DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SmydA-1 and set-10

DIOPT Version :9

Sequence 1:	NP_610944.1	Gene:	SmydA-1 / 36581	FlyBaseID:	FBgn0033917	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_493620.2	Gene:	set-10 / 185237	WormBaseID:	WBGene00009370	Length:	430	Species:	Caenorhabditis elegans

Alignment Length:	494	Identity:	107/494 - (21%)
Similarity:	173/494 - (35%)	Gaps:	144/494 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 VLKEAPL--VRGPAQISAPVCLGCLNGIEAEDHIE---CEQC-GWPLCGPECKSLDE---HKAEC 122
            |.:|.||  |..| |.|...|..|...|::....|   |:.| ....|..:|:..|.   |:.||
Worm     4 VAREQPLAAVLSP-QFSELYCATCFLEIDSSQETEILTCDDCLAVSYCTLKCQRKDWKSCHQFEC 67

  Fly   123 GLTKDRGQKVNVQEFGGPHPLYTCLSTVRCLLIGETSTEKAS----KFQDLESLESTRRGS---N 180
            .:.:.:|...         |:...:.....:|:...||:..|    ..:|||:.....|.|   |
Worm    68 EILRCQGSST---------PMTLTMKLCIRVLLASRSTQTPSFNGAVLEDLETNYKEFRSSPEHN 123

  Fly   181 QWKADLVSI----GQFI-PKFFKTQK--------------FTEEEIMKAVGA---LQINGHEVPT 223
            |:.:|:::|    ||.| |...:|.|              ...|:.::.:|:   :.:..|....
Worm   124 QFLSDVLTIISSSGQNIFPTSLETNKTIGIICSVLCNSFSIINEKRVEPIGSGLYVGVAKHNHSC 188

  Fly   224 TDPSHVAVFYTASFTENSCLPNLAKSFNKNGHCILWAPREIKKNAHLSICYSDAMWGTADRQRHL 288
            ...||| ||                    .|:.:.....:.:.:..|:|.|...|..|::|::.:
Worm   189 ASTSHV-VF--------------------EGNQVFLRTNQEEYSKELTISYVSRMLPTSERRKTI 232

  Fly   289 MQTKLFKCACERCVDVTELDTNYSAIKCEDRQCGGLMLPTKADEWNGSWRCRECHK------QVQ 347
            .......|.||.|.: .|||....:.||..:.|.|.:        .||..|..|.|      :..
Worm   233 RGVHFLTCQCEMCKN-EELDLIGLSSKCRTKNCTGFV--------KGSGNCSVCEKLAFLPFEQS 288

  Fly   348 KHYVERILERAGKDIQSMEKIAENGLKYLKHYEKWLPPQHFHMSEIKILLVQLLAKDQKELMVIP 412
            .|....:|:           |.||                .|.:. :...||.||..||......
Worm   289 IHSTLNLLD-----------IIEN----------------LHKTN-QFTTVQELAYLQKLRADYQ 325

  Fly   413 DDRLLLKLNFARELVELYEKLTPC--EVRTLGTLCFELHS-------------AIAEQTRRVALE 462
            |  :|.:.|.|  :::|.|::..|  .:..:..|..:|.:             ...|.|||:.:.
Worm   326 D--ILAECNVA--ILQLDEQIAYCSSSLENVNDLDLDLIAGRGSEHFITRLGIGAPEVTRRLYIG 386

  Fly   463 ----TSLSPKDRLEESLFYVDKCVNYLK--YESDIFIEG 495
                :.:||..|..       |.|..:|  .||.|...|
Worm   387 CKCISRISPSKRSV-------KLVKLIKLAIESSIISHG 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-1	NP_610944.1	zf-MYND	4..40	CDD:280009
set-10	NP_493620.2	zf-MYND	23..67	CDD:366792	10/43 (23%)
set-10	NP_493620.2	SET	57..247	CDD:394802	44/219 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D981799at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820