Protein Alignment Usp20-33 and Usp20

DIOPT Version :10

• Sequence 1: NP_610943.2
• Gene: Usp20-33 / 36580
• FlyBaseID: FBgn0033916
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_083122.1
• Gene: Usp20 / 74270
• MGIID: 1921520
• Length: 916
• Species: Mus musculus
• Alignment Length: 820
• Identity: 324/820 - (39%)
• Similarity: 455/820 - (55%)
• Gaps: 133/820 - (16%)

  Fly    60 DSNASDSEGTDTAKGSGTGLVGLQNIANTCYMNSALQALSNLPPMTHYFINCSDLVEYIAEQSAR 124
            |...|:||..|.   ...||.|::|:.|:||||:|||||||.||:|.:|:.|..||        |
Mouse   128 DEGESESEDDDL---KPRGLTGMKNLGNSCYMNAALQALSNCPPLTQFFLECGGLV--------R 181

  Fly   125 RCKPGGLAKSYRRLMQEIWQDVDDPKEFIAPRGILYGIRTVHPMFRGYQQHDTQEFLRCFMDQLH 189
            ..|...|.|||::|:.|:|.  .....::.|..:.:||:.|:||||||.|.||||||||.|||||
Mouse   182 TDKKPALCKSYQKLISEVWH--KKRPSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLMDQLH 244

  Fly   190 EELTEQVSMLPQTQNQPQYQSLQQQQPSETDDENDDEAAPAS---LSHASES------------- 238
            |||.|     |...........:....|:||:..|.:.:|:.   ||..|.|
Mouse   245 EELKE-----PMVAAVAALTDARDSDSSDTDERRDGDRSPSEDEFLSCDSSSDRGEGDGQGRGGG 304

  Fly   239 ---------------------------------------------EYDTCESSMSERSAEVLLKT 258
                                                         :.||..:|:.|:|.|....:
Mouse   305 SSKAEMELLISDEAGRAISEKERMKDRKFSWGQQRTNSEQVDEDADVDTAMASLDEQSREAQPPS 369

  Fly   259 EYFVTPCRT----------NGSNSGLP-----EGHSVQLQQAP-------------LQHQQKNAS 295
            ....:||:|          :.|....|     |||| :|..:|             |:..|..::
Mouse   370 PRSTSPCQTPEPDNEAHIRSSSRPCSPVHHHHEGHS-KLSSSPPRASPVRMGPSYVLKKAQVPST 433

  Fly   296 SAEQKPIEAARSIISDVFDGKLLSSVQCLTCDRVSTREETFQDLSLPIPNRDFLNVLHQTHSLSV 360
            ...::..::.||:|||||:|.:||.|||||||||||..|||||||||||.::.|..||.....:|
Mouse   434 GGRRRKEQSYRSVISDVFNGSVLSLVQCLTCDRVSTTVETFQDLSLPIPGKEDLAKLHSAIYQNV 498

  Fly   361 QSLNAAETSARTNEGWLSWMWNMLR--------SWIYGPSVTLYDCMASFFSADELKGDNMYSCE 417
            .:...|...:.:::|||:::...:|        ||.:||.|||.||:|:||:|||||||||||||
Mouse   499 PAKPGACGDSYSSQGWLAFIVEYIRRFVVSCTPSWFWGPVVTLEDCLAAFFAADELKGDNMYSCE 563

  Fly   418 RCNKLRTGIKYSRVLTLPEVLCIHLKRFRNDLSYSSKISSDVYFPLEGFDMRPYIHKDCKSEVAI 482
            ||.|||.|:||.:||.|||:||:||||||:::.||.|:||.|.|||||.|:||::.|:|.|:|..
Mouse   564 RCKKLRNGVKYCKVLCLPEILCVHLKRFRHEVMYSFKVSSHVSFPLEGLDLRPFLAKECTSQVTT 628

  Fly   483 YNLSSVICHHGTVGGGHYTCFARNTLNGKWYEFDDQFVTEVSSELVQSCQAYVLFYHKHNPQMKL 547
            |:|.||||||||.|.|||..:.:|.:||:|||||||:||||...:||:.:||||||.|.:.:...
Mouse   629 YDLLSVICHHGTAGSGHYIAYCQNVINGQWYEFDDQYVTEVHETVVQNVEAYVLFYRKSSEEAMR 693

  Fly   548 VRDEAMTLSTSHPLCDSDIQFYITREWLSRLATFSEPGPINNQEMLCPHGGILHSKADVISQIAV 612
            .|.:.::|:....  .|.::||::||||::..||:|||||.|...||.||||..:|...|..:.|
Mouse   694 ERQQVVSLAAMRE--PSLLRFYVSREWLNKFNTFAEPGPITNHTFLCSHGGIPPNKYHYIDDLVV 756

  Fly   613 PISQPLWDYLYRTFGGGPAVNIIFECEICKRAAETLSRRQQYELNEFTKYN-GLQNEFDSTAIYA 676
            .:.|.:|::||..||||||||.::.|.||:...|.|::|::.|::.|.|.| ..|.|.....||.
Mouse   757 ILPQSVWEHLYSRFGGGPAVNHLYVCSICQVEIEALAKRRRVEIDTFIKLNKAFQAEESPAVIYC 821

  Fly   677 IAMPWLRSWQQFSRGKTHKDPGPITNEGIAAPTENGSATVSCVRLGSDYAQLNARLWRFLHNIYG 741
            |:|.|.|.|:.|.:||..:.||||.|..||  ...||..:. ::.|:|..|::...|.:|.::||
Mouse   822 ISMHWFREWEAFVKGKDSEPPGPIDNSRIA--QVKGSGHIQ-LKQGADCGQISEETWTYLSSLYG 883

  Fly   742 GGPEIILRQALSDEDDAEEIEIIDQDDECDDDEDQDLEGE 781
            |||||.:||:::...|.|.:.           .:|.:|.|
Mouse   884 GGPEIAIRQSVAQLPDPESLH-----------GEQKIEAE 912

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp20-33	NP_610943.2	UCH	80..538	CDD:425685	226/554 (41%)
		DUSP	560..643	CDD:197831	39/82 (48%)
		DUSP	667..755	CDD:197831	34/87 (39%)
Usp20	NP_083122.1	zf-UBP	30..90	CDD:460464
		UBP12	<73..688	CDD:227847	236/578 (41%)
		UCH	145..684	CDD:425685	226/554 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	258..420		26/162 (16%)
		DUSP	704..787	CDD:197831	39/84 (46%)
		DUSP	812..896	CDD:197831	34/86 (40%)