Protein Alignment CG8485 and Sik2

DIOPT Version :9

• Sequence 1: NP_610942.2
• Gene: CG8485 / 36579
• FlyBaseID: FBgn0033915
• Length: 860
• Species: Drosophila melanogaster
• Sequence 2: NP_569972.1
• Gene: Sik2 / 31170
• FlyBaseID: FBgn0025625
• Length: 1398
• Species: Drosophila melanogaster
• Alignment Length: 1014
• Identity: 237/1014 - (23%)
• Similarity: 394/1014 - (38%)
• Gaps: 333/1014 - (32%)

  Fly     9 GGVSDGKI--------AGLYDLEETLGSGHFAVVKLARHVFTGAKVAVKVVDKTKLDDVSKAHLF 65
            ||:|...:        .|.||:|.|:|.|:|||||||||..|..:||:|::||::||..:...::
  Fly   122 GGISGKDLLKLKEPMRVGFYDIERTIGKGNFAVVKLARHRITKNEVAIKIIDKSQLDQTNLQKVY 186

  Fly    66 QEVRCMKLVQHPNVVRLYEVIDTQTKLYLVLELGDGGDLYDYIMKHDSGLSEELARKYFRQILRA 130
            :||..||.::||::::||:|::|:..:|:|.|....|:::|||.|: ..:||..||..|.||:.|
  Fly   187 REVEIMKRLKHPHIIKLYQVMETKNMIYIVSEYASQGEIFDYIAKY-GRMSESAARFKFWQIISA 250

  Fly   131 ITYCHQLHVVHRDLKPENVVFFEKLGLVKLTDFGFSNKFLPGQKLETFCGSLAYSAPEILLGDSY 195
            :.|||:..:||||||.||::....:. :|:.||||||.|.||:.|.|:|||..|:|||:..|..|
  Fly   251 VEYCHKKGIVHRDLKAENLLLDLNMN-IKIADFGFSNHFKPGELLATWCGSPPYAAPEVFEGKQY 314

  Fly   196 DAPAVDIWSLGVILYMLVCGQAPFEKANDSETLTMIMDCKYTVPSHVSTDCRDLIASMLVRDPKK 260
            ..|.:|||||||:||:||||..||:.:........::..::.:|..:|::|..||..|||.:|.:
  Fly   315 TGPEIDIWSLGVVLYVLVCGALPFDGSTLQSLRDRVLSGRFRIPFFMSSECEHLIRRMLVLEPTR 379

  Fly   261 RATVEEIASSAWLKPIDEPDSTTSTSEHFLPLVSREQLGEEDHAFIIQKMINGNIASKEEILQ-- 323
            |.|:::|....|:.|        ...||.  |:::..||.|...         ::...|:||:
  Fly   380 RYTIDQIKRHRWMCP--------ELLEHV--LIAKYNLGAERQT---------SVEPSEDILRIM 425

  Fly   324 -------------ALDKNKYNHITATYFLLAELRLRRRREE--------LA-------------- 353
                         :|.||.|:|:.|.|.||.: |:..::|:        ||
  Fly   426 AEYVGIGSDKTRASLKKNTYDHVAAIYLLLQD-RVSHKKEQSNGLGASALASSTSASRMIYSSRN 489

  Fly   354 ----------QKQRLLNDASMKVGDASRK------------------LVPEKPSP---------- 380
                      |:.:.::.:|:...|...|                  ..|..|.|
  Fly   490 DHQPTQQQSQQQSKTISTSSILAKDQCHKRLSRHQTVLMSERNAHAGATPTVPDPGPGYYAKYGP 554

  Fly   381 ---------------------TEAQKGGVPISINVTPAAQFANDG-------------------- 404
                                 .|....|:|:.:..||....|:..
  Fly   555 LQLPLPLTGHSHLTGYLNGGGVEVDASGIPLPMRYTPLPTAASPAPSNCSSTSSRVGRHSLSSSS 619

  Fly   405 --------------GKPDKRSRKCSIVREEDE---------------------------EESATE 428
                          ..|...:.:|   ||..|                           ::|..:
  Fly   620 PRSHRPVAISLSIDNNPSLANLRC---REMMEAGGGPVGAVGVPLASKQLHQTISEFIIKQSTED 681

  Fly   429 CTAVGNELKVTSSSRREAFSDSPFSRS----IHERSSSEPGNQTKGEQIANSGVPSHSRTKIVVS 489
            |.|    |...|::..|...|.|.:.|    :...:|:.|.:.|.|.:..::..|.....|.:
  Fly   682 CRA----LLQQSTAVAEGKDDPPKAESSVGGVPPPASTTPTSSTAGPESGSAPCPGEINGKTI-- 740

  Fly   490 VDATLAHKLKQMEKSAKIDEDTLSGLK-----ELEIGKLKPLPSSSKNPVLTHRRTKLNKIRTPS 549
                     |.|..|:..|.....|..     ..|..||  ..:..::|:...:||| .::...|
  Fly   741 ---------KTMSSSSSFDSKANLGQSFRYKMSAEASKL--FQTLQESPLPVEQRTK-RRVHVGS 793

  Fly   550 CSSSEASDDDTKTRNKKKINKFVGDTPVRFRMHRRDSHDDSSDSQDQLYPPPGSASNAGNFISKS 614
            .:.|  ..|..:..|..|.|   ||:    |..::.....||.:.:      |..::.||
  Fly   794 TNGS--GGDSGQETNDAKSN---GDS----RSEKKVLAQGSSSTDE------GCETDQGN----- 838

  Fly   615 GSVSGKKEGQSQYKEPNNKSDENRKSHSQKNRKQHNKDHVDKHSHAERQLADSSTATTGNSTNRR 679
                          :|.:.|.|::.|:.                      ..|..|..|.:::
  Fly   839 --------------DPGSASQESKGSNG----------------------GGSGNANGGPTSH-- 865

  Fly   680 RRIRESQSLDRI----TEAQEYEMRHRCYAESEAASSSSSSTQHIDQRYSLLSLNTSTF--SVAE 738
                .|..|.|:    |..|.::||      |.|:|||||         .:|:.:..::  |:::
  Fly   866 ----SSSDLTRLVGTTTSGQSHKMR------SYASSSSSS---------GVLAGSAGSYSKSLSQ 911

  Fly   739 TKEEYDEEADATNATDQIMNTLNAAKATLQQEQYFNNNTNLSRNFNHNHNQSIIHISSQKANGKK 803
            .......:::.:...|.:...|.:.|.:|                     .|.:..||..|....
  Fly   912 NLSRGSSKSNCSGPYDSLDFALPSGKGSL---------------------PSCMGSSSMLATPTP 955

  Fly   804 SNETPKDIYNLNSIEHIDLILEDKSL----TKAIHVTGS 838
            ::.:|..|    |.||    ..::||    ...||:.|:
  Fly   956 ASASPAGI----SSEH----SSERSLYGSHNSCIHMPGA 986

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8485	NP_610942.2	STKc_SNRK	16..273	CDD:270976	110/264 (42%)
		S_TKc	20..273	CDD:214567	109/252 (43%)
		UBA_SNRK	296..338	CDD:270524	12/56 (21%)
Sik2	NP_569972.1	STKc_SIK	140..392	CDD:270973	109/253 (43%)
		S_TKc	141..392	CDD:214567	109/252 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461612
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24343
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940