Protein Alignment Usp20-33 and usp42

DIOPT Version :10

• Sequence 1: NP_610943.2
• Gene: Usp20-33 / 36580
• FlyBaseID: FBgn0033916
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: XP_005169520.1
• Gene: usp42 / 327528
• ZFINID: ZDB-GENE-030131-5739
• Length: 1168
• Species: Danio rerio
• Alignment Length: 1093
• Identity: 210/1093 - (19%)
• Similarity: 330/1093 - (30%)
• Gaps: 439/1093 - (40%)

  Fly    81 GLQNIANTCYMNSALQALSNLPPMTHYFINCSDLVEYIAEQSARRCKPGGLAKSYRRLMQEIWQD 145
            ||.|:.|||::||.||.|:...|:.:|.         :..:.::.|...|..... .:...|.|.
Zfish   115 GLHNLGNTCFLNSTLQCLTYTAPLANYM---------LTREHSKTCHEPGFCMMC-TMQNHIIQV 169

  Fly   146 VDDPKEFIAPRGILYGIRTVHPMFRGYQQHDTQEFLRCFMDQLHEELTEQVSMLPQTQNQPQYQS 210
            ..:....|.|..:|..::.:...||...|.|..||||..:|.:      |.|.||..:...|.|
Zfish   170 FANSGNVIKPISVLNELKRIGKHFRFGSQEDAHEFLRYTVDAM------QKSCLPGNKLDRQTQ- 227

  Fly   211 LQQQQPSETDDENDDEAAPASLSHASESEYDTCESSMSERSAEVLLKTEYFVTPCRTNGSNSGLP 275
                                                                             
Zfish   228 ----------------------------------------------------------------- 227

  Fly   276 EGHSVQLQQAPLQHQQKNASSAEQKPIEAARSIISDVFDGKLLSSVQCLTCDRVSTREETFQDLS 340
                                         |.:.:..:|.|.|.|.|:||.|..||...:.:.|:|
Zfish   228 -----------------------------ATTFVHQIFGGYLRSRVKCLNCKAVSDTFDPYLDIS 263

  Fly   341 LPIPNRDFLNVLHQTHSLSVQSLNAAETSARTNEGWLSWMWNMLRSWIYGPSVTLYDCMASFFSA 405
            |.|                    ..|:|.::..|                          .|...
Zfish   264 LEI--------------------KTAQTLSKAFE--------------------------QFVKP 282

  Fly   406 DELKGDNMYSCERCNKLRTGIKYSRVLTLPEVLCIHLKRFRNDLSYSSKISSDVYFPLEGFDMRP 470
            ::|.|||.|.|.:|.|:.|..|...|.....||.|.||||.|  ....||:.||.: .|..|:||
Zfish   283 EQLDGDNAYKCSKCKKMVTASKRFTVHRSSNVLTISLKRFTN--FNGGKITKDVRY-AEHLDLRP 344

  Fly   471 YIHKDCKSEVAIYNLSSVICHHG-TVGGGHYTCFARNTLNGKWYEFDDQFVTEVSSELVQSCQAY 534
            ::.:. ..|..||.|.:|:.|.| :...|||.|:.:.: ||:||:.:|..|:......|.:.|||
Zfish   345 FMSQS-HGEPQIYALYAVLVHSGFSCHAGHYYCYIKAS-NGQWYQMNDSSVSLSDIRTVLNQQAY 407

  Fly   535 VLFYHKHNPQMKLVRDEAMTLST--------SHPLCDSDIQFYITREWLSRLATFSEPGPINNQE 591
            :|||.: :|.:|...|.:....|        |.||..:..|:          .|.|..||
Zfish   408 LLFYIR-SPDVKNGGDFSQMNHTPGQSSPRPSIPLKMNGPQY----------TTTSFIGP----- 456

  Fly   592 MLCPH---------------------------GGIL-----HSKADV--------ISQIAVPIS- 615
            .|.||                           ||:.     |:.:..        :..:.:|.|
Zfish   457 QLPPHMLKNSSYVNGNGSSKEYHGGSKPNRNFGGVTKIGPSHTSSSASASSSSLPVRSMGIPDSS 521

  Fly   616 -QPLWDYLYRTFGGGPAVNIIFECEICKRAAETLSRRQQYELNEFTKYNGLQNEFDSTAIYAIAM 679
             :|...:|   .|.|..|          |.|:|    |.......:..:..|:...||:......
Zfish   522 KRPKLTFL---IGQGKPV----------RPAQT----QSSPNCSLSSASHSQSTSSSTSTSTSGF 569

  Fly   680 P-------------WLRSWQQFSRGKTHKDPGPITN---EGIAAP-------------------- 708
            |             :|..:.|.|..::.::.|.:.|   :...||
Zfish   570 PQVKQVNGTHTGASFLVPYGQESSEESDQEAGVLENGSTKTYLAPKITNGNGVKDDAQSHDSSSL 634

  Fly   709 ---------------TENGSATVSCVR-LGSDYAQLN--ARLWRFLHNIYGGGPEIIL----RQA 751
                           .||||.:..|.. .|.|:...|  ::...|.||     .::::    ...
Zfish   635 PHHTSKTNGSNGFHVCENGSDSHVCENGSGPDHTSQNGLSKANGFNHN-----DKVMIDPHTSSQ 694

  Fly   752 LSDEDDAEEIEI---------------IDQDDECDDDEDQDLEGEGEDEEIAAASYQHN------ 795
            :||.....|:|:               ...|..|....::.|....|....:.|..|.:
Zfish   695 ISDLSCCSEMELNLKPAHNESRSSNPASSDDHPCSSPSNKRLNLPSESSSQSVAQIQSSPKESLV 759

  Fly   796 --------HSDT-----------------ESNLGIRNTPSPSPS---TSPSPSLTGTRQPMETES 832
                    |::|                 .|:|.:.|..|...|   |||. .|....:..|.||
Zfish   760 LKTTDTDLHTETASKVELTQRHATHTATGTSDLQVNNNVSLHVSHGHTSPH-KLKEVYRCSEGES 823

  Fly   833 -DLRPSSSKSKRSRSKMKVSALRLNMRNRGK---------RNRSAFKQYAEMFGAKGNYNAHSNA 887
             :.:||.|....|....:..    ..||||.         ::|..::.|.:......:...||..
Zfish   824 KEAKPSHSDKFGSGDGWRSG----EDRNRGSDRPHFSSTPKDRERYRHYRDHSDRSRSRYGHSYQ 884

  Fly   888 EPVVS--------------------------------EKDEKDKDNDRTVAFPSEYSLPISIPFQ 920
            :...|                                .:||:|.:.||.              |.
Zfish   885 DSRRSTSRERYYRDRDLERHWDRFSHHRREHHYFQRRHRDERDWNRDRR--------------FG 935

  Fly   921 SDNFQVNGVHEKSRDKGKLRNSSKSGSTAATKENVTLQKFVTLREANGPSDET 973
            ||:::.:|.|    ::....|.|..|                :.||:|.:..|
Zfish   936 SDSYRPSGYH----NRNGYSNHSHRG----------------MEEAHGRATHT 968

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp20-33	NP_610943.2	UCH	80..538	CDD:425685	103/457 (23%)
		DUSP	560..643	CDD:197831	20/124 (16%)
		DUSP	667..755	CDD:197831	22/145 (15%)
usp42	XP_005169520.1	Peptidase_C19E	113..412	CDD:239126	104/458 (23%)
		U2AF_lg	844..>940	CDD:273727	17/109 (16%)
		SF-CC1	896..>1005	CDD:273721	17/107 (16%)