Protein Alignment Snrk and sad-1

DIOPT Version :10

• Sequence 1: NP_610942.2
• Gene: Snrk / 36579
• FlyBaseID: FBgn0033915
• Length: 860
• Species: Drosophila melanogaster
• Sequence 2: NP_001076760.1
• Gene: sad-1 / 181471
• WormBaseID: WBGene00004719
• Length: 914
• Species: Caenorhabditis elegans
• Alignment Length: 946
• Identity: 233/946 - (24%)
• Similarity: 386/946 - (40%)
• Gaps: 211/946 - (22%)

  Fly     3 LETQPVGGVSDGKIAGLYDLEETLGSGHFAVVKLARHVFTGAKVAVKVVDKTKLDDVSKAHLFQE 67
            :.|:|   |:..:..|.|.||:|||.|...:||...|..||.|||:|:|:|.||.:.....:.:|
 Worm    33 VSTRP---VAQAQYCGPYKLEKTLGKGQTGLVKTGTHCITGRKVAIKIVNKEKLSESVLQKVERE 94

  Fly    68 VRCMKLVQHPNVVRLYEVIDTQTKLYLVLELGDGGDLYDYIMKHDSGLSEELARKYFRQILRAIT 132
            :..|||::||:|:.||:|.:.:..|||:||...||:|:||:::....:|:| |||:||||:.|:.
 Worm    95 IAIMKLIEHPHVLHLYDVYENKKYLYLLLEHVSGGELFDYLVRKGRLMSKE-ARKFFRQIISALD 158

  Fly   133 YCHQLHVVHRDLKPENVVFFEKLGLVKLTDFGFSNKFLPGQKLETFCGSLAYSAPEILLGDSYDA 197
            :||..::.||||||||::..|: ..:|:.|||.::..:.|..|||.|||..|:.||::.|:.||.
 Worm   159 FCHAHNICHRDLKPENLLLDER-NNIKVADFGMASLQVEGSMLETSCGSPHYACPEVIRGEKYDG 222

  Fly   198 PAVDIWSLGVILYMLVCGQAPFEKANDSETLTMIMDCKYTVPSHVSTDCRDLIASMLVRDPKKRA 262
            ...|:||.|||||.|:.|..||:..|....|..:....:.:|..|..|.:.|:.:|:..||.||.
 Worm   223 RKADVWSCGVILYALLVGALPFDDDNLRNLLEKVKRGVFHIPHFVPADVQSLLRAMIEVDPGKRY 287

  Fly   263 TVEEIASSAWLKPIDEPD------STTSTSEHFLPLVSREQLGEEDHAFIIQKMIN--GNIASKE 319
            ::.::....|:....:.|      .:.....|.:|       ||:.....:.:.:|  |....|:
 Worm   288 SLADVFKHPWVSGTTKADPELELPMSQVVQTHVIP-------GEDSIDPDVLRHMNCLGCFKDKQ 345

  Fly   320 EILQALDKNKYNHITATYFLLAELRLRRRREE---------LAQKQRLLNDASMKVGDASR---- 371
            :::..|...|:|.....||||.:.:.||..:|         .||.    ||...|..|:||
 Worm   346 KLINELLSPKHNTEKMVYFLLLDRKRRRPAQEDDTEIVLRGAAQN----NDPPKKRTDSSRTSRY 406

  Fly   372 ---------KLVPEKP---------------SPTEAQKGGVPISINVTPAAQFANDGGKPDKRSR 412
                     .:.|.|.               ||||:.:.........:.:..::...|:...|.|
 Worm   407 PMGSIADGSPINPRKTYGRNQKSGRHSSLGGSPTESPRSSTRDLFGSSSSGSYSARAGEDRDRGR 471

  Fly   413 KCS--------IVREEDEEESATECTAVGNELKVTSSSRREAFSDSPFSRSIHERSSSEPGNQTK 469
            ..|        ..:..|.:..|.....|.:     :..|||: .||       .|.||...::.:
 Worm   472 SASRSTNSYHYYTQPVDPQTLAEAARHVRD-----AQERRES-RDS-------GRGSSRKESKDR 523

  Fly   470 GEQIANSGVPSHSRTKIVVSVDATLAHKLKQ---MEKSAKIDEDTL----SGLKELEIGKLKPLP 527
            .::.|:|     |..|...|..:::.||...   |.:|..:...|:    |....|..|..:...
 Worm   524 SDKSASS-----SSCKNDASSTSSVPHKYSPPSVMSESVVVSSSTMNSTNSSTNSLIAGNSQTSI 583

  Fly   528 SSSKNPVLTHRRTKLNKIRTPSCSSSEASDDDTKTRNKKKINKFVGDTPVRFRMHRRDSHDDS-- 590
            .|:..|    .|:|||.|:                      |.|:| ||   |.|||...:.:
 Worm   584 GSTSGP----WRSKLNNIK----------------------NSFLG-TP---RFHRRKMSNGTAE 618

  Fly   591 SDSQDQLYPPPGSASNAGNFISKSGSVSGKKEGQS----QYKEPNNKSDENRKSHSQKNRKQHN- 650
            |||:|..............|.|.:.|:|.:::...    |.|..|:...|..::..|.:...|:
 Worm   619 SDSEDSQMIDTTDLVKKSWFGSLASSMSVERDDTHCVPVQGKTLNSIKAELIRAFLQIHELSHSV 683

  Fly   651 -------------------------KDHVDKHSHAERQLADSSTAT-------TGNSTNRRRRIR 683
                                     |.:||.....::.:....|.|       ......|.:|:.
 Worm   684 VGQNCFRVEYKRGPTVGGSVFSRGIKMNVDIIPSPQQVVIAGETPTYVVQFVLLAGPVRRFKRLV 748

  Fly   684 E----------SQSLDRITEAQEYEMRHRCYAESEAASSSSSSTQHIDQRYSLLSLNTSTFSVAE 738
            |          .|..||..:| ...:|.|..::|...|:.|.|..           |.|:.::..
 Worm   749 EHLSAILQNSTQQRADRQQQA-ALMVRPRRLSDSSVGSACSDSES-----------NASSINMIA 801

  Fly   739 TKEEYDEEADATNA-----------------------TDQIMNTLNAAKATLQQEQYFNNNTNLS 780
            ...:..|...||::                       |....||.....::......:..:::.|
 Worm   802 RHSDKTETTSATSSDPYGPSPSMRSVGSGTANSYKSPTPHRRNTTAVTASSSSASNRYGPSSSSS 866

  Fly   781 RNFNHNHNQSIIHISSQKANGKKSNETPKDIYNLNS 816
            .::::|.:.|.....||::||   :..||:.|:..|
 Worm   867 GSYSNNADYSYHPEYSQRSNG---SSAPKNQYSPGS 899

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snrk	NP_610942.2	STKc_SNRK	16..273	CDD:270976	102/256 (40%)
		UBA_SNRK	296..338	CDD:270524	8/43 (19%)
sad-1	NP_001076760.1	STKc_BRSK1_2	45..298	CDD:270983	102/254 (40%)
		UBA_BRSK	327..379	CDD:270525	13/51 (25%)