Protein Alignment Snrk and mark4

DIOPT Version :10

• Sequence 1: NP_610942.2
• Gene: Snrk / 36579
• FlyBaseID: FBgn0033915
• Length: 860
• Species: Drosophila melanogaster
• Sequence 2: XP_012824414.1
• Gene: mark4 / 100491038
• XenbaseID: XB-GENE-6042140
• Length: 681
• Species: Xenopus tropicalis
• Alignment Length: 676
• Identity: 218/676 - (32%)
• Similarity: 314/676 - (46%)
• Gaps: 176/676 - (26%)

  Fly     6 QPVGGVSDGKI-----AGLYDLEETLGSGHFAVVKLARHVFTGAKVAVKVVDKTKLDDVSKAHLF 65
            :|.|..|...:     .|.|.|..|:|.|:||.|||||||.||.:||:|::|||:|:..|...||
 Frog    32 RPPGARSRSSVPEEPHVGNYRLLRTIGKGNFAKVKLARHVLTGREVAIKIIDKTQLNPSSLQKLF 96

  Fly    66 QEVRCMKLVQHPNVVRLYEVIDTQTKLYLVLELGDGGDLYDYIMKHDSGLSEELARKYFRQILRA 130
            :|||.||.:.|||:|:|:|||:|:..|||::|...||:::||::.| ..:.|:.||..||||:.|
 Frog    97 REVRIMKGLNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVSH-GRMKEKEARAKFRQIVSA 160

  Fly   131 ITYCHQLHVVHRDLKPENVVFFEKLGLVKLTDFGFSNKFLPGQKLETFCGSLAYSAPEILLGDSY 195
            :.||||.::||||||.||:: .:....:|:.||||||:|.||.||:|||||..|:|||:..|..|
 Frog   161 VHYCHQKNIVHRDLKAENLL-LDSESNIKIADFGFSNEFTPGGKLDTFCGSPPYAAPELFQGKRY 224

  Fly   196 DAPAVDIWSLGVILYMLVCGQAPFEKANDSETLTMIMDCKYTVPSHVSTDCRDLIASMLVRDPKK 260
            :.|.||:||||||||.||.|..||:..|..|....::..||.:|.::||||..::...||.:|.|
 Frog   225 NGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCEGVLRRFLVLNPSK 289

  Fly   261 RATVEEIASSAW---------LKPIDEPDSTTSTSEHFLPLVSREQLGEEDHA--FIIQKMINGN 314
            |.|:::|.:..|         |||..||                    |||:|  ..|:.|:...
 Frog   290 RCTLDQIMNDKWMNIGFDSDDLKPYKEP--------------------EEDNADPKRIEIMLEMG 334

  Fly   315 IASKEEILQALDKNKYNHITATYFLL--------------AELRLRRRR---------------- 349
            . |:|||..||..||||.:.|||.||              :.|.|.|.|
 Frog   335 Y-SREEIKDALSSNKYNEVMATYLLLGRKPESEGGESRSDSTLSLSRSRVASDVTNGATKSSSVH 398

  Fly   350 ---EELAQKQRLLND--------------------------------ASMKVGDASRKLVPEKP- 378
               :...|:||..:|                                .|..||..||...|..|
 Frog   399 SKNQRGYQRQRRHSDFCGPAPAPSQAKRSPPGVGDDGAVGERLAPRRGSGSVGGGSRPPPPSSPM 463

  Fly   379 -----SPTEAQ-----KGGVPISINVTPAAQFANDGGK------PDKRSRKCSIVREEDEEESAT 427
                 :|.:|:     |...|.:||..|...     |:      .|:.|.:...:...|:|.|:|
 Frog   464 VSHAHNPNKAEIPEPRKEAPPTTINTPPGVM-----GRRNTYVCTDRHSSERHSLLHNDKENSST 523

  Fly   428 ECTAVGNELKVTSSSRREAFSDSPFSRSIHERSSSEPGNQT------------KGEQIANSGVPS 480
                         .||..|.  ||.::||.||||...|:..            :|:....|. |:
 Frog   524 -------------PSRPPAL--SPSTQSIAERSSLSRGSNVRSTFHGGHVRDRRGQNPPPSS-PT 572

  Fly   481 H-------SRTKIVVSVDATLAHKL--KQMEKSAKIDEDTLSG------LKELEIGKLKP---LP 527
            |       |||:...::.:.|..||  :..::|.::....::|      ........|:|   :.
 Frog   573 HPHEGLNQSRTRATSNLFSKLTSKLTRRVTDESERVWRPEVTGSYIPWNKTSANSSLLRPPRDVR 637

  Fly   528 SSSKNPVLTHRRTKLNKIRTPSCSSS 553
            .||::|.|....|.:    .|:..||
 Frog   638 RSSQHPPLQPTETSI----APNSPSS 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snrk	NP_610942.2	STKc_SNRK	16..273	CDD:270976	126/270 (47%)
		UBA_SNRK	296..338	CDD:270524	18/43 (42%)
mark4	XP_012824414.1	STKc_MARK	50..302	CDD:270974	124/253 (49%)
		UBA_MARK_Par1	323..361	CDD:270522	17/38 (45%)