Protein Alignment Opa1 and shi

DIOPT Version :10

• Sequence 1: NP_725369.1
• Gene: Opa1 / 36578
• FlyBaseID: FBgn0261276
• Length: 972
• Species: Drosophila melanogaster
• Sequence 2: NP_001259588.1
• Gene: shi / 45928
• FlyBaseID: FBgn0003392
• Length: 896
• Species: Drosophila melanogaster
• Alignment Length: 715
• Identity: 158/715 - (22%)
• Similarity: 278/715 - (38%)
• Gaps: 156/715 - (21%)

  Fly   274 SLIDMYSEVLDELSGYDTGYTMADHLPRVVVVGDQSSGKTSVLESIAKARIFPRGSGEMMTRAPV 338
            |||.:.:::.|..:  ..|..|...||::.|||.||:||:||||:.......||||| ::||.|:
  Fly     3 SLITIVNKLQDAFT--SLGVHMQLDLPQIAVVGGQSAGKSSVLENFVGKDFLPRGSG-IVTRRPL 64

  Fly   339 KVTLAEGPYHVAQFRDSDREYDLTKESDLQDLRRDVEFRMKASVRGGKTVSNEVIAMTVKGPGLQ 403
            .:.|..|.....:|.....:    |.|...::|:::|..........|.:||..|.:.|..|.:.
  Fly    65 ILQLINGVTEYGEFLHIKGK----KFSSFDEIRKEIEDETDRVTGSNKGISNIPINLRVYSPHVL 125

  Fly   404 RMVLVDLPGIISTMTVDMASDTKDSIHQMTKHYMSNPNAIILCIQDGSVDAERSNVTDLVMQCDP 468
            .:.|:||||:......|...|.:..|.||...::.....:||.:...:.|...|:...|..:.||
  Fly   126 NLTLIDLPGLTKVAIGDQPVDIEQQIKQMIFQFIRKETCLILAVTPANTDLANSDALKLAKEVDP 190

  Fly   469 LGRRTIFVLTKVDLAEELADPDRIRKILSGKLFPMKALGYYAVVTG-----RGRKDDSIDAIRQY 528
            .|.|||.|:||:||.:|..|   .|.||..||.|::. ||..||..     .||||  |......
  Fly   191 QGVRTIGVITKLDLMDEGTD---ARDILENKLLPLRR-GYIGVVNRSQKDIEGRKD--IHQALAA 249

  Fly   529 EEDFFKNSKLFHRRGVIMPHQVTSRNLSLAVSDRFWKMVRETIEQQADAFKATRFNLE---TEWK 590
            |..||    |.|.....|..::.:..|...::.:....:|:|:....|..:.....||   .|:|
  Fly   250 ERKFF----LSHPSYRHMADRLGTPYLQRVLNQQLTNHIRDTLPGLRDKLQKQMLTLEKEVEEFK 310

  Fly   591 NNFPRLRESGRDELFDKAKGEILDEVVTLSQISAKKWDDALSTKLWEKLSNYVFESIYLPAAQSG 655
            :..|     |...:..||..:::.::
  Fly   311 HFQP-----GDASIKTKAMLQMIQQL--------------------------------------- 331

  Fly   656 SQNSFNTMVDIKLRQWAEQALPAKSVEAGWEALQQEFISLMERSKKAQ----DHDGI-FDQLKSA 715
             |:.|.                 :::|....||    ::..|.|..|:    .|:.: |:.:|.|
  Fly   332 -QSDFE-----------------RTIEGSGSAL----VNTNELSGGAKINRIFHERLRFEIVKMA 374

  Fly   716 VVDEAIRRH-SWEDKAIDMLRV------IQLNTLEDRFVHDKQEWDSAVKFLESSVNAKLVQTEE 773
            ..::.:||. |:..:.|..:||      :....:..|.:...:|  ..:|.::..|....|....
  Fly   375 CDEKELRREISFAIRNIHGIRVGLFTPDMAFEAIVKRQIALLKE--PVIKCVDLVVQELSVVVRM 437

  Fly   774 TLAQMFGPGQMRRITHWQYLTQDQQKRRSVKNELDKILKNDTKHLPTLTHDELTTVRKNLQRDNV 838
            ..|:|....::|..|.....|..:|:..|.|.::..::..:..::.| .|::.... .|.|..:.
  Fly   438 CTAKMSRYPRLREETERIITTHVRQREHSCKEQILLLIDFELAYMNT-NHEDFIGF-ANAQNKSE 500

  Fly   839 DVDTDYIRQTWFPVYRK-HFLQQALQRAKDCRKA--------YYLYTQQGAECEISCSDVVLFWR 894
            :.:....||....|.|| |.:.|.|...||.:..        ::..:..|:.         .:|
  Fly   501 NANKTGTRQLGNQVIRKGHMVIQNLGIMKDIKLGRSGPLNVRFFSPSTGGSR---------PYW- 555

  Fly   895 IQQVIKITGNALRQQVINREARRLDKEIKAVLDEFSDDEEKKGYLLTGKRVLLAEELIKVRQIQE 959
                          .|:..|:          :..:.|::||:      |:.:|..:.:|:|.|::
  Fly   556 --------------FVLTSES----------ISWYKDEDEKE------KKFMLPLDGLKLRDIEQ 590

  Fly   960  959
              Fly   591  590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Opa1	NP_725369.1	DLP_1	298..572	CDD:206738	86/278 (31%)
		OPA1_C	629..972	CDD:466080	57/352 (16%)
shi	NP_001259588.1	DYNc	1..240	CDD:197491	78/247 (32%)
		Dynamin_M	210..498	CDD:460033	69/367 (19%)
		PH_dynamin	512..644	CDD:269958	20/119 (17%)
		GED	664..755	CDD:128597
		FAP	725..>855	CDD:429334