Protein Alignment Snrk and sik3

DIOPT Version :10

• Sequence 1: NP_610942.2
• Gene: Snrk / 36579
• FlyBaseID: FBgn0033915
• Length: 860
• Species: Drosophila melanogaster
• Sequence 2: XP_004916140.2
• Gene: sik3 / 100492939
• XenbaseID: XB-GENE-6042192
• Length: 1284
• Species: Xenopus tropicalis
• Alignment Length: 947
• Identity: 252/947 - (26%)
• Similarity: 413/947 - (43%)
• Gaps: 177/947 - (18%)

  Fly    18 GLYDLEETLGSGHFAVVKLARHVFTGAKVAVKVVDKTKLDDVSKAHLFQEVRCMKLVQHPNVVRL 82
            |.|:::.|:|.|:|||||||.|:.|.||||:|::||||||:.:...:|:||:.||::.||:::||
 Frog    24 GYYEIDRTIGKGNFAVVKLATHIVTRAKVAIKIIDKTKLDEENLKKIFREVQIMKMLCHPHIIRL 88

  Fly    83 YEVIDTQTKLYLVLELGDGGDLYDYIMKHDSGLSEELARKYFRQILRAITYCHQLHVVHRDLKPE 147
            |:|::|:..:|||.|...||:::|:::.| ..::|:.|||.|:||:.|:.:||..::||||||.|
 Frog    89 YQVMETERMIYLVTEYASGGEIFDHLVAH-GRMAEKEARKKFKQIVAAVHFCHCRNIVHRDLKAE 152

  Fly   148 NVVFFEKLGLVKLTDFGFSNKFLPGQKLETFCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYML 212
            |::....|. :|:.||||||:|.|||.|:|:|||..|:|||:..|..||.|.||||||||:||:|
 Frog   153 NLLLDANLN-IKIADFGFSNRFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVL 216

  Fly   213 VCGQAPFEKANDSETLTMIMDCKYTVPSHVSTDCRDLIASMLVRDPKKRATVEEIASSAWLKPID 277
            |||..||:.:........::..|:.:|..:||:|..||..|||.:|.||.::|:|....|:...:
 Frog   217 VCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLEPSKRLSMEQICKHKWMCQGE 281

  Fly   278 ---EPDSTTSTSEHFLPLVSREQLGEEDHAFIIQKMINGNIASKEEILQALDKNKYNHITATYFL 339
               |.:...:..:|......|:.|.|:    ::..|:...: .:|..||:|..:.|:|.:|.|.|
 Frog   282 QDLEFERLIAECQHVKLERQRDPLNEQ----VLLTMVEMGL-DRERTLQSLRTDAYDHYSAIYSL 341

  Fly   340 LAELRLRRRREELAQKQRLLNDASMKVGDASRKLVPEKPSPTEAQKGGVPISINVTPAAQFANDG 404
            |.: ||:|.:     ..||....|     |.|.:....|| .:|......:|||| |..|..|..
 Frog   342 LCD-RLKRHK-----TLRLPTQPS-----APRTVSYSTPS-VQADAASNTVSINV-PQVQLINPE 393

  Fly   405 GKPDKRSRKCSIVREEDEEESATECTAVGNELKVTSSSRREAFS--DSPFSRSIHERSSSEPGNQ 467
            .:..:.:...::..:|.||.|.   .|:...|    |.||....  |:.......|.....||..
 Frog   394 NQIVETNGTMTLDSDEAEEPSP---EALARYL----SMRRHTVGVPDTHNESGTDELQKIFPGFP 451

  Fly   468 TKGEQIANSGVPSHSRTKIVVSVDATLAHKLKQMEKSAKID--EDTLSGLKELEI----GKLKPL 526
            ...:||          ..:.|:.:..:.|.|..|..||.::  |.:|.....|::    |.|...
 Frog   452 RVTQQI----------PFLPVTQNTNVLHTLLPMPPSAHLEYKEQSLLQPPTLQLLNGMGPLGRR 506

  Fly   527 PSSSKNPVLTHRRTKLNKIRTPSC-----------------SSSEASDDDTKTR---NKKKINKF 571
            .|.....:..|.:..|.:.|.||.                 ||....|.:...|   |:.|.:..
 Frog   507 ASDGGANIQMHAQLLLKRPRGPSPLVTMATTVTAVTPVDEESSDGEPDQEAVQRYLANRTKRHTL 571

  Fly   572 VGDTPV---------------RFR-----------MHRRDSHDDSSDSQDQLYPPPGSASNAGNF 610
            ...:|.               .||           :||....|.::     |:.|....|....|
 Frog   572 AMTSPTAEIPPELQRQLGQQQAFRNRAWPPHLAPDLHRSMYKDSNT-----LHLPAERFSPVRRF 631

  Fly   611 -------------ISKSGSVSGKKEGQSQYKEPNNK-----SDENRKSHSQKNRKQHNKDHVDKH 657
                         :.|.|:.:...:...|..|...|     .||....|:|:....:..:|  :|
 Frog   632 SDGAATIQAFKAHLEKMGNQNSSIKQLQQECEQLQKMYGVHMDERTLEHTQQQHVMYQHEH--QH 694

  Fly   658 SHAERQLAD------------SSTATTGNS------TNRRRRIRESQSLDRITEAQEYEMRHRCY 704
            ...::|:.|            ||:.|..:.      |::.:|:|...|......|..:..|.
 Frog   695 HLLQQQIQDCIRPAQPSPPLQSSSMTPASENQPALLTHQLQRLRIQPSSPPPNPASNHLFRQ--- 756

  Fly   705 AESEAASSSSSSTQ-H---IDQRYSLLSLNTSTFSVAET--------------KEEYDEEADATN 751
            ..|....|||:..| |   ...:|..:..::|.:..:.|              :::..::.....
 Frog   757 PNSSPPPSSSAMLQTHGATSSSQYPGMPTHSSIYQPSSTGSPPPSMALPRMSIQQQQSQQQSPQQ 821

  Fly   752 ATDQIMNTLNAAKAT-----------LQQEQYFNNNTNLSRNFNHNHNQSIIHISSQKANGKKSN 805
            .|.|:....:...|:           :|.:|   ..:.:|...|::|......:|:..|.....|
 Frog   822 VTIQVQEASDLPGASRGMPIIPCANHIQMQQ---RASLMSSMGNYSHRPLSKQLSADNAEVHSLN 883

  Fly   806 E---TPKDIYNLNSIEHIDLILEDKSLTKAIHV-TGS 838
            .   :|...|:...: |..:..|......|::. |||
 Frog   884 MAHFSPSTNYDQTHL-HPHVFAEQPRPPPAVYTSTGS 919

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snrk	NP_610942.2	STKc_SNRK	16..273	CDD:270976	119/254 (47%)
		UBA_SNRK	296..338	CDD:270524	10/41 (24%)
sik3	XP_004916140.2	STKc_SIK	25..277	CDD:270973	118/253 (47%)
		UBA_SIK3	306..350	CDD:270593	15/49 (31%)