Protein Alignment Snrk and nuak2

DIOPT Version :10

• Sequence 1: NP_610942.2
• Gene: Snrk / 36579
• FlyBaseID: FBgn0033915
• Length: 860
• Species: Drosophila melanogaster
• Sequence 2: NP_001121499.1
• Gene: nuak2 / 100158605
• XenbaseID: XB-GENE-5857794
• Length: 570
• Species: Xenopus tropicalis
• Alignment Length: 385
• Identity: 128/385 - (33%)
• Similarity: 200/385 - (51%)
• Gaps: 52/385 - (13%)

  Fly    20 YDLEETLGSGHFAVVKLARHVFTGAKVAVKVVDKTKL-DDVSKAHLFQEVRCMKLVQHPNVVRLY 83
            |:..||||.|.:..||.||. ..|.:||:|.:.|.:: |:....|:.:|...|..:.||:::.:|
 Frog    26 YEFLETLGKGTYGRVKRARD-SQGREVAIKSIRKDRIKDEQDMLHIRRETEIMSSLCHPHIISIY 89

  Fly    84 EVIDTQTKLYLVLELGDGGDLYDYIMKHDSGLSEELARKYFRQILRAITYCHQLHVVHRDLKPEN 148
            ||.:..:|:.:|:|....|||||||.:... ||:..||::||||:.|:.|||...:||||||.||
 Frog    90 EVFENSSKIVIVMEYASQGDLYDYISERQR-LSDHEARRFFRQIVSAVQYCHANGIVHRDLKLEN 153

  Fly   149 VVFFEKLGLVKLTDFGFSNKFLPGQKLETFCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLV 213
            ::..|... ||:.|||.||.:.....|:|:|||..|::|||:.|..|..|.||.|||||:||:||
 Frog   154 ILLDENKN-VKIADFGLSNIYNSESYLQTYCGSPLYASPEIVNGRPYVGPEVDSWSLGVLLYILV 217

  Fly   214 CGQAPFEKANDSETLTMIMDCKYTVPSHVSTDCRDLIASMLVRDPKKRATVEEIASSAWL----- 273
            .|..||:..:..:.:..|....|..|:|.|..| .||..:|:.:|::|||:.::||..|:
 Frog   218 HGCMPFDGQDYKKLVAQISSGAYKEPTHPSDAC-GLIRWLLMVNPERRATLADVASHWWVNWGYT 281

  Fly   274 KPIDEPDSTTSTSEHF------LPLV------SREQLGEED---HAFIIQKMINGNIASKEEILQ 323
            :|:.||       |||      |.:|      |...|.:.:   ..|:.|.:..|.|..:..:.:
 Frog   282 QPLTEP-------EHFKDTESPLAIVGGWLRRSSRPLWDNNSKMRCFLRQHLPGGTITRQRSLKR 339

  Fly   324 ALDKNKYNHITATYFLLAELRLRRRREELAQKQRLLNDASMKVGDASRKLVPEKPSPTEA 383
            :..:|..|....|         :..:|::.           .|..|.:|.:.:||...|:
 Frog   340 SKKENNINQGAVT---------QTPQEKIP-----------SVPPAPKKGILKKPQQRES 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snrk	NP_610942.2	STKc_SNRK	16..273	CDD:270976	103/253 (41%)
		UBA_SNRK	296..338	CDD:270524	8/44 (18%)
nuak2	NP_001121499.1	Protein Kinases, catalytic domain	22..276	CDD:473864	103/253 (41%)