Protein Alignment Snrk and TSSK1B

DIOPT Version :10

• Sequence 1: NP_610942.2
• Gene: Snrk / 36579
• FlyBaseID: FBgn0033915
• Length: 860
• Species: Drosophila melanogaster
• Sequence 2: NP_114417.1
• Gene: TSSK1B / 83942
• HGNCID: 14968
• Length: 367
• Species: Homo sapiens
• Alignment Length: 386
• Identity: 121/386 - (31%)
• Similarity: 190/386 - (49%)
• Gaps: 60/386 - (15%)

  Fly    20 YDLEETLGSGHFAVVKLARHVFTGAKVAVKVVDKTKLD-DVSKAHLFQEVRCMKLVQHPNVVRLY 83
            |.|...||.|.:|.||.|........||:|::|:.|.. |..:..|.:|:..:.::.|.::::.|
Human    12 YLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTY 76

  Fly    84 EVIDT-QTKLYLVLELGDGGDLYDYIMKHDSGLSEELARKYFRQILRAITYCHQLHVVHRDLKPE 147
            |:.:| ..|:|:|:||...|||.: ::|....|.|:.|||.|.|:..||.|||.|.|||||||.:
Human    77 EIFETSHGKVYIVMELAVQGDLLE-LIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCD 140

  Fly   148 NVVFFEKLGLVKLTDFGFSNKFLPGQK-----LETFCGSLAYSAPEILLGDSYDAPAVDIWSLGV 207
            |:: .:|...:||:||.||.:.|....     .:|||||.||:|||:|.|..|.....|||||||
Human   141 NLL-LDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGV 204

  Fly   208 ILYMLVCGQAPFEKANDSETLTMIMDCKYTVP--SHVSTDCRDLIASMLVRDPKKRATVEEIASS 270
            |||::|||..|::.:|..:.|.:..:.:...|  .|::.:|:|||..||..|..:|..::||.|.
Human   205 ILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSH 269

  Fly   271 AWLKP---------IDEPDSTTSTSEHFLPLVSREQLGEEDHAFIIQKMINGNIASKEEILQALD 326
            .|::|         |::...::..:|   ||.:.|...::..|
Human   270 CWMQPKARGSPSVAINKEGESSRGTE---PLWTPEPGSDKKSA---------------------- 309

  Fly   327 KNKYNHITATYFLLAELRLRRRREELAQKQRLLNDASMKVGDASRKL-VPEKPSPTEAQKG 386
                          .:|......:..||.:......:|::...|..| .|.|||..|.::|
Human   310 --------------TKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTMETEEG 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snrk	NP_610942.2	STKc_SNRK	16..273	CDD:270976	101/261 (39%)
		UBA_SNRK	296..338	CDD:270524	2/41 (5%)
TSSK1B	NP_114417.1	STKc_TSSK1_2-like	10..272	CDD:271067	101/261 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	276..367		18/120 (15%)