Protein Alignment Opa1 and mxb

DIOPT Version :9

• Sequence 1: NP_725369.1
• Gene: Opa1 / 36578
• FlyBaseID: FBgn0261276
• Length: 972
• Species: Drosophila melanogaster
• Sequence 2: XP_009304072.1
• Gene: mxb / 360143
• ZFINID: ZDB-GENE-030721-6
• Length: 627
• Species: Danio rerio
• Alignment Length: 761
• Identity: 155/761 - (20%)
• Similarity: 302/761 - (39%)
• Gaps: 191/761 - (25%)

  Fly   246 MEKENRELRQQYLILKTNKKTTAKKIKKSLIDMYSEVLDELSGYDTGYTMADHLPRVVVVGDQSS 310
            |||.:....|||          .:||:..:     :.:|.|........:|  ||.:.|:|||||
Zfish     1 MEKMSYTFSQQY----------EEKIRPCI-----DTIDNLRSLGVEKDLA--LPAIAVIGDQSS 48

  Fly   311 GKTSVLESIAKARIFPRGSGEMMTRAPVKVTL----AEGPYHVAQFRDSDREYDLTKESDLQDLR 371
            ||:||||:::...: ||||| ::||.|:::.:    .:..:| .:....:.|.|....::::...
Zfish    49 GKSSVLEALSGVPL-PRGSG-IVTRCPLELKMIRSKEDEKWH-GRISYQNHEEDFDDPAEVEKKI 110

  Fly   372 RDVEFRMKASVRGGKTVSNEVIAMTVKGPGLQRMVLVDLPGIISTMTVDMASDTKDSIHQMTKHY 436
            |:.:..|..:   |..:|.|:|::.:....:..:.|:|||||..........:..|.|.::.:.:
Zfish   111 REAQDEMAGA---GVGISEELISLQITSANVPDLTLIDLPGIARVAVKGQPENIGDQIKRLIRMF 172

  Fly   437 MSNPNAIILCIQDGSVDAERSNVTDLVMQCDPLGRRTIFVLTKVDLAEELADPDRIRKILSGKLF 501
            ::....|.|.:...:||...:....:....||.|.||:.:|||.||.::..:...:..:.:..:.
Zfish   173 ITKQETINLVVVPCNVDIATTEALQMAQAEDPEGERTLGILTKPDLVDKGTEGTVVDIVHNEVIH 237

  Fly   502 PMKALGYYAVVTGRGRKD----DSIDAIRQYEEDFFKNSKLFHRRGVIMPHQVTSRNLSLAVSDR 562
            ..|.   |.:|..||:|:    .:::...:.|..|||:.          ||
Zfish   238 LTKG---YMIVRCRGQKEIMDQVTLNEATETESAFFKDH----------PH-------------- 275

  Fly   563 FWKMVRE---TIEQQADAFKATRFNLETEWKNNFPRLRESGRDELFD-----KAKGE-------- 611
            |.|:..|   ||.:.|:  |.| ..|....:.:.|||.|..:.:|.:     :|.|:
Zfish   276 FRKLYEEGFATIPKLAE--KLT-IELVHHIQRSLPRLEEQIQTKLAETQKELEAYGDGPPSDPAE 337

  Fly   612 ----ILDEVV-----TLSQISAKKWDDALSTKLWEKLSNYVFESIYLPAAQSGSQNSFNTMV--- 664
                .:|:|.     ||:..:.::...|....::.:|..   |..|..:....|..||...:
Zfish   338 RLSFFIDKVTAFTCDTLNLTTGEEVKSASKLLIFPELRQ---EFAYWNSFLDSSGYSFKLKIEEE 399

  Fly   665 ----DIKLRQWAEQALPAKSVEAGWEALQQEFISLMERSKKAQDHDGIFDQLKSAVVDEAIRRHS 725
                ::|.|   .:.||.......:|.|.:|.:.|:
Zfish   400 VDNYEVKYR---GRELPGFINYKTFEGLVREQMKLL----------------------------- 432

  Fly   726 WEDKAIDMLRVIQLNTLEDRFVHDKQE----WDSAVKFLESSVNAKLVQTEETLAQMFGPGQ--M 784
             |:.|:.||:.:. :.::.:|:...|.    :...:|..::.:.| :.|.:|.||:.....|  |
Zfish   433 -EEPALKMLKNVS-DMVKKKFIQLAQSSFTGFPILLKIAKTKIEA-IKQDKECLAESMLRTQFKM 494

  Fly   785 RRITHWQYLTQDQQKRRS-VKNELDKILKNDTKHLPTLT-------HDELTTVRKNLQRDNVDVD 841
            ..|.:.|..|..|...|| .|.|.|   :.||::...:|       |..|:.::.:|:
Zfish   495 ELIVYTQDGTYSQSLLRSKEKREED---EEDTENFDCMTVGIATSNHATLSEMKLHLE------- 549

  Fly   842 TDYIRQTWFPVYRKHFLQQALQRAKDCRKAYYLYTQQGAECEISCSDVVLFWRIQQVIKITGNAL 906
                                         :||:...|....:|..  |:.:..:|:.......::
Zfish   550 -----------------------------SYYMIASQRLADQIPM--VIRYLLLQEAALELQRSM 583

  Fly   907 RQQVINREARRLDKEIKAVLDEFSDDEEKKGYLLTGKRVLLAEELI 952
            .|.:.:::.  :|..:|   ::|...::::..|...||::.|:.|:
Zfish   584 LQLLQDKDG--VDDMLK---EDFDIGQKRENLLSRQKRLMKAQNLL 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Opa1	NP_725369.1	DLP_1	298..572	CDD:206738	69/284 (24%)
mxb	XP_009304072.1	DLP_1	35..307	CDD:206738	75/309 (24%)
		Dynamin_M	228..509	CDD:279383	65/348 (19%)
		GED	537..625	CDD:128597	18/131 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0699
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900