DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SmydA-1 and smyd3

DIOPT Version :9

Sequence 1:	NP_610944.1	Gene:	SmydA-1 / 36581	FlyBaseID:	FBgn0033917	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	XP_031758360.1	Gene:	smyd3 / 100494527	XenbaseID:	XB-GENE-854970	Length:	448	Species:	Xenopus tropicalis

Alignment Length:	411	Identity:	93/411 - (22%)
Similarity:	153/411 - (37%)	Gaps:	83/411 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 CLGCLNGIEAEDHIECEQCGWP-LCGPEC--KSLDEHKAECGLTKDRGQKVNVQEFGGPHPLYTC 146
            |..||:  ..|..:.|.||... .|...|  |:...||.||...  |....||..
Frog    67 CDHCLH--RKEKLLRCSQCKVARYCNSHCQRKAWQGHKRECKCL--RSTLPNVPP---------- 117

  Fly   147 LSTVRCLLIG----------ETSTEKASKFQDL-----ESLESTRRG--------SNQWKADLVS 188
             ::||  |:|          :|::|:.....||     |:.|..:.|        .:..|.::..
Frog   118 -NSVR--LVGKIIFKMLQKPDTASEELYTISDLQSHIKEASEEVKDGLRHLATALQHYLKEEIQE 179

  Fly   189 IGQFIPKFFKTQKFTEEEIMKAVGALQINGHEVPTTDPSHVAVFYTASFTENSCLPNLAKSFNKN 253
            |.|..|.|...:.|.:........:..|:..|:....   |.::.:.|...:||.||....|  .
Frog   180 ISQLPPGFQVLEYFGKVSAKVTCNSFTISDGEMQDVG---VGLYPSMSLLNHSCDPNCVIVF--E 239

  Fly   254 GHCILW-APREIKKNAHLSICYSDAMWGTADRQRHLMQTKLFKCACERCV------DVTELDTNY 311
            |.|:|. ..:||.|...|:|.|.|....|..|:..|.:...|.|.|:||:      |:...|...
Frog   240 GTCLLLRTVKEIPKGEELTISYIDVKMPTQGRRDQLQRQYCFLCDCQRCLLRDKDEDMLAGDAEA 304

  Fly   312 S-AIKCEDRQCGGLMLPTKADEWNGSWRCRECHKQVQKHYVE-------RILE---RAGKDIQSM 365
            | .::....:...|:....|:|     ....|...:.::|:.       :||:   .|..|:...
Frog   305 SREVESSVSRLEELLSQNTAEE-----ALNLCKTLMNRYYLPDKNIYQLKILDCAMDASIDLGLW 364

  Fly   366 EKIAENGLK----YLKHYEKWLPPQHFHMSEI-KILLVQ-LLAKDQKELMVIPDDRLLLKLNFAR 424
            |:....||:    |..:|..:.|.:...:.:: |:...| |.|:..|.|....|   ::|:...|
Frog   365 EEALHFGLRTLEPYSLYYSNYHPVRAVQLMKVGKLQNYQGLFAEAMKTLKQAFD---IMKVTHGR 426

  Fly   425 ---ELVELYEKLTPCEVRTLG 442
               :..:|.|.:..||....|
Frog   427 DHGQTQQLAELMNDCEANMRG 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-1	NP_610944.1	zf-MYND	4..40	CDD:280009
smyd3	XP_031758360.1	SET_SMYD3	24..289	CDD:380980	60/243 (25%)
smyd3	XP_031758360.1	zf-MYND	67..105	CDD:396356	12/39 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D981799at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010