DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SmydA-1 and smyd1

DIOPT Version :9

Sequence 1:	NP_610944.1	Gene:	SmydA-1 / 36581	FlyBaseID:	FBgn0033917	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	XP_012811600.1	Gene:	smyd1 / 100145429	XenbaseID:	XB-GENE-978314	Length:	491	Species:	Xenopus tropicalis

Alignment Length:	419	Identity:	96/419 - (22%)
Similarity:	139/419 - (33%)	Gaps:	121/419 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 KIAHNEQLGRHLVATRTIKPYEIVLKEAPLVRGPA-------QISAPVCLGCLNGIEAEDHIECE 101
            :|..:|..||.|.|.|.....:|:..|      ||       .:|..||..|..  ..|..:.|.
Frog     5 EIFESEGKGRGLRAIRESWAGDIIFAE------PAYSAVVFDNLSHSVCHSCFK--RQEKLLRCG 61

  Fly   102 QCGWP-LCGPEC--KSLDEHKAECGLTKDRGQKVN------------VQEFGGPHPLYTCLSTVR 151
            ||.:. .|...|  :|...||.||...|..|:..|            ::..|..       .|..
Frog    62 QCKFAHYCDRTCQKESWANHKNECVAIKKAGKAPNENIRLAARILWRIEREGSG-------LTEG 119

  Fly   152 CLLIGETSTEKASKFQDLES---LESTRRGSNQWKADLVSIG-QFIPKFFKT---QKFT--EEEI 207
            ||:..:.......||.:.|.   :|..::....|.:.....| |:|...|..   ..||  ::..
Frog   120 CLVSIDDLQNHIDKFDEAEKGLLMEDVQKFLEYWPSQSQQFGMQYISHIFSVISCNGFTLSDQRG 184

  Fly   208 MKAVGALQINGHEVPTTDPSHVAVFYTASFTENSCLPNLAKSFNKNGH------------CILWA 260
            ::|||                |.:|.......:.|.||....||...|            ..|.|
Frog   185 LQAVG----------------VGIFPNLCLANHDCWPNCTVIFNNGNHEAVRSMFHTQMRIELRA 233

  Fly   261 PREIKKNAHLSICYSDAMWGTADRQRHLMQTKLFKCACERCVDVTELDTNYSAI----------- 314
            ..:|.|...|::.|.|.:..|.||:..|.:...|.|.||.|...|: |....|:
Frog   234 LGKINKGEELTVSYVDFLNLTEDRKAQLKKQYYFDCTCEHCTKKTK-DALLLAVKDGEDKPEERV 297

  Fly   315 -------------KCEDRQCGGLMLPTKADEWNGSWR-CRECHKQVQ------KHYVERIL---E 356
                         |.|..:..||        :|...: ||:|.|:.:      ..|:.|||   .
Frog   298 VKEVIQYSKDTMEKIEKARSEGL--------YNDVVKLCRDCLKRQEPIFADTNIYMLRILSIYS 354

  Fly   357 RAGKDIQSMEKIAENGLK----YLKHYEK 381
            .....:|..:..|||..|    |||.|.:
Frog   355 EVLSYLQMFDDAAENAKKMVDGYLKIYHQ 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-1	NP_610944.1	zf-MYND	4..40	CDD:280009
smyd1	XP_012811600.1	zf-MYND	47..85	CDD:280009	11/39 (28%)
smyd1	XP_012811600.1	SET	<189..252	CDD:214614	16/78 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D981799at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010