Protein Alignment Snrk and nuak2

DIOPT Version :10

• Sequence 1: NP_610942.2
• Gene: Snrk / 36579
• FlyBaseID: FBgn0033915
• Length: 860
• Species: Drosophila melanogaster
• Sequence 2: XP_688764.3
• Gene: nuak2 / 560275
• ZFINID: ZDB-GENE-050208-563
• Length: 576
• Species: Danio rerio
• Alignment Length: 564
• Identity: 168/564 - (29%)
• Similarity: 250/564 - (44%)
• Gaps: 122/564 - (21%)

  Fly    20 YDLEETLGSGHFAVVKLARHVFTGAKVAVKVVDKTKL-DDVSKAHLFQEVRCMKLVQHPNVVRLY 83
            |:..||||.|.:..||.|.. .:|..||:|.:.|.|: |:....|:.:|:..|..:.||:::.:|
Zfish    29 YEFLETLGKGTYGRVKKAMD-RSGTAVAIKSIRKEKIRDEQELTHIRREIEIMSSLSHPHIISIY 92

  Fly    84 EVIDTQTKLYLVLELGDGGDLYDYIMKHDS-GLSEELARKYFRQILRAITYCHQLHVVHRDLKPE 147
            ||.:.:.|:.:|:||...|||:|||.  || .|:|..||.:||||:.|:.|||:..:||||||.|
Zfish    93 EVFENKDKIVIVMELASRGDLFDYIC--DSQPLAETQARHFFRQIVSAVHYCHRNGIVHRDLKLE 155

  Fly   148 NVVFFEKLGLVKLTDFGFSNKFLPGQKLETFCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYML 212
            |:: .:..|.:|:.|||.||.:...:.|:|:|||..|::|||:.|..|..|.||.|||||:||.|
Zfish   156 NIL-LDCNGNIKIADFGLSNLYRGDKLLQTYCGSPLYASPEIVNGRPYRGPEVDSWSLGVLLYTL 219

  Fly   213 VCGQAPFEKANDSETLTMIMDCKYTVPSHVSTDCRDLIASMLVRDPKKRATVEEIASSAWLKPID 277
            :.|..||:..:....:..|....|..||..|..| .||..||:.:|::|||:|:||...|:....
Zfish   220 MHGAMPFDGHDHRILVQQISSGSYRKPSKPSDAC-GLIRWMLMVNPERRATLEDIAGHWWVNWGF 283

  Fly   278 EPDSTTSTSEHFLPLVSRE-----QLGEEDHAFIIQKMINGNIA-----SKEEILQALDKNKYNH 332
            |           |||:::.     ....|..|.:.|...:..||     |...:|::..|
Zfish   284 E-----------LPLLAQSDPATAHPASEPAAVVSQTNGSTRIADWLRRSSRPLLESSSK----- 332

  Fly   333 ITATYFLLAELRLRRRREELAQKQRLLNDASMKVGDASRKLVPEKPSPTEA--QKGG-----VPI 390
                      :|...|..|..|:||.:. .|.|..:.|:.: .|.|.|.:.  :|.|     .|.
Zfish   333 ----------MRCLLRTGEPVQRQRSIR-RSRKENNISQSM-QETPRPAKGILKKRGSLKLKAPP 385

  Fly   391 SINVTPAAQFANDGGKPDKRSRKCSIVREEDEEESATECTAV------GNELKVTSSSRREAFSD 449
            ...:||.                        ||:|:....|.      ...||..|.|.....|.
Zfish   386 EPQLTPL------------------------EEKSSNALVAAVLPPPPKGILKKPSESESSCCSL 426

  Fly   450 SPFSRSIHERSSSEPGNQTKGEQIAN-SGVPSHSRTKIVVSVDATLAHKLKQMEKSAKIDEDTLS 513
            ||               |..|:.:.| |.||                |:...:::.:|..    .
Zfish   427 SP---------------QNSGQTLGNPSPVP----------------HRKGILKRHSKFS----G 456

  Fly   514 GLKELEIGKLKPLPSSSKNPVLTHRRTKLNKIRTPSCSSSEASD 557
            ||:  |.|.|..|...|  |.:.:|......:...|..|||:.|
Zfish   457 GLQ--EFGSLDQLALCS--PAVVNRPRPSGAVSEDSILSSESFD 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snrk	NP_610942.2	STKc_SNRK	16..273	CDD:270976	105/254 (41%)
		UBA_SNRK	296..338	CDD:270524	8/51 (16%)
nuak2	XP_688764.3	STKc_NUAK2	25..279	CDD:271063	105/254 (41%)