Protein Alignment Snrk and nuak1a

DIOPT Version :10

• Sequence 1: NP_610942.2
• Gene: Snrk / 36579
• FlyBaseID: FBgn0033915
• Length: 860
• Species: Drosophila melanogaster
• Sequence 2: XP_690066.1
• Gene: nuak1a / 561563
• ZFINID: ZDB-GENE-041210-122
• Length: 617
• Species: Danio rerio
• Alignment Length: 646
• Identity: 188/646 - (29%)
• Similarity: 280/646 - (43%)
• Gaps: 160/646 - (24%)

  Fly    20 YDLEETLGSGHFAVVKLARHVFTGAKVAVKVVDKTKL-DDVSKAHLFQEVRCMKLVQHPNVVRLY 83
            |:|.||||.|.:..||.|....||..||:|.:.|.|: |:....|:.:|:..|..::||:::.:|
Zfish    53 YELLETLGRGTYGKVKKAIERHTGRVVAIKSIRKEKIKDEQDMVHIRREIEIMSSLRHPHIISIY 117

  Fly    84 EVIDTQTKLYLVLELGDGGDLYDYIMKHDSGLSEELARKYFRQILRAITYCHQLHVVHRDLKPEN 148
            ||.:.:.|:.:|:|....|:|||||.:. ..|:|...|.:||||:.|:.|||:..|||||||.||
Zfish   118 EVFENKDKIVIVMEYASKGELYDYISER-RRLTERETRHFFRQIVSAVHYCHKKGVVHRDLKLEN 181

  Fly   149 VVFFEKLGLVKLTDFGFSNKFLPGQKLETFCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLV 213
            ::..:. |.:|:.|||.||.:...:.|:|||||..|::|||:.|..|..|.||.|:|||:||.||
Zfish   182 ILLDDN-GNIKIADFGLSNLYHKDKLLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLV 245

  Fly   214 CGQAPFEKANDSETLTMIMDCKYTVPSHVSTDCRDLIASMLVRDPKKRATVEEIASSAWLK---P 275
            .|..||:..:....:..|.:.:|..|.. |:|.|.||..||:.:|.:|||||:||:..|:.   .
Zfish   246 YGTMPFDGGDHQRLIRQISNGEYREPPQ-SSDARGLIRWMLMVNPDRRATVEDIANHWWVNWGWK 309

  Fly   276 IDEPDSTTSTSEHFLPLVSREQLGEEDHAFI------------IQKMINGNIASKEEILQALDKN 328
            ....|..|. .|:..|:::|         ||            :|:...||:
Zfish   310 SSVCDCQTQ-RENSSPMLAR---------FIDWQNRTDVRPGKVQRPEPGNV------------- 351

  Fly   329 KYNHITATYFLLAELRLRRRREELAQKQRLLNDASMKVGDASRKLVPEKPSPTEAQKGGVPISIN 393
              |:.|.|    ...|||:..:|        |||.|      ..:..|||....      |.||.
Zfish   352 --NNTTLT----PARRLRKSMKE--------NDAGM------WGVAEEKPGLKR------PKSIL 390

  Fly   394 VTPAAQFANDGGKPDKRSRK-CSI-----VREEDEEESAT---ECTAVGNELKVTS--------- 440
            .|.|.       ..|:||:. |.:     :..:|.|..::   |.|..|:..|:.|
Zfish   391 KTRAT-------SGDQRSQSLCEVELRRTICYQDVESGSSPEREDTLGGSPAKMVSMLPKKGILK 448

  Fly   441 --SSRREAFSDSPFSRSIHERSSS---------EPGNQT--------KGEQIANSGVPSHSRTKI 486
              ..|...:..||      |||.|         :|.|.:        ||....|....:||...:
Zfish   449 NNQQRESGYYSSP------ERSESSELLGGATVQPPNSSPTKRSVGRKGILKRNGKYSTHSAVGV 507

  Fly   487 --VVSVDATLAHKLKQMEKSAKIDEDTLSGLKELEIGKLKPLPSSSKNPVLTHRRTKLNKIRTPS 549
              .:..||||..  .|...|:.:.|:|  ||.  .||...| |:|.|                |:
Zfish   508 HGDIQADATLTR--SQSRPSSIVYEET--GLS--CIGLDWP-PTSPK----------------PN 549

  Fly   550 CSSSEASDDDTKTRNKKKINKFVGDTPVRFRMHRRDSHDDSSDSQDQLYPPPGSASNAGNF 610
            ...|.:::|..:....:.:...   .|:......|.              ||||..:.|:|
Zfish   550 IRGSLSAEDLLQMAGFRGLQTV---APLHGGRGNRS--------------PPGSPGDNGSF 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snrk	NP_610942.2	STKc_SNRK	16..273	CDD:270976	106/253 (42%)
		UBA_SNRK	296..338	CDD:270524	8/53 (15%)
nuak1a	XP_690066.1	STKc_NUAK	52..304	CDD:270975	106/253 (42%)