Protein Alignment Snrk and unc-82

DIOPT Version :10

• Sequence 1: NP_610942.2
• Gene: Snrk / 36579
• FlyBaseID: FBgn0033915
• Length: 860
• Species: Drosophila melanogaster
• Sequence 2: NP_001255294.1
• Gene: unc-82 / 177514
• WormBaseID: WBGene00006814
• Length: 1793
• Species: Caenorhabditis elegans
• Alignment Length: 781
• Identity: 210/781 - (26%)
• Similarity: 335/781 - (42%)
• Gaps: 128/781 - (16%)

  Fly     5 TQPVGGVS----DGKIAGLYDLEETLGSGHFAVVKLA-RHVFTGAKVAVKVVDKTKLDDVSKAHL 64
            |.|:.|..    ..|....:::.:.||||.:..|.|| .|.| ..:||||::.|:.::  |||.|
 Worm   278 THPMSGAEPCSPTKKEKHRFEITKKLGSGTYGKVSLAYDHKF-DREVAVKLIKKSAIE--SKADL 339

  Fly    65 F---QEVRCMKLVQHPNVVRLYEVIDTQTKLYLVLELGDGGDLYDYIMKHDSGLSEELARKYFRQ 126
            .   :|:|.|..:.|||::::|||.:.:.|:.||:|...||:||||:.:..| |.|..||:.|||
 Worm   340 VRIRREIRIMSALNHPNIIQIYEVFENKDKIILVMEYSSGGELYDYVSRCGS-LPEAEARRIFRQ 403

  Fly   127 ILRAITYCHQLHVVHRDLKPENVVFFEKLGLVKLTDFGFSNKFLPGQKLETFCGSLAYSAPEILL 191
            |..|:.|||:..|.|||||.||:: .::....|:.|||.||.|.....|.|||||..|::|||:.
 Worm   404 ITSAVLYCHKHRVAHRDLKLENIL-LDQNNNAKIADFGLSNYFADKNLLTTFCGSPLYASPEIIN 467

  Fly   192 GDSYDAPAVDIWSLGVILYMLVCGQAPFEKANDSETLTMIMDCKYTVPSHVSTDCRDLIASMLVR 256
            |..|..|.||.||||::||.||.|..||:..:.:..:..|....|..|...||      ||||:|
 Worm   468 GTPYKGPEVDCWSLGILLYTLVYGSMPFDGRDFNRMVRQIKRGAYFEPETPST------ASMLIR 526

  Fly   257 -----DPKKRATVEEIASSAWLK-----PIDEPDSTTSTSEHFLPLVSREQLGEEDHAFIIQKMI 311
                 :|::|||:.:|||..||.     |:.:........:| .||..||           :.||
 Worm   527 NMLRVNPERRATIFDIASHWWLNLEENMPVIQELPENQIIDH-TPLTERE-----------ETMI 579

  Fly   312 NGNIASKEEILQALDKNKYNHITA-TYFLLAELRLRRRR-EELAQKQRLLNDASMKVGDASRKLV 374
            ..::|.::::..     ::.|::: |...:.:.|:||:. ||......:....:.|..:.:.|:.
 Worm   580 VQDLADEQDVFM-----EFGHLSSETRRKIEDFRIRRKEAEEFNDNSPVKPPKARKTDELTGKIS 639

  Fly   375 PEKPSPTE-AQKG--GV------PISIN----VTPAAQFANDGG--KPDKRSRKCSI-------- 416
            .|:|...: |:|.  ||      |..::    :....|..|..|  |.||.:.|.|.
 Worm   640 KEQPEEMKSAEKSLRGVKEEKEKPKVVDPNDPLERLRQIENRLGQNKKDKEAAKTSARVETVKLK 704

  Fly   417 -VREEDEEESATECTAVGNELKVTSSSRREAF---SDSPFSRSIHERSSSEPGNQTKGEQIANSG 477
             |::|...|...|...........:.||..:|   .|.| ..|..||..:.|.......:|...
 Worm   705 EVKKEKSPEQQPEDPKTARGTSKPADSRAPSFVPVKDRP-ETSEPERPRTRPHLTASAYRIETD- 767

  Fly   478 VPSHSRTKIVVSVDATLAHKLKQMEKSAKIDEDTLSGLKELEIGKLKPLPSSSKNPVLTHRRTKL 542
                       |::..:...|:|||| ..::.:.::.:|...:...:|:.......::..:...:
 Worm   768 -----------SLNMLMNQVLEQMEK-GPVNLNIIARIKAHPLYDTRPMVKELLESIIAAQPEPV 820

  Fly   543 NKIRTPSCSSSEASDDDTKTRNKKK--INKFVGDTPVRFR-MHRRDSHD-------DSSDSQDQL 597
            .|..:........|..:|.||.||:  :.:.:.:.|...| |..|..|.       |.....|::
 Worm   821 QKQTSKVVEQQTFSRQNTLTRKKKEDPLEEEIPEVPSPSRKMKERPWHSVEVGFDPDEEPEHDRM 885

  Fly   598 YPPPGSASNAGNFISKSGSVSGKKEGQSQYKEPNNKSDEN------RKSHSQKNRKQHNKDHVDK 656
              ....||||.....:..|.......:.:.|:....|...      .|..|..|.:....|..|.
 Worm   886 --QESIASNATEVTVQDTSFEDDSSDEEERKKTPVASTPKTPVLIVEKQESSTNAEDEESDEGDD 948

  Fly   657 HSHAE-RQLADSSTATTGNSTNRRRRIRESQSLDRITEAQEYEMRHRCYAESEAASSSSSSTQHI 720
            :|.|| .:||| .....|.|.::...:.|:                   .|:......|||.|.:
 Worm   949 YSDAEMEELAD-EVDKKGPSDSKLAPVVEN-------------------LEANPPPDPSSSPQFL 993

  Fly   721 D 721
            |
 Worm   994 D 994

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snrk	NP_610942.2	STKc_SNRK	16..273	CDD:270976	108/265 (41%)
		UBA_SNRK	296..338	CDD:270524	6/42 (14%)
unc-82	NP_001255294.1	STKc_NUAK	295..548	CDD:270975	108/263 (41%)