Protein Alignment Opa1 and MGM1

DIOPT Version :9

• Sequence 1: NP_725369.1
• Gene: Opa1 / 36578
• FlyBaseID: FBgn0261276
• Length: 972
• Species: Drosophila melanogaster
• Sequence 2: NP_014854.2
• Gene: MGM1 / 854386
• SGDID: S000005737
• Length: 881
• Species: Saccharomyces cerevisiae
• Alignment Length: 986
• Identity: 206/986 - (20%)
• Similarity: 379/986 - (38%)
• Gaps: 313/986 - (31%)

  Fly   101 IGGGVSLSKKYEEWKDGLPNFKWLEDAMPQGERWSQFSRNLIEVGSLVKNAIEVDPKLKQLGEDK 165
            :|||::.:..|..:|        :|:|       |.|:::.::             ::|.|||..
Yeast    77 VGGGMAAAGSYIAYK--------MEEA-------SSFTKDKLD-------------RIKDLGESM 113

  Fly   166 LSEWRNWFDSRLDDAIEAADYQGVQIVETKDDLKAKTTVAALGITSDESRKK------------- 217
            ..::...|..   |..:...:.....|.|      .|.:||..:..|||:::
Yeast   114 KEKFNKMFSG---DKSQDGGHGNDGTVPT------ATLIAATSLDDDESKRQGDPKDDDDEDDDD 169

  Fly   218 YEKLQSQVETLQTEIMNVQIKYQKELEKMEKENRELRQQYLILKT--NKKTTAKKIKKSLIDMYS 280
            .:.....|:|.|.|::|                  |.:|.:.::|  ||
Yeast   170 EDDENDSVDTTQDEMLN------------------LTKQMIEIRTILNK---------------- 200

  Fly   281 EVLDELSGYDTGYTMADHLPRVVVVGDQSSGKTSVLESIAKARIFPRGSGEMMTRAPVKVTLAEG 345
              :|..|.:.|       ||.:||:|.|||||:||||||......|:|| .|:||.|:::||...
Yeast   201 --VDSSSAHLT-------LPSIVVIGSQSSGKSSVLESIVGREFLPKGS-NMVTRRPIELTLVNT 255

  Fly   346 PYH---VAQFRDSDREYDLTKESDLQDLRRDVEFRMKASVRGGKTVSNEVIAMTVKGPGLQRMVL 407
            |..   .|.| .|.|.|::   .|.::::| :...:..:|...:.||.|.|.:|:|...:..:.|
Yeast   256 PNSNNVTADF-PSMRLYNI---KDFKEVKR-MLMELNMAVPTSEAVSEEPIQLTIKSSRVPDLSL 315

  Fly   408 VDLPGIISTMTVDMASDTKDSIHQMTKHYMSNPNAIILCIQDGSVDAERSNVTDLVMQCDPLGRR 472
            |||||.|.....|...:.|..|..:.:.|::.|| |||.|....||...|:........||.|.|
Yeast   316 VDLPGYIQVEAADQPIELKTKIRDLCEKYLTAPN-IILAISAADVDLANSSALKASKAADPKGLR 379

  Fly   473 TIFVLTKVDLAEELADPDRIRKILSGKLFPMKALGYYAVVT------------------------ 513
            ||.|:||:|    |.||::.|.||:.|.:|: ::||..|:|
Yeast   380 TIGVITKLD----LVDPEKARSILNNKKYPL-SMGYVGVITKTPSSINRKHLGLFGEAPSSSLSG 439

  Fly   514 -------GRGRKDDSIDAIR-----QYEEDFFKNSKLFHRRGVIMPHQVTSRN--------LSLA 558
                   |:...:::.:.::     |:|:.:||.:|.:...     .||:::.        |.::
Yeast   440 IFSKGQHGQSSGEENTNGLKQIVSHQFEKAYFKENKKYFTN-----CQVSTKKLREKLIKILEIS 499

  Fly   559 VSDRFWKMVRETIEQQADAFKATRFNLETEWK-----------NNFPRLR--------ESGRDEL 604
            :|:.. :.....|:|:.|   .|.:..:.|:.           ||...|:        :..|:||
Yeast   500 MSNAL-EPTSTLIQQELD---DTSYLFKVEFNDRHLTPKSYLLNNIDVLKLGIKEFQEKFHRNEL 560

  Fly   605 FDKAKGEILDEVVTLSQISAKKWDDALSTKLW-----EKLSNYVFES----IY----LPAAQSGS 656
            ....:.|:..:|:           |.|:|:.|     :.||:...||    :|    |..|.||
Yeast   561 KSILRAELDQKVL-----------DVLATRYWKDDNLQDLSSSKLESDTDMLYWHKKLELASSG- 613

  Fly   657 QNSFNTMVDIKLRQWAEQALPAKSVEAGWEALQQEFISLMERSKKAQDHDGIFDQLKSAVVDEAI 721
                          ..:..:...|......|:.:|..:::| |.:.::|:.|.|.:.:..:
Yeast   614 --------------LTKMGIGRLSTMLTTNAILKELDNILE-STQLKNHELIKDLVSNTAI---- 659

  Fly   722 RRHSWEDKAIDMLRVIQLNTLEDRFVHDKQEWDSAVKFLESSVNAKLVQTEETLAQMFGPGQMRR 786
                              |.|..::.....:.::.:|..:..::  |.:.:.:||:......::
Yeast   660 ------------------NVLNSKYYSTADQVENCIKPFKYEID--LEERDWSLARQHSINLIK- 703

  Fly   787 ITHWQYLTQDQQKRRSVKNEL-DKILKNDTKHLPTLTHDELTTVRKNLQRDNVDVDTDYIRQTWF 850
                :.|.|...:.:::||.: .|.|.|...:|..         ..|||::.:.:.
Yeast   704 ----EELRQCNSRYQAIKNAVGSKKLANVMGYLEN---------ESNLQKETLGMS--------- 746

  Fly   851 PVYRKHFLQ---QALQRAKDCRKAYYLYTQQGAECEIS-----CSDVVLFWRIQQVI--KITGNA 905
                |..|:   :|:...|.|:...:.......:|..:     |.:|.|     ..:  |:|..|
Yeast   747 ----KLLLERGSEAIFLDKRCKVLSFRLKMLKNKCHSTIEKDRCPEVFL-----SAVSDKLTSTA 802

  Fly   906 LRQQVINREAR---------RLDKEIKAVLDE----FSDDEEKKGYLLTGKRVLLAEELIKVRQI 957
            :  ..:|.|..         .||:.:..:.||    |:.::.|     ..:.:    ||.|.:::
Yeast   803 V--LFLNVELLSDFFYNFPIELDRRLTLLGDEQVEMFAKEDPK-----ISRHI----ELQKRKEL 856

  Fly   958 QEKLEEFINSL 968
            .|...|.|:|:
Yeast   857 LELALEKIDSI 867

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Opa1	NP_725369.1	DLP_1	298..572	CDD:206738	92/320 (29%)
MGM1	NP_014854.2	CrfC	93..826	CDD:223771	190/910 (21%)
		DLP_1	208..468	CDD:206738	85/278 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341405
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0699
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11566
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840