Protein Alignment Opa1 and mxa

DIOPT Version :10

• Sequence 1: NP_725369.1
• Gene: Opa1 / 36578
• FlyBaseID: FBgn0261276
• Length: 972
• Species: Drosophila melanogaster
• Sequence 2: NP_891987.2
• Gene: mxa / 360142
• ZFINID: ZDB-GENE-030721-5
• Length: 632
• Species: Danio rerio
• Alignment Length: 765
• Identity: 161/765 - (21%)
• Similarity: 304/765 - (39%)
• Gaps: 194/765 - (25%)

  Fly   246 MEKENRELRQQYLILKTNKKTTAKKIKKSLIDMYSEVLDELSGYDTGYTMADHLPRVVVVGDQSS 310
            |||.:....|||          .:||:..:     :.:|.|........:|  ||.:.|:|||||
Zfish     1 MEKLSYTFSQQY----------EEKIRPCI-----DTIDNLRSLGVEKDLA--LPAIAVIGDQSS 48

  Fly   311 GKTSVLESIAKARIFPRGSGEMMTRAPVKVTLAEGPYHVAQFRDSDREYD----LTKESDLQDLR 371
            ||:||||:::...: ||||| ::||.|:::.:       .:.:|.|:.:.    .|.|.|..| .
Zfish    49 GKSSVLEALSGVPL-PRGSG-IVTRCPLELKM-------IRTKDQDKWHGRISYKTYEEDFDD-P 103

  Fly   372 RDVEFRMKAS----VRGGKTVSNEVIAMTVKGPGLQRMVLVDLPGIISTMTVDMASDTKDSIHQM 432
            .:||.:::.:    ...|..:|.|:|::.:....:..:.|:|||||..........:..|.|.::
Zfish   104 AEVEKKIRQAQDEMAGAGVGISEELISLQITSANVPDLTLIDLPGIARVAVKGQPENIGDQIKRL 168

  Fly   433 TKHYMSNPNAIILCIQDGSVDAERSNVTDLVMQCDPLGRRTIFVLTKVDLAEELADPDRIRKILS 497
            .:.:::....|.|.:...:||...:....:....||.|.||:.:|||.||.::..:...:..:.:
Zfish   169 IRKFVTRQETINLVVVPCNVDIATTEALQMAQAEDPDGERTLGILTKPDLVDKGTEGTVVDIVHN 233

  Fly   498 GKLFPMKALGYYAVVTGRGRKD----DSIDAIRQYEEDFFKN----SKLFHRRGVIMPHQVTSRN 554
            ..:...|.   |.:|..||:|:    .:::...:.|..|||:    |||:......:|.  .:..
Zfish   234 EVIHLTKG---YMIVRCRGQKEIMDQVTLNEATETESAFFKDHPHFSKLYEEGFATIPK--LAEK 293

  Fly   555 LSLAVSDRFWKMVRETIEQQADAFKATRFNLETEWKNNFPRLRESGRDELFDKAKGEILDEVVTL 619
            |::.:.....|.: ..:|:|.:. |......|.|...|.|....:.|...|       :|:|...
Zfish   294 LTIELVHHIQKSL-PRLEEQIET-KLAETQKELEAYGNGPPSEPAARLSFF-------IDKVTAF 349

  Fly   620 SQISAK------------------------KWD-------DALSTKLWEKLSNYVFESIYLPAAQ 653
            :|....                        ||.       |:.:.|:.:::.||  |..|.....
Zfish   350 NQDMLNLTTGEDVKCTTDLLLFPELRQEFAKWSHILDRSGDSFNKKIEKEVDNY--EVKYRGREL 412

  Fly   654 SGSQN--SFNTMVDIKLRQWAEQALPAKSVEAGWEALQQEFISLMERSKKAQDHDGIFDQLKSAV 716
            .|..|  :|..:|..:::...|.||  |:::...:.::::||.|.:.|     ..|..:.||.|.
Zfish   413 PGFINYKTFEGLVRDQIKLLEEPAL--KTLKTVSDVVRKKFIQLAQCS-----FIGFPNLLKIAK 470

  Fly   717 VDEAIRRHSWEDKAIDMLRVIQLNTLEDRFVHDKQEWDSAVKFLESSVNAKLVQTEETLAQMFGP 781
            .               .:..|:||                    :.|:...:::|:
Zfish   471 T---------------KIEGIKLN--------------------KESLAESMLKTQ--------- 491

  Fly   782 GQMRRITHWQYLTQDQQKRRSVKNELDKILKNDTKH------LPTLTHDELTTVRKNLQRDNVDV 840
            .:|..|.:    :||....:|:|:..||:.:.:.:.      ||.|:..:|.|       ||
Zfish   492 FKMELIVY----SQDGTYSQSLKHAKDKLEEMEKERPQPKIKLPLLSSFDLGT-------DN--- 542

  Fly   841 DTDYIRQTWFPVYRKHFLQQALQRAKDCRKAYYLYTQQGAECEISCSDVVLFWRIQQ-VIKITGN 904
                              ...|:..:...|:||....:....:|..  |:.:..:|: .:::..|
Zfish   543 ------------------HATLREMRLHLKSYYTIASKRLADQIPM--VIRYMLLQEAALELQRN 587

  Fly   905 ALRQQVINREARRLDKE-IKAVLDEFSDDEEKKGYLLT-GKRVLLAEELI 952
            .|  |::.      ||: :..:|.|..|..:|:..||: .||::.|..|:
Zfish   588 ML--QLLQ------DKDGVDNLLKEDCDIGQKRENLLSRQKRLMKARSLL 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Opa1	NP_725369.1	DLP_1	298..572	CDD:206738	72/289 (25%)
		OPA1_C	629..972	CDD:466080	64/335 (19%)
mxa	NP_891987.2	DLP_1	35..307	CDD:206738	73/289 (25%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01055	44..51		6/6 (100%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01055	69..71		0/1 (0%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01055	145..148		2/2 (100%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01055	214..217		2/2 (100%)
		Dynamin_M	226..510	CDD:460033	62/354 (18%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01055	246..249		0/2 (0%)
		GED	542..632	CDD:460495	23/119 (19%)