Protein Alignment CG8485 and AMPKalpha

DIOPT Version :9

• Sequence 1: NP_610942.2
• Gene: CG8485 / 36579
• FlyBaseID: FBgn0033915
• Length: 860
• Species: Drosophila melanogaster
• Sequence 2: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Alignment Length: 566
• Identity: 169/566 - (29%)
• Similarity: 263/566 - (46%)
• Gaps: 93/566 - (16%)

  Fly    18 GLYDLEETLGSGHFAVVKLARHVFTGAKVAVKVVDKTK---LDDVSKAHLFQEVRCMKLVQHPNV 79
            |.|.|..|||:|.|..||:..|..|..|||||::::.|   ||.|.|  :.:|::.:||.:||::
  Fly    26 GHYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGK--IRREIQNLKLFRHPHI 88

  Fly    80 VRLYEVIDTQTKLYLVLELGDGGDLYDYIMKHDSGLSEELARKYFRQILRAITYCHQLHVVHRDL 144
            ::||:||.|.:.:::::|...||:|:|||:||.. |.|..||::|:||:..:.|||:..:|||||
  Fly    89 IKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGK-LQEHQARRFFQQIISGVDYCHRHMIVHRDL 152

  Fly   145 KPENVVFFEKLGLVKLTDFGFSNKFLPGQKLETFCGSLAYSAPEILLGDSYDAPAVDIWSLGVIL 209
            ||||::....:. ||:.|||.||..|.|:.|.|.|||..|:|||::.|..|..|.|||||.||||
  Fly   153 KPENLLLDHNMH-VKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVIL 216

  Fly   210 YMLVCGQAPFEKANDSETLTMIMDCK---YTVPSHVSTDCRDLIASMLVRDPKKRATVEEIASSA 271
            |.|:||..||:   |....|:....|   :.:|.:::....:|:..||..||.|||.:|||....
  Fly   217 YALLCGTLPFD---DEHVPTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHE 278

  Fly   272 WLKPIDEPDSTTSTSEHFLPLVSREQLGEEDHAFIIQKMINGNIASKEEILQALDKNKYNHITAT 336
            |.:. |.|       .:..|....:.....|...:.:......:...|.....|..:.::.:...
  Fly   279 WFQK-DLP-------AYLFPSSIEQDSNVIDTYAVAEVCTKFGVKETEVHNSLLSGDPHDQLAIA 335

  Fly   337 YFLLAELRLRRRREELAQKQRLLNDASMKVGDASRKLV----PEKPSPTEAQK------------ 385
            |.|:.:            .:|..:||:.::.:.:...|    |..|.|...|.
  Fly   336 YHLIID------------NKRFADDAANQINEINNFFVAGSPPPPPPPPVPQSSMDHQAPLATVT 388

  Fly   386 --GGVPISI-NVTPAAQFANDGGKPDK----RSRKCSIVREEDEEESATECTAVGNELKVTSSSR 443
              ||...|. ..||....|  ||.|..    |.....|....|.:.:.:..|:.|.     :...
  Fly   389 VGGGTSASSGTATPVPPVA--GGTPSSTIPIRPHPERIAPMRDRQLAMSVQTSGGG-----AFPE 446

  Fly   444 REAFSDSPFSRS---IHERSSSEPGNQTKGE------------QIANSGVPSHSRTK---IVVSV 490
            :.|...:|..|:   :..||.|:| |....|            :|.|   |.|.|.:   :....
  Fly   447 KTARGGTPIKRAKWHLGIRSQSKP-NDIMLEVYRAMKALSYEWKIIN---PYHVRVRRQNVKTGK 507

  Fly   491 DATLAHKLKQME-KSAKIDEDTLSGLKELEIG------KLKPLPSS 529
            .:.::.:|.|:: ||..:|..:|:. .|:|.|      .|.|.|.|
  Fly   508 FSKMSLQLYQVDAKSYLLDFKSLTN-DEVEQGDDVIMESLTPPPLS 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8485	NP_610942.2	STKc_SNRK	16..273	CDD:270976	111/260 (43%)
		S_TKc	20..273	CDD:214567	110/258 (43%)
		UBA_SNRK	296..338	CDD:270524	3/41 (7%)
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	111/260 (43%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	8/74 (11%)
		AMPKA_C	457..580	CDD:213378	25/101 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461626
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24343
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940