Protein Alignment Usp20-33 and usp20

DIOPT Version :9

• Sequence 1: NP_610943.2
• Gene: Usp20-33 / 36580
• FlyBaseID: FBgn0033916
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: XP_012823238.1
• Gene: usp20 / 100036606
• XenbaseID: XB-GENE-966528
• Length: 932
• Species: Xenopus tropicalis
• Alignment Length: 870
• Identity: 343/870 - (39%)
• Similarity: 474/870 - (54%)
• Gaps: 147/870 - (16%)

  Fly    13 YVEHRNRTIHS-SQGHTLANG--------YAMG-----DPR--------SSRCHDKLFSGS---L 52
            ||:|  .|:|: ::.|.|...        ||..     |||        |.|...:.|..|   |
 Frog   105 YVDH--STLHAQAKKHNLTVNLTTFRVWCYACEKEVFLDPRGPPASQTTSPRLSHRDFPTSAHPL 167

  Fly    53 KS--LARREDSNASDSEGTDTAKGSGTGLVGLQNIANTCYMNSALQALSNLPPMTHYFINCSDLV 115
            ||  :|..:|..:...|  |..|  ..||.|::||.|:||||:|||||||.||:|.:|:.|..||
 Frog   168 KSVPIAVGDDGESESDE--DDIK--PRGLTGMKNIGNSCYMNAALQALSNCPPLTQFFLECGGLV 228

  Fly   116 EYIAEQSARRCKPGGLAKSYRRLMQEIWQDVDDPKEFIAPRGILYGIRTVHPMFRGYQQHDTQEF 180
                    |..|...|.|||::|:.|:|.  .....::.|..:.:||:.::|:||||.|.|||||
 Frog   229 --------RTDKKPALCKSYQKLISELWH--KKRPSYVVPSSLYHGIKLINPLFRGYSQQDTQEF 283

  Fly   181 LRCFMDQLHEELTEQVSMLPQTQNQ---------------------------------------- 205
            |||.||||||||.|.|.:..|.:.:
 Frog   284 LRCLMDQLHEELKEPVPLETQEREEEDRDDQREGERGGTVEEDFLSCDSGGEMGDGEGGGGVGTL 348

  Fly   206 ---------------PQYQSLQQQQPS----ETDDENDDEAAPASLSHASESEYDT---CES-SM 247
                           .:.:.|::::.|    .|..|..||.|....:...|.:.|.   |.| |.
 Frog   349 SEMELLIREEVGRGLSEKEKLKERKLSYCHRRTSSEQADEDADVDTAMIPEPDNDAYVHCSSRSC 413

  Fly   248 SERSAEVLLKTEYFVTPCRTNGSNSGLPEGHSVQLQQAPLQHQQKNASSAEQKPIEAARSIISDV 312
            |....|.:.|  :..||.|    :|.|...||..|::|.:....|..|....      ||:|||:
 Frog   414 SPHPVESISK--HSSTPPR----SSPLRTSHSYVLKKAQVLSGGKKRSEVRY------RSVISDI 466

  Fly   313 FDGKLLSSVQCLTCDRVSTREETFQDLSLPIPNRDFLNVLHQT-HSLSVQSLNAAETSARTNEGW 376
            |||.:||.|||||||||||..|||||||||||.::.|..||.| |..:|........|... :||
 Frog   467 FDGSILSLVQCLTCDRVSTTIETFQDLSLPIPGKEDLAKLHSTIHQSAVSKAGTCGDSYAA-QGW 530

  Fly   377 LSWMWNMLR--------SWIYGPSVTLYDCMASFFSADELKGDNMYSCERCNKLRTGIKYSRVLT 433
            ||:..:.:|        ||.:||.:||.||:|:||:|||||||||||||||.|||.|:||.:||.
 Frog   531 LSFFMDYIRRFVVSCIPSWFWGPMITLEDCLAAFFAADELKGDNMYSCERCKKLRNGVKYCKVLR 595

  Fly   434 LPEVLCIHLKRFRNDLSYSSKISSDVYFPLEGFDMRPYIHKDCKSEVAIYNLSSVICHHGTVGGG 498
            |||:|||||||||:::.||.||.|.|.|||||.::||::.|:|.|.:..|:|.:||||||:...|
 Frog   596 LPEILCIHLKRFRHEVMYSFKIGSHVSFPLEGLNLRPFLAKECVSRITTYDLLAVICHHGSASSG 660

  Fly   499 HYTCFARNTLNGKWYEFDDQFVTEVSSELVQSCQAYVLFYHKHNPQMKLVRDEAMTLSTSHPLCD 563
            ||..:.:|.:||:|||||||:||||...:||:.:||||||.|.:.:.:..|.:.::|:.   :.:
 Frog   661 HYISYCQNVINGQWYEFDDQYVTEVHETVVQNAEAYVLFYRKSSEEAERERQKVVSLAA---MKE 722

  Fly   564 SD-IQFYITREWLSRLATFSEPGPINNQEMLCPHGGILHSKADVISQIAVPISQPLWDYLYRTFG 627
            |. :||||:||||::..||:||||||||..||.||||..:|...|..:.|.:.|.:|:|||..||
 Frog   723 SGLLQFYISREWLNKFNTFAEPGPINNQSFLCSHGGIPPNKYHYIDDLVVILPQSVWEYLYNRFG 787

  Fly   628 GGPAVNIIFECEICKRAAETLSRRQQYELNEFTKYN-GLQNEFDSTAIYAIAMPWLRSWQQFSRG 691
            ||||||.::.|.||:...|.|::|::.|::.|.|.| ..|.|...:.||.|:|.|.|.|:.|.:.
 Frog   788 GGPAVNHLYVCSICQVEIEALAKRRKTEIDTFIKLNKAFQAEEAPSVIYCISMQWFREWEAFVKA 852

  Fly   692 KTHKDPGPITNEGIAAPTENGSATVSCVRLGSDYAQLNARLWRFLHNIYGGGPEIILRQALSDED 756
            |....||||.|..:|....:|...   ::.|:||.|::...|.:|.|:|||||||.:||.::...
 Frog   853 KDSDPPGPIDNSKVALTKSSGQVQ---LKQGADYGQISEETWNYLLNVYGGGPEIAIRQTVAQYQ 914

  Fly   757 DAEEIEIIDQDDECDDDEDQDLEGE 781
            :||.:.           .:|.:|.|
 Frog   915 EAEHLH-----------GEQKIEAE 928

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp20-33	NP_610943.2	UCH	79..538	CDD:278850	223/530 (42%)
		Peptidase_C19	80..>204	CDD:271592	59/123 (48%)
		Peptidase_C19R	307..538	CDD:239139	136/239 (57%)
		DUSP	560..643	CDD:197831	44/83 (53%)
		DUSP	667..755	CDD:197831	33/87 (38%)
usp20	XP_012823238.1	UBP14	51..>311	CDD:227532	85/221 (38%)
		UCH	193..700	CDD:366104	222/529 (42%)
		DUSP	720..803	CDD:197831	44/82 (54%)
		DUSP	828..912	CDD:197831	33/86 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	394	1.000	Domainoid score	I762
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4861
Inparanoid	1	1.050	577	1.000	Inparanoid score	I1024
OMA	1	1.010	-	-		QHG46045
OrthoDB	1	1.010	-	-		D147564at2759
OrthoFinder	1	1.000	-	-		FOG0003021
OrthoInspector	1	1.000	-	-		otm48952
Panther	1	1.100	-	-	LDO	PTHR21646
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6373
SonicParanoid	1	1.000	-	-		X2011
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110