Protein Alignment Snrk and Gm14147

DIOPT Version :10

• Sequence 1: NP_610942.2
• Gene: Snrk / 36579
• FlyBaseID: FBgn0033915
• Length: 860
• Species: Drosophila melanogaster
• Sequence 2: XP_355352.1
• Gene: Gm14147 / 381390
• MGIID: 3651555
• Length: 640
• Species: Mus musculus
• Alignment Length: 622
• Identity: 167/622 - (26%)
• Similarity: 277/622 - (44%)
• Gaps: 131/622 - (21%)

  Fly    20 YDLEETLGSGHFAVVKLARHVFTGAKVAVKVVDKTKLDDVSKAHLFQ-EVRCMKLVQHPNVVRLY 83
            |::..|||.|.|..||||.|:.|..|||:|::.:.:     |..|.| |:..||.:.||::::|.
Mouse    24 YEILTTLGQGTFGDVKLANHLVTQTKVAIKILPQNR-----KNPLVQPEIEIMKSLDHPHIIKLL 83

  Fly    84 EVIDTQTKLYLVLELGDGGDLYDYIMKHDSG-LSEELARKYFRQILRAITYCHQLHVVHRDLKPE 147
            .:|||...:::|||...||:|.:.|  .:.| |:|....:.|:|::.|:.|||:..:||||||||
Mouse    84 HIIDTTRNIFIVLEHAVGGELMNRI--EEFGYLAEVECHRLFKQLVYALQYCHEKGIVHRDLKPE 146

  Fly   148 NVVFFEKLGLVKLTDFGFSNKFLPGQKLETFCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYML 212
            |:: .:..|.|||||||...|.:.||||.||||:|.|.|||:.....||..|.|:|||||:||.:
Mouse   147 NIL-LDHRGNVKLTDFGLGTKIIMGQKLVTFCGTLPYCAPELFEDRGYDGRATDVWSLGVVLYFM 210

  Fly   213 VCGQAPFEKANDSETLTMIMDCKYTVPSHVSTDCRDLIASMLVRDPKKRATVEEIASSAWLKPID 277
            ..|..||...:.......|:..||.....:|.:..::||.:|..:|.:|.||.:||...||||.:
Mouse   211 ATGCLPFNGYSYEAIKQKIIAGKYPRSFSLSPELWEVIAKLLTVNPGERPTVHDIARFKWLKPDN 275

  Fly   278 EPDSTTSTSEHFLPLVSREQLGE--EDH----AFIIQKMINGNIASKEEILQALDKNKYNHITAT 336
            |              .|...|||  |.|    ..::..::..|   ..||.::|.:.|::.:.||
Mouse   276 E--------------ASPASLGENIESHPDPSIMVLMGVMGYN---PGEIRESLREKKFDQVMAT 323

  Fly   337 YFLLAEL-----------------RLRRRREELAQKQRLLNDASMKVGDASRKLVPEKPSPTEAQ 384
            |.:|.:.                 |:.|..|...:.|..:..||.....::..|    |:.:|:.
Mouse   324 YLMLKQQSAWENKTTKKPDPRLCDRMLRSTEPTIKNQTAVRRASSVPTHSTFSL----PNESESL 384

  Fly   385 KGG--VPISINVTPAAQFANDGGKPDKRSRKCSIVREEDEEESATECTAVGNELKVTSSSRREAF 447
            :.|  ..:|.::.|              :|.|.       .|..|...::..:|...:..||..:
Mouse   385 EKGKRTTMSHSMPP--------------TRNCF-------NEETTPLHSICPQLVQKAHYRRSIW 428

  Fly   448 SDSPFSRSIHERSSSEPGNQTKGEQIANSGVPSHS-RTKIVVSVDATLAHKLKQMEK-----SAK 506
            .::..|.:..|.|:        ||.:.:..:..|: :|.:.||...:...|.|...:     ...
Mouse   429 GETEISDTSEESST--------GESLEHPSLKIHTLQTSMGVSKAGSTYSKSKGSSQCVSSHHTS 485

  Fly   507 IDEDTLSGL---------------KELEIGKLKPLPSSSKNPVLTHRRTKLNKIRTPSCSSSEAS 556
            ::||...|.               :|..:|:|..:.::....::.      .::.:|..|..||.
Mouse   486 VEEDQCEGTNISREINPPLSPVSPQENLMGQLHIVTTAGSMDIMN------TQVTSPPFSRKEAK 544

  Fly   557 DDDTKTRNKKKINKFVGDTPVRFRMHRRDSHDDSSDS 593
                            |:.|.   :.:|:|...|.::
Mouse   545 ----------------GEGPA---IQQRESRPSSPNT 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snrk	NP_610942.2	STKc_SNRK	16..273	CDD:270976	102/254 (40%)
		UBA_SNRK	296..338	CDD:270524	12/47 (26%)
Gm14147	XP_355352.1	STKc_AMPK-like	23..270	CDD:270905	102/253 (40%)
		UBA_MARK_Par1	290..328	CDD:270522	8/40 (20%)