DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Usp20-33 and usp18

DIOPT Version :9

Sequence 1:	NP_610943.2	Gene:	Usp20-33 / 36580	FlyBaseID:	FBgn0033916	Length:	975	Species:	Drosophila melanogaster
Sequence 2:	XP_005164589.1	Gene:	usp18 / 100334535	ZFINID:	ZDB-GENE-100210-2	Length:	337	Species:	Danio rerio

Alignment Length:	381	Identity:	89/381 - (23%)
Similarity:	148/381 - (38%)	Gaps:	84/381 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   170 RGYQQHDT-QEFLRCFMDQLHEELTEQVSMLPQTQNQPQYQSLQQQQPSETDDENDDEAAPASLS 233
            |||:.... .:.|.|.::.|.:..:....:|         ..|.:..||:..::::   .|..|.
Zfish    24 RGYEVRGLFNDGLSCCVNALLQSFSATTELL---------DILNKWNPSDGIEQSN---IPLQLR 76

  Fly   234 HASESEYDTCESSMSERSAEVLLKTEYFVTPCRTNGSNSGLPEGHSVQLQQAPLQHQQKNASSAE 298
            :...|..|...|:..:...:.|    |....||            ..|.....:.|...|.|..:
Zfish    77 NTLLSVRDPSHSAPHKGFLDCL----YRHAICR------------YTQQDADEIFHMILNLSLKQ 125

  Fly   299 QKPIEAARSIISDVFDGKLLSSVQCLTCDRVSTREETFQDLSLPIPNRDFLNVLHQTHSLSVQSL 363
            ....|.|:.|.| ::..::.:.|.|:.|..:.....::  .|||:       |:|:..:
Zfish   126 MPDHELAQEIRS-LYTIEVETQVTCMDCTFIHRLPNSY--FSLPL-------VIHEGEN------ 174

  Fly   364 NAAETSARTNEGWLSWMWNMLRSWIYGPSVTLYDCMASFFSADELKGDNMYSCERCNKLRTGIKY 428
                                          ||..|:.|||...:|:....:.|:||.|.:.....
Zfish   175 ------------------------------TLESCIKSFFKKQKLEVSEKFFCDRCEKKQPCAYE 209

  Fly   429 SRVLTLPEVLCIHLKRFRNDLSYSSKISSDVYFP----LEGFDMRPYIHKDCKSEVAIYNLSSVI 489
            .::::||::||:|||||||:.....|:.|.|.||    :..|......:....|..|.|:|.:||
Zfish   210 QKLVSLPQILCVHLKRFRNEHGLIKKLDSKVTFPETLKISVFAAGQSENAASDSPQADYSLFAVI 274

  Fly   490 CHHGTVGGGHYTCFARNTLNGKWYEFDDQFVTEVSSELVQSC-----QAYVLFYHK 540
            .|.|:...||||.|.|.|.:..||..:|..|.:.:.:.||..     .||:|.|.|
Zfish   275 VHIGSAMFGHYTAFIRQTQDQMWYYANDSRVNQATWKDVQDTYKGRETAYLLLYRK 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Usp20-33	NP_610943.2	UCH	79..538	CDD:278850	87/377 (23%)
		Peptidase_C19	80..>204	CDD:271592	7/34 (21%)
		Peptidase_C19R	307..538	CDD:239139	62/239 (26%)
		DUSP	560..643	CDD:197831
		DUSP	667..755	CDD:197831
usp18	XP_005164589.1	UCH	28..328	CDD:278850	84/373 (23%)
usp18	XP_005164589.1	Peptidase_C19	97..329	CDD:239072	72/293 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D147564at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920