Protein Alignment CG8485 and KIN4

DIOPT Version :9

• Sequence 1: NP_610942.2
• Gene: CG8485 / 36579
• FlyBaseID: FBgn0033915
• Length: 860
• Species: Drosophila melanogaster
• Sequence 2: NP_014876.1
• Gene: KIN4 / 854408
• SGDID: S000005759
• Length: 800
• Species: Saccharomyces cerevisiae
• Alignment Length: 856
• Identity: 200/856 - (23%)
• Similarity: 339/856 - (39%)
• Gaps: 231/856 - (26%)

  Fly    18 GLYDLEETLGSGHFAVVKLARHVFTGA--------KVAVKVV--DKTKLDDVSKAHLFQEVRCMK 72
            |.|.:..|||.|.|..|||.   :|.|        :||:|::  |..|.|...:..:::|:..:|
Yeast    44 GPYIIGSTLGEGEFGKVKLG---WTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALK 105

  Fly    73 LVQHPNVVRLYEVIDTQTKLYLVLELGDGGDLYDYIMKHDSGLSEELARKYFRQILRAITYCHQL 137
            .:.|||::.|.||:.....:.:|||...||:.|.||.: ...|.|..|.:.|.|::..:.|.|..
Yeast   106 HLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQR-KRRLKESSACRLFAQLISGVNYMHYK 169

  Fly   138 HVVHRDLKPENVVFFEKLGLVKLTDFGFSNKFLPGQKL-ETFCGSLAYSAPEILLG-DSYDAPAV 200
            .:||||||.||::..:...|| :|||||.|:|....:| :|.|||..|:|||:::. .:|:|...
Yeast   170 GLVHRDLKLENLLLDKHENLV-ITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKA 233

  Fly   201 DIWSLGVILYMLVCGQAPFEKANDSET-------LTMIMDCKYTVPSHVSTDCRDLIASMLVRDP 258
            |:||.|||||.::.|..|::..:::.|       ...|.......|.:::...|||:..:||.:|
Yeast   234 DVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQTPLKFPEYITPIPRDLLRRILVPNP 298

  Fly   259 KKRATVEEIASSAWLKPIDEPDSTTSTSEHFL---PLVSREQLGEEDHAFIIQKMIN-GNI---- 315
            ::|..::.|....||||          .|.||   |....|.|.:|.     .|..| |::
Yeast   299 RRRINLQTIKRHVWLKP----------HEAFLSIQPNYWDEHLQKER-----PKPPNKGDVGRHS 348

  Fly   316 ---ASKEEILQALDKNKYNHITATYFLLAELRLRRRREELAQKQRLLNDASMKVGDASRKLVPEK 377
               :|.....::.|:|.         |:.|..|.:.|                   .|.:|...:
Yeast   349 TYSSSASSYSKSRDRNS---------LIIESTLEQHR-------------------MSPQLATSR 385

  Fly   378 P-SPTEAQKGGVPISINVTP-AAQFANDGGKPDKRSRKCSIVRE-------EDEEESA------T 427
            | |||.:.  |..:.:|.|. ..:.:|..|  ::.|..|...|:       :.|:.||      .
Yeast   386 PASPTFST--GSKVVLNDTKNDMKESNING--ERTSASCRYTRDSKGNGQTQIEQVSARHSSRGN 446

  Fly   428 ECTAVGNELKVTSSSRREAFSDSPFSR-SIHERSSSEPG-NQTKGEQIANSGVP-SHSR-TKIVV 488
            :.|:|...:.:..|.......::|.|: :.|.:.||:.. .|.:..:|.|..|| |..| |....
Yeast   447 KHTSVAGLVTIPGSPTTARTRNAPSSKLTEHVKDSSQTSFTQEEFHRIGNYHVPRSRPRPTSYYP 511

  Fly   489 SVDATLAHKLKQMEKSAKIDEDTLSGLKELEIGKLKPLPSSSKNPVLTHRRTKLNKIRTPSCSSS 553
            .:....|             :::|:.:...::|....| :.:|:||..:.....||....:.|..
Yeast   512 GLSRNTA-------------DNSLADIPVNKLGSNGRL-TDAKDPVPLNAIHDTNKATISNNSIM 562

  Fly   554 EASDDDTKTRNKKKINKFVGD--------TPVRFRMHRRDSHDDSSDSQDQLYPPPGSASNAGNF 610
            ..|:......:....:..:||        |.|..::::..:|..:.:...:....|.|.|..  .
Yeast   563 LLSEGPAAKTSPVDYHYAIGDLNHGDKPITEVIDKINKDLTHKAAENGFPRESIDPESTSTI--L 625

  Fly   611 ISKSGSVSGKKEGQSQYKEPNNKSDENRKSHSQKNRKQHNKDHVDKHSHAERQLADSSTATTGNS 675
            ::               |||.|.:||               |||           :|.....|:|
Yeast   626 VT---------------KEPTNSTDE---------------DHV-----------ESQLENVGHS 649

  Fly   676 TNRRRRIRESQSLDRITEAQEYEMRHRCYAESEAASSSSSSTQHIDQRYSLLSLNTSTFSVAETK 740
            :|:                            |:|:|...|...:..:|:|.:||.:|
Yeast   650 SNK----------------------------SDASSDKDSKKIYEKKRFSFMSLYSS-------- 678

  Fly   741 EEYDEEADATNATDQIMNTLNAAKATLQQEQYFNNNTNL-SRNFNHNHNQSIIHISSQKANG--- 801
                               ||.:::|::......|...: |||.:...|:|.|.|:.|:...
Yeast   679 -------------------LNGSRSTVESRTSKGNAPPVSSRNPSGQSNRSNIKITQQQPRNLSD 724

  Fly   802 ------KKSNE 806
                  ||.|:
Yeast   725 RVPNPDKKIND 735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8485	NP_610942.2	STKc_SNRK	16..273	CDD:270976	90/273 (33%)
		S_TKc	20..273	CDD:214567	89/271 (33%)
		UBA_SNRK	296..338	CDD:270524	9/49 (18%)
KIN4	NP_014876.1	STKc_Kin4	44..313	CDD:270978	90/273 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345321
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I953
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.980