Protein Alignment Snrk and KSP1

DIOPT Version :10

• Sequence 1: NP_610942.2
• Gene: Snrk / 36579
• FlyBaseID: FBgn0033915
• Length: 860
• Species: Drosophila melanogaster
• Sequence 2: NP_011950.1
• Gene: KSP1 / 856482
• SGDID: S000001124
• Length: 1029
• Species: Saccharomyces cerevisiae
• Alignment Length: 1014
• Identity: 194/1014 - (19%)
• Similarity: 346/1014 - (34%)
• Gaps: 334/1014 - (32%)

  Fly     1 MTL--ETQPVGGVSDGKIAGLYDLEETLGSGHFAVVKLARHVFTGAKVAVKVVDK---------- 53
            |||  |....||:.:.:...:.|:.|    |.:..|.||:.|.....||||.:.|
Yeast     1 MTLDYEIYKEGGILNNRYQKIEDISE----GSYGYVSLAKDVREKRLVAVKYIFKLEDDGQYDGP 61

  Fly    54 -----------------TKLDD------------------VSKAHLFQEVR-------------- 69
                             ||:|.                  ..|.:|::..:
Yeast    62 QDDENDCDSSDCDDDEDTKVDTDRHENENGNASSNNGSSREKKHNLYKHKKSLISSKVKSRLSNN 126

  Fly    70 -CM----------KLVQHPNVVRLYEVIDTQTKLYLVLELGDGGDLYDYIMKHDSGLSEELARKY 123
             |:          |:.:|.|:..|.:..|:    |:::|...|||||:.|.........:.....
Yeast   127 ICLEAMYEVDIQTKIGRHQNIAALLDFFDS----YIIMEYCSGGDLYEAIKADAVPKKTKSITHI 187

  Fly   124 FRQILRAITYCHQLHVVHRDLKPENVVFFEKLGLVKLTDFGFSNKFLPGQKLETFCGSLAYSAPE 188
            ..||:.||.|.|...:.|||:||||::.......:||||:|.:.  .....::...||..|.:||
Yeast   188 ITQIMDAIEYVHNKGIYHRDIKPENILISGIDWTIKLTDWGLAT--TDKTSMDRNVGSERYMSPE 250

  Fly   189 ILLGDS----------YDAPAVDIWSLGVILYMLVCGQAPFEKANDSET----LTMIMDCKYTVP 239
            :.  ||          ||...||:|::|::...:|..:.||..||.|:.    .....:..:.|.
Yeast   251 LF--DSNLDIKERKEPYDCAKVDLWAMGIVFLNIVFHKNPFSIANQSDKSFCYFAANREALFDVF 313

  Fly   240 SHVSTDCRDLIASMLVRDPKKRATVEEIASSAWLKPIDEPDSTTSTSEHFLPLVSREQLGEEDHA 304
            |.::.|...::...|..||..|..
Yeast   314 STMAYDFFQVLRYSLTIDPANRDL----------------------------------------- 337

  Fly   305 FIIQKMINGNIASKEEILQALDKNKYNHITATYFLLAELRLRRRREELAQKQRLLNDASMKVGDA 369
                ||:...:.:..|  ..||...||::...|                       :.:|..|
Yeast   338 ----KMMRTELQNLSE--YTLDDEYYNNLDEGY-----------------------EETMIDG-- 371

  Fly   370 SRKLVPEKPSPTEAQKGGVPISINVTPAAQFANDGGKPD-KRSRKCSIVREEDEEESATECTAVG 433
                :|.:|.|..:    .|:|: .||.:. :|....|: |:....:.|.|....:.:.......
Yeast   372 ----LPPQPVPPSS----APVSL-PTPISS-SNKQHMPEFKKDFNFNNVNERKRSDVSQNQNVAS 426

  Fly   434 NELKVTSSSRREAFSDS-PFSRSIHERSSSEPGNQTKGEQIANSGVPSHSRTKIVVSVDATLAHK 497
            ...|..|:.:::.|:.. ..:.|.|||:.|.|                              ..|
Yeast   427 GFFKKPSTQQQKFFNQGYNTTLSTHERAKSAP------------------------------KFK 461

  Fly   498 LKQMEKSAKIDEDTLSGLKELEIGKLKPLPSSSKNPVLTHRRTKLNKIRTPSCSSSE-----ASD 557
            .|:..|..:.|.         :..|...:....|:.:|...|..|. |.||:...:.     .:.
Yeast   462 FKKRNKYGRTDN---------QFSKPVNIEDRKKSKILKKSRKPLG-IPTPNTHMNNFFHDYKAR 516

  Fly   558 DDTKTRN--------KKKINKFVGDTPVRFRMHRRDSHDDSSDSQDQLYPPPGSASNAGNFISKS 614
            |:..||:        .:.:..|..:...::|.:|..::::::.:.:.       .||..||.:.:
Yeast   517 DEFNTRDFFTPPSVQHRYMEGFSNNNNKQYRQNRNYNNNNNNSNNNH-------GSNYNNFNNGN 574

  Fly   615 GSVSGKKEGQSQYKEPNNKSDENRKSHSQKNRKQHNKDHVDKHSHAERQLADSSTATTGNS---- 675
            ..:.|..:..::|:.|::.|...:...|:.|...::.::...:.:|.|    .||.|..:|
Yeast   575 SYIKGWNKNFNKYRRPSSSSYTGKSPLSRYNMSYNHNNNSSINGYARR----GSTTTVQHSPGAY 635

  Fly   676 ------------TNRRRRIRESQSLDRIT------EAQEYEMRHRCYAESEAASSSSSSTQHIDQ 722
                        ||:..|:.:|.:.|..|      ..||:      |.:....|.....:..:
Yeast   636 IPPNARNHHVSPTNQFLRVPQSTAPDISTVLGGKPSYQEH------YTQDSMDSEGDHDSDDV-- 692

  Fly   723 RYSLLSLNTSTFSVAETKEEYDEEADATNATDQIMNTLNAAKATLQQEQYFNNNTNLSRNFNHNH 787
                      .|::.|...::....|..:..|.:.:|...:    ..|.:.:.:||.:.|.|:||
Yeast   693 ----------LFTLEEGDHDFVNGMDNLSINDHLPHTTVGS----HNEVFVHASTNHNNNGNNNH 743

  Fly   788 -------NQ-----------SIIHISSQKANGKKSNETPKDI----------YNLNSIEHIDLIL 824
                   ||           :.:||::   |..:|||.| |:          .||:| ..||.||
Yeast   744 IDTNSTTNQYHRQYIPPPLTTSLHINN---NNNESNELP-DLLKSPASSEAHLNLSS-GPIDPIL 803

  Fly   825 EDKSLTKAIHVTGSKCFVTMKKIRRL--------GKYFP 855
            ......:..|.:.||   .:::.|||        |.|.|
Yeast   804 TGNIGNRYSHSSDSK---ELEQERRLSMEQKFKNGVYVP 839

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snrk	NP_610942.2	STKc_SNRK	16..273	CDD:270976	75/340 (22%)
		UBA_SNRK	296..338	CDD:270524	7/41 (17%)
KSP1	NP_011950.1	STKc_Pat1_like	17..348	CDD:270895	77/387 (20%)