Protein Alignment Opa1 and mxd

DIOPT Version :10

• Sequence 1: NP_725369.1
• Gene: Opa1 / 36578
• FlyBaseID: FBgn0261276
• Length: 972
• Species: Drosophila melanogaster
• Sequence 2: XP_695562.6
• Gene: mxd / 360146
• ZFINID: ZDB-GENE-030721-8
• Length: 644
• Species: Danio rerio
• Alignment Length: 794
• Identity: 163/794 - (20%)
• Similarity: 307/794 - (38%)
• Gaps: 220/794 - (27%)

  Fly   239 YQKELEKMEKENRELRQQYLILKTNKKTTAK---KIKKSLIDMYSEVLDELSGYDTGYTMADHLP 300
            :|||...:|.|...::|..|..:|.|....:   .:.:: |..|.:::|.|.  ..|......||
Zfish     4 WQKEASAIEPEKEIIKQHGLRGRTRKGMEGEFHHHLDEN-IRPYIDLIDTLR--SVGVQNEVSLP 65

  Fly   301 RVVVVGDQSSGKTSVLESIAKARIFPRGSGEMMTRAPVKVTL---------AEGPYHVAQFRDSD 356
            .:||:|||||||:||||:::...: ||||| ::||.|:::.|         |...|...:.| .|
Zfish    66 TIVVIGDQSSGKSSVLEALSGVAL-PRGSG-IVTRCPLELRLRKVTGVKWKAVLTYRSVKSR-PD 127

  Fly   357 REYDLTKESDLQD---LRRDVEFRMKASVRGGKTVSNEVIAMTVKGPGLQRMVLVDLPGIISTMT 418
            ::.:..|..:.:|   :.:.|..........|..:.:::|.:.|....:..:.|:|||||:....
Zfish   128 KQGNNLKTFEFEDSSIVEKHVTDAQNELAGKGVGICDDLITLEVMSKDVCDLTLIDLPGIVRVPV 192

  Fly   419 VDMASDTKDSIHQMTKHYMSNPNAIILCIQDGSVDAERSNVTDLVMQCDPLGRRTIFVLTKVDLA 483
            .....|..|.|.::...|:.....|.|.:...::|...:....:....||.|.||:.:|||.||.
Zfish   193 AGQPEDVGDQIKRLIMKYIMKRETINLVVVPCNIDIATTEALRMAQNVDPEGIRTVAILTKPDLI 257

  Fly   484 EELADPDRIRKILSGKLFPMKALGYYAVVTGRGRK--DDSI---DAIRQYEEDFFKNSKLFHRRG 543
            ::..:.. |.|::..|:..::.  .|.:|..||::  :|.|   :|:.: |::||:|...|  |.
Zfish   258 DKGTEKG-ILKVVQNKVIHLRK--GYTMVKCRGQQQINDRITLEEALEE-EKEFFQNHDTF--RC 316

  Fly   544 VIMPHQVTSRNLSLAVSDRFWKMVRETIEQQADAFKATRFNLETEWK------------------ 590
            ::..::.|.:.|::.::......::.::::..|..|...::::.|.|
Zfish   317 LLSENKATIKCLAVKLTKDLVDHIKNSLQRVDDQVKKLLWDVKNELKECEGGPPQDPKGAKQFLI 381

  Fly   591 ------NNFPRLRESG----RDELFDKAKGEILDEVVTLSQISAKKWDDAL---------STKLW 636
                  |:......||    .:.||.:.:||.            |||:|.|         |.:|.
Zfish   382 KTIKKFNDIVTSMSSGELMLNENLFAELRGEF------------KKWNDHLEQKKSPFNYSKELM 434

  Fly   637 EK--------LSNY-VFESIYLPAAQSGSQNSFNTMVDIKLRQWAEQALPAKSVEAGWEALQQEF 692
            :|        .||| :||:|                    |:....|             |::..
Zfish   435 KKNRGRELHGFSNYKLFETI--------------------LQDHVAQ-------------LKEPA 466

  Fly   693 ISLMERSKKAQDHDGIFDQLKSAVVDEAIRRHSWEDKAIDMLRVIQLNTLEDRFVHDKQEWDSAV 757
            |:|:.::      :||..:..:..|.:..|.:       ..|:.|.:...|:  :..:|::
Zfish   467 INLLHKA------NGIIAKHLTDRVSQCFRNY-------PALQSIAMGKAEN--IQSRQQY---- 512

  Fly   758 KFLESSVNAKLVQTEETLAQMFGPGQMRRITHWQYLTQDQQKRRSVKNELDKILKNDTKHLPTLT 822
                        :||:.:::.|   .|..|.:.|                      |:..|.||
Zfish   513 ------------KTEQRISEQF---DMENIIYTQ----------------------DSVFLKTL- 539

  Fly   823 HDELTTVRKNLQR-DNVDVDTDYIRQTWFPVYRKHFLQQALQRAKDCRKAYYLYTQQGAECEISC 886
             :|:|..|.:.:. ..:|....|          .|.|:           .||....|....::..
Zfish   540 -NEITNERYSEEELPLIDKACKY----------SHMLE-----------TYYEIVAQRLTDQLPL 582

  Fly   887 SDVVLFWRIQQVIKITGNALRQQVINREARRLDKEIKAVLDEFSDDEEKKGYLLTGKRVLLAEEL 951
              :::.:.::|..:|....:...|......:|         .|.|.|      ::.||..|...|
Zfish   583 --MIIHFMLKQTAEIMSIEMLSLVDGTNVSKL---------LFEDTE------VSRKRTELRARL 630

  Fly   952 IKVRQIQEKLEEFI 965
            .::...||.|..||
Zfish   631 KRLTDAQEALNNFI 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Opa1	NP_725369.1	DLP_1	298..572	CDD:206738	75/290 (26%)
		OPA1_C	629..972	CDD:466080	60/356 (17%)
mxd	XP_695562.6	DLP_1	62..344	CDD:206738	75/290 (26%)
		Dynamin_M	264..544	CDD:460033	67/388 (17%)
		GED	564..643	CDD:470615	18/106 (17%)