Protein Alignment Usp20-33 and Usp31

DIOPT Version :9

• Sequence 1: NP_610943.2
• Gene: Usp20-33 / 36580
• FlyBaseID: FBgn0033916
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: XP_038934149.1
• Gene: Usp31 / 308959
• RGDID: 1308183
• Length: 1349
• Species: Rattus norvegicus
• Alignment Length: 1259
• Identity: 256/1259 - (20%)
• Similarity: 419/1259 - (33%)
• Gaps: 454/1259 - (36%)

  Fly    34 AMGDPRSSRCHDKLFSGSLKSLAR----REDSNASDSEGTDTAKGSG------------------ 76
            |...|.|:|......|..||:|:.    ..:..|.|..|..:....|
  Rat    48 APSSPSSARSVGSFMSRVLKTLSTLSHLSSEGAAPDRGGLRSCFPPGPASAPTPPPCPPPPASPA 112

  Fly    77 ---------TGLVGLQNIANTCYMNSALQALSNLPPMTHYFINCSDLVEYIA---------EQSA 123
                     .|:.||:|..|||:||:.||.|||    |..|.....|.:|.|         ||.|
  Rat   113 PPACASEPVPGVAGLRNHGNTCFMNATLQCLSN----TELFAEYLALGQYRAGRPEPEPEPEQPA 173

  Fly   124 RRCK--PGGLAKSYRRLMQEIW------QDVDDPKEFIAPRGILYGIRTVHPMFRGYQQHDTQEF 180
            .|..  .|.:.:....|::.:|      |...|.|..::...:.|         ||..|||.|||
  Rat   174 GRGPHGQGEVTEQLAHLVRALWTLEYTPQHSRDFKSIVSKNALQY---------RGNSQHDAQEF 229

  Fly   181 LRCFMDQLHEELTEQV--------------SMLPQTQN------------QPQYQSL----QQQQ 215
            |...:|::||:|...|              .|:|:..:            |.||:|.    ..|:
  Rat   230 LLWLLDRVHEDLNHAVKQSGQPPLKPPSETDMMPEGPSFPVCSTFVQELFQAQYRSSLTCPHCQK 294

  Fly   216 PSETDDENDDEAAPASLSHA--------------------------------------------- 235
            .|.|.|.....:.|..|.|.
  Rat   295 QSNTFDPFLCISLPIPLPHTRPLYVTVVYQGKCSHCMRIGVAVPLSGTVARLREAVSMETKIPTD 359

  Fly   236 ----SESEYDTCESSMSERSAEVLLKTEY-------FVTP--CRTNG--SNSGLPEGHSVQLQQA 285
                :|..||....|.|:...   |:|.:       |.||  .|..|  |..|:...:::...:.
  Rat   360 QIVLTEMYYDGFHRSFSDTDD---LETVHESDCIFAFETPEIFRPEGILSQRGIHLNNNLNHLKF 421

  Fly   286 PLQHQQKNAS---SAEQKPIEAARSIISDVFDGKLLSSVQCLTCDRVSTREETFQDLSLP----- 342
            .|.|.:.::|   :|:|..::....:.||        .:..|.|:|..|.::. :...||
  Rat   422 GLDHHRLSSSTPTAAKQGRVDLPSRVASD--------KIVLLVCNRACTGQQG-KRFGLPFVLHL 477

  Fly   343 -------IPNRDFLN-------------------------------------VLHQTHSLSVQSL 363
                   :..::.|.                                     :.|.|...:::|.
  Rat   478 EKTVAWDLLQKEILEKMKYFLRPTVSVQVCPFSLRVVSVVGITYLLPQEEQPLCHPTVERALKSC 542

  Fly   364 NAAETS-----------------ARTNEGWL--SWMWNMLRSWIYGP-SVTLYDCMASFFSADEL 408
            ....|:                 ..|.:.::  :....:.:...:.| :.||..|...:...:.|
  Rat   543 GPGGTAHVKLVVEWDKETKDFLFVNTEDEYIPDAESVRLQKEQHHQPQTCTLSQCFQLYTKEERL 607

  Fly   409 KGDNMYSCERCNKLRTGIKYSRVLTLPEVLCIHLKRFRNDLSYSSKISSDVYFPLEGFDMRPYIH 473
            ..|:.:.|..|.:|:.|.....:.|||:||.|||||||.:.....|:.:.|.|||.|.||.|::.
  Rat   608 APDDAWRCPHCKQLQQGSITLSLWTLPDVLIIHLKRFRQEGDRRMKLQNMVKFPLTGLDMTPHVV 672

  Fly   474 KDCKS---------------------EVAIYNLSSVICHHGTVGGGHYTCFARNTLNGKWYEFDD 517
            |..:|                     |..||:|.:|..||||:.|||||.:.:|:::|.||.|||
  Rat   673 KRSQSSWSLPSHWSPWRRPYGLGRDPEDYIYDLYAVCNHHGTMQGGHYTAYCKNSVDGLWYCFDD 737

  Fly   518 QFVTEVSSELVQSCQAYVLFYHKHNPQMKLVRDEAMTLSTSHPLCDSDIQFYITREWLSR----- 577
            ..|.::|.:.|.:..||:|||.:.........:.::..|||..||:         .|:||
  Rat   738 SDVQQLSEDEVCTQTAYILFYQRRTAIPSWSANSSVAGSTSSSLCE---------HWVSRLPGSK 793

  Fly   578 --------------LATFSEPGPINNQEMLCPHGGI-------------LHSKADVISQIAVPIS 615
                          ||:.||...:.. |.....||.             |.|::.|.|.:||.
  Rat   794 QASVTSAASSRRTSLASLSESVEMTG-ERSEDDGGFSTRPFVRSVQRQSLSSRSSVTSPLAVN-- 855

  Fly   616 QPLWDYLYRTFGGGPAVNIIFECEICKRAAETLSRRQQYELNEFTKYNGLQNEFDSTAIYAIAMP 680
                                   |.|.|.:.:||.:.|...|..::::|     ||
  Rat   856 -----------------------ENCMRPSWSLSAKLQMRSNSPSRFSG-----DS--------- 883

  Fly   681 WLRSWQQFSRGKTHKDPGPITNEGIAAPTEN-GSA-----TVSCV----RLGSDYAQLNARLWRF 735
                              ||  .|.|:..|. |.|     ::||.    .|...:.:.:....|.
  Rat   884 ------------------PI--HGSASTLERIGEAGDDKVSISCFGSLRNLSGSHQEPSDSHSRR 928

  Fly   736 LHNIYGGGPEIILRQALSDEDDA-------------------------------EEIEIIDQDDE 769
            .|...|..|..::.....|:.|:                               .:|..:||.|.
  Rat   929 EHKAAGRAPLAVMEGVFKDDSDSGKLNSSVVDTPSKNRAQGDHLPPVSDPFDNNNQIAYVDQSDS 993

  Fly   770 CDDDEDQDLEGEGEDEEIAAASYQHNHSDTESNLGIRNTPSPSPSTSPSPSLTGTRQPMETESDL 834
            .|....::::..             :|||:       .|..|..:|..|||..|..:|.::....
  Rat   994 VDSSPVKEVKSP-------------SHSDS-------LTKKPESTTKRSPSSKGASEPEKSMRKG 1038

  Fly   835 RPS--------SSKSKRSRSKMKVSALRLNMRNRGKRNRSAFKQYAEMFGAKGNYNAHSNAEPVV 891
            ||:        ||.|..|...:|||......|::...:|::           |.:::.::.:|
  Rat  1039 RPALASQESSLSSPSPSSPVPVKVSMKPARCRSKADSSRTS-----------GRHSSSASTQP-- 1090

  Fly   892 SEKDEKDKDNDRTVAFPSEYSLPISIPFQSDNFQVNGVHEKSR---------DKGKLRNSSKSGS 947
              |.|....:..:::.||......:..|   .:..:.:..|:.         ..||.|.|.:|.|
  Rat  1091 --KKESSPRSQESMSSPSPQKQKSASAF---TYSSSSISAKTAPGPATRGPLPSGKSRTSDRSLS 1150

  Fly   948 TAATKENVTLQK-FVTLREANGPS 970
            ...:::::...: .||....:.||
  Rat  1151 RQGSRQSLGSDRASVTSTSTSKPS 1174

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp20-33	NP_610943.2	UCH	79..538	CDD:278850	149/658 (23%)
		Peptidase_C19	80..>204	CDD:271592	45/154 (29%)
		Peptidase_C19R	307..538	CDD:239139	74/320 (23%)
		DUSP	560..643	CDD:197831	20/114 (18%)
		DUSP	667..755	CDD:197831	16/97 (16%)
Usp31	XP_038934149.1	UBP12	<123..762	CDD:227847	152/663 (23%)
		PHA03307	959..>1211	CDD:223039	45/254 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5560
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900