Protein Alignment Usp20-33 and Usp11

DIOPT Version :10

• Sequence 1: NP_610943.2
• Gene: Usp20-33 / 36580
• FlyBaseID: FBgn0033916
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_001008861.2
• Gene: Usp11 / 408217
• RGDID: 1303052
• Length: 921
• Species: Rattus norvegicus
• Alignment Length: 681
• Identity: 158/681 - (23%)
• Similarity: 238/681 - (34%)
• Gaps: 210/681 - (30%)

  Fly    78 GLVGLQNIANTCYMNSALQALSNLPPMTHYFINCSDLVEYIAEQSARRCKP----GGLAKSYRRL 138
            |:.||.|:.|||:||||||.|||:|.:|.||:|    ..|:.|.:.|  .|    |.||::|..|
  Rat   255 GICGLTNLGNTCFMNSALQCLSNVPQLTEYFLN----NRYLEELNFR--NPLGMKGELAEAYADL 313

  Fly   139 MQEIWQDVDDPKEFIAPRGILYGIRTVHPMFRGYQQHDTQEFLRCFMDQLHEELT-----EQVSM 198
            :::.|...   ...|.|......:......|.||||||:||.|...:|.|||:|.     |.|.:
  Rat   314 VKQTWSGY---HRSIVPNVFKNKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVEL 375

  Fly   199 LPQTQNQPQYQSLQQQQPSETDDENDDEAAPASLSHASESEYDTCESS----------------- 246
            .    |......|:..|.:..:.:..:::......|........|...
  Rat   376 C----NGAGRPDLEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPL 436

  Fly   247 --MSERSAEVLL-------KTEYFVTPCRTNGSNSGLPEGHSVQLQQAP--------LQHQQKNA 294
              .|.|..||..       |.|.........|:.|.|....|.....||        ..|:....
  Rat   437 PVCSRRVLEVFFVPMDPRRKPEQHRVVVPKKGNISDLCVALSTHTSVAPDKMIVADVFSHRFYKL 501

  Fly   295 SSAEQ--------------------KPIEAAR--------------------------------- 306
            ...|.                    :|:|.:|
  Rat   502 YQLEDPLSGILDRDDIFVYEVTGRIEPVEGSRDDIVVPVYLRERTPSRDYNNSYYGLILFGHPLL 566

  Fly   307 -SIISDVFDGKLLSSVQCLTCDRVSTR--------------------------EETFQDLSLPIP 344
             |:..|.|..:.|.::......|..|:                          ||..:::|.|..
  Rat   567 VSVPRDRFSWEGLYNILMYRLSRYVTKPTSDDDDGDEKGDENEDEDVEDDSSSEEEKEEMSGPTD 631

  Fly   345 NRD----------------------FLNVLH---------QTHSLSVQSLNAAETSART------ 372
            |..                      ..|.||         :....::|::|:..||.||
  Rat   632 NDGTQESEQEQAGTSSGVTGRCPSLLDNSLHTSQWPPRRRRKQLFTLQTVNSNGTSDRTTSPEEA 696

  Fly   373 -NEGWLSWMWN------------------------MLRSWIYGPSVTLYDCMASFFSADELKGDN 412
             .:.:::..|.                        ||:.   .| |.|.:|:..|.:.:.|:.:|
  Rat   697 QTQPYIAMDWEPEMKRRYYDEVEAEGYVKHDCVGYMLKK---NP-VQLKECIKLFTTVETLEKEN 757

  Fly   413 MYSCERCNKLRTGIKYSRVLTLPEVLCIHLKRFRNDLSYSSKISSDVYFPLEGFDMRPYIHKDCK 477
            .:.|..|.:.:...|...:..|||||.||||||........|:.:.|.||:...|...::.|. |
  Rat   758 PWYCSSCKQHQLATKKLDLWMLPEVLIIHLKRFSFSKFSREKLDTLVQFPIRDLDFSEFVIKP-K 821

  Fly   478 SEVA----IYNLSSVICHHGTVGGGHYTCFARNTLNGKWYEFDDQFVTEVSSELVQSCQAYVLFY 538
            :|.|    .|:|.:|..|:|.:..||||.||.|..:|:|:.|||..|:.|:...::|..||||||
  Rat   822 NESAPDLYKYDLIAVSNHYGGMRDGHYTTFACNKDSGQWHYFDDNSVSPVNENQIESKAAYVLFY 886

  Fly   539 HKHN---PQMKLVRDEAMTLSTSHPLCDSDI 566
            .:.:   .|.:....|..|...|....:|||
  Rat   887 QRQDVGRRQSQTASSETPTSPASSSTPNSDI 917

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp20-33	NP_610943.2	UCH	80..538	CDD:425685	148/646 (23%)
		DUSP	560..643	CDD:197831	3/7 (43%)
		DUSP	667..755	CDD:197831
Usp11	NP_001008861.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		UBP12	23..888	CDD:227847	151/650 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	592..697		15/104 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	893..921		7/25 (28%)