species:	Rattus norvegicus

Alignment Length:	394	Identity:	75/394 - (19%)
Similarity:	120/394 - (30%)	Gaps:	156/394 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 GRHLVATRTIKPYEIVLKEAPLVRGP----AQISAPVCLGCLNGIE-AED--------------- 96
            |:.|.||:.|:..|.:..|.|||...    |......|..||..:| ||:
  Rat    33 GKGLFATQLIRKGETIFIERPLVASQFLWNALYRYRACDHCLRALEKAEENAQRLTGKPGQVLPH 97

  Fly    97 ----------HIECEQCGWPLCGPECK---SLDEHKAEC-GLTKDRGQKVNVQEFGGPHPL---- 143
                      |..|.:|....|..||:   :...|:..| |.::|..:          |||
  Rat    98 PELCSVRKDLHQNCPRCQVTYCSAECRLAAAEQYHQILCPGPSQDDPR----------HPLNKLQ 152

  Fly   144 -------YTCLSTVRCLLIGETSTEKASKFQD-----------------------------LESL 172
                   |...:....|:....:|.|.:|.:|                             ...|
  Rat   153 EAWRSVHYPPETASIMLMARMVATVKQAKDKDHWVRLFSHFCSKTANEEEEIVHKLLGDKFKGQL 217

  Fly   173 ESTRR---------------------------GSN----------QW----------KADLVSIG 190
            |..||                           |:|          ||          ..:...:.
  Rat   218 ELLRRLFTEALYEETLSQWFTPDGFRSLFALVGTNGQGIGTSSLSQWVHACDALELKPQEREQLD 282

  Fly   191 QFIPKFFKTQKFTEEEIMKAVGALQINGHEVPTTDPSHVAVFYTASFTENSCLPNLAKSFNKNGH 255
            .||.:.:|..:....|.:...|:                .:|...|...:||:||...||.:|..
  Rat   283 TFIDQLYKDIEAATGEFLNCEGS----------------GLFVLQSCCNHSCVPNAETSFPENNF 331

  Fly   256 CI-LWAPREIKKNAHLSICYSDAMWGTADRQRH-----LMQTKLFKCACERCVDVTELDTNYSAI 314
            .: :.|..:|:....:.|.|.|..  ..:|.||     |.:..||.|:|.:|:...: |.|.::.
  Rat   332 LLHVTALEDIEPGEEICISYLDCC--QRERSRHSRHKILRENYLFVCSCPKCLAEAD-DPNVTSE 393

  Fly   315 KCED 318
            :.|:
  Rat   394 EEEE 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-1	NP_610944.1	zf-MYND	4..40	CDD:280009
Smyd5	NP_001101340.1	DUF4599	68..144	CDD:292015	16/75 (21%)
Smyd5	NP_001101340.1	SET	<298..351	CDD:214614	14/68 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810