Protein Alignment Snrk and Smok

DIOPT Version :10

• Sequence 1: NP_610942.2
• Gene: Snrk / 36579
• FlyBaseID: FBgn0033915
• Length: 860
• Species: Drosophila melanogaster
• Sequence 2: NP_001094414.1
• Gene: Smok / 290818
• RGDID: 1562638
• Length: 654
• Species: Rattus norvegicus
• Alignment Length: 722
• Identity: 196/722 - (27%)
• Similarity: 309/722 - (42%)
• Gaps: 179/722 - (24%)

  Fly    20 YDLEETLGSGHFAVVKLARHVFTGAKVAVKVVDKTKLDDVSKAHLFQEVRCMKLVQHPNVVRLYE 84
            |.:..:||.|.|..||||.|:.|..|||:||:.|:..:.:.|:    |:..||.:.||::::|..
  Rat    24 YRILASLGQGGFGEVKLASHLLTQTKVAIKVLPKSNKNLLLKS----EIEIMKSLDHPHIIKLLH 84

  Fly    85 VIDTQTKLYLVLELGDGGDLYDYIMKHDSG-LSEELARKYFRQILRAITYCHQLHVVHRDLKPEN 148
            :|||...:::|||...||:|...|  .|.| |.||...:.|||::.|:.||||..::|||:||||
  Rat    85 IIDTNENIFIVLEHAVGGELLTRI--EDFGYLPEEECNRLFRQMVLALQYCHQRGIIHRDIKPEN 147

  Fly   149 VVFFEKLGLVKLTDFGFSNKFLPGQKLETFCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLV 213
            ::...| |.|||:|||.|.|.:.||||.|.||:|.|.|||:...:.||..|:|:|||||:||.:.
  Rat   148 ILLDHK-GNVKLSDFGLSTKIVMGQKLTTLCGTLPYCAPELFNLNGYDGQAIDVWSLGVVLYYMA 211

  Fly   214 CGQAPFEKANDSETLTMIMDCKYTVPSHVSTDCRDLIASMLVRDPKKRATVEEIASSAWLKPIDE 278
            .|..||:..........|:..:|:|...:|.|..|:||.:|..:|::|..|.||....|||..:|
  Rat   212 TGCLPFQGFTYQAIKQKILSGRYSVNFRLSPDLWDVIAKLLTVNPRERPRVHEILRFNWLKNENE 276

  Fly   279 PDSTT---STSEHFLP--LVSREQLGEEDHAFIIQKMINGNIASKEEILQALDKNKYNHITATYF 338
            ...::   :|..|..|  ||....:|.|                :.:|.::|.:.|::.:.|||.
  Rat   277 VSPSSLGGNTDSHPDPTILVMMGDMGYE----------------QGQIRESLRERKFDQVMATYL 325

  Fly   339 LLAELRLRRRREELAQKQRLLNDASMKVGDASRKLVPEKPSPTEAQKGGVPISINVTPAAQFAND 403
            :|        ||:...:     |.|:|.           |.||:.             |....:.
  Rat   326 ML--------REKACSE-----DKSIKT-----------PHPTQC-------------AQTLKST 353

  Fly   404 GGKPDKRS--RKCSIVREEDEEESATECTA--VGNELKVTSSSRREAFSDS--PFSRSIHERSSS 462
            |...:|::  |:.|         |....|.  :.::|:..:..:|.....:  |.....::..|.
  Rat   354 GSTTEKQTTLRRGS---------SLPTLTTFYLPSKLESLNKEKRTTMRHTMPPNLNCFNKSESL 409

  Fly   463 EPGNQTKGEQIANSGVPSHSRTKIVVSVDATLAHKLKQMEKSAKIDEDTLSGLKELEIGKLKPLP 527
            ..|.:|         :.||           |::..|....||..:::...:.::.       .:|
  Rat   410 NKGRRT---------IVSH-----------TISPTLNCFNKSESLNKGKRTIVRH-------TMP 447

  Fly   528 SSSKNPVLTHRR--TKLNKIRTPSCSSSEASDDDTKTRNKKKINKFVGDTPVRFRMHRRDSHDDS 590
            ....:||   ||  .:|:|    |.....||:|.:| ||                         |
  Rat   448 PKKTSPV---RRICPRLHK----SFGMGSASEDSSK-RN-------------------------S 479

  Fly   591 SDSQDQLYPPPGSASNAGNFIS--KSGSVSGKKEG-------------QSQYKE---PNNKSD-- 635
            ||       |..:..::.:|:|  |.||...|::.             :.|||.   |:.|.:
  Rat   480 SD-------PSLTIFSSQSFMSAFKYGSTYSKRKAFLQCILHYHASQEEDQYKTTIIPSGKLNTT 537

  Fly   636 --ENRKSHSQKNRKQHN---KDHVDKHSHAERQLADSSTATTGNSTNRRRRIRESQSLDRITEAQ 695
              .|.....|.....||   ...||..:..|:....|:|||.|...    .|:|.:|:.....|.
  Rat   538 VPPNSLQEDQPTGHLHNVLTAGAVDNRNLQEKSPPFSTTATKGEGP----AIKERESIPSSPRAP 598

  Fly   696 EYEMRHR 702
            ..:.|.|
  Rat   599 REQFRGR 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snrk	NP_610942.2	STKc_SNRK	16..273	CDD:270976	104/253 (41%)
		UBA_SNRK	296..338	CDD:270524	7/41 (17%)
Smok	NP_001094414.1	STKc_AMPK-like	23..270	CDD:270905	104/252 (41%)
		UBA_MARK_Par1	290..329	CDD:270522	12/62 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	336..369		10/65 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	563..616		12/47 (26%)