Protein Alignment Opa1 and mxe

DIOPT Version :9

• Sequence 1: NP_725369.1
• Gene: Opa1 / 36578
• FlyBaseID: FBgn0261276
• Length: 972
• Species: Drosophila melanogaster
• Sequence 2: XP_005167721.2
• Gene: mxe / 337663
• ZFINID: ZDB-GENE-030131-9609
• Length: 657
• Species: Danio rerio
• Alignment Length: 786
• Identity: 162/786 - (20%)
• Similarity: 319/786 - (40%)
• Gaps: 168/786 - (21%)

  Fly   215 RKKYEKLQSQVETLQ--TEIMNVQIKYQKELEKMEKENRELRQQYLILKTNKKTTAKKIKKSLID 277
            ::.|....|..|.::  ||::|............:.|:..|.|.|          .:|::..:
Zfish     6 KRSYLSSGSHSENIKHHTELLNRNWFDMSPSGSTKGESSGLNQHY----------EEKVRPCI-- 58

  Fly   278 MYSEVLDELSGYDTGYTMADHLPRVVVVGDQSSGKTSVLESIAKARIFPRGSGEMMTRAPV---- 338
               :::|.|..  .|.....:||.:.|:|||||||:||||:::...: |||:| ::||.|:
Zfish    59 ---DLVDSLRA--LGVEKDLNLPAIAVIGDQSSGKSSVLEALSGVAL-PRGTG-IVTRCPLVLKL 116

  Fly   339 -KVTLAEGPYHVAQFRDSDREYDLTKESDLQDLRRDVEFRMKASVRGGKTVSNEVIAMTVKGPGL 402
             |:|..:..:.:..:.|..||.     .|...:.:.|.....|....|:.:|:|:|.:.::...:
Zfish   117 KKITKDKSWHGLLTYNDKIREL-----KDPAKIEKAVLNAQTALAGIGEGISHEMITLEIQSCDV 176

  Fly   403 QRMVLVDLPGIISTMTVDMASDTKDSIHQMTKHYMSNPNAIILCIQDGSVDAERSNVTDLVMQCD 467
            ..:.|:|||||....|.:...|.:..|..:.:.::.....|.|.:...::|...:....:....|
Zfish   177 PDLTLIDLPGIARVATGNQPEDIEKQIKSLIEKFIKRQETISLVVVPANIDIATTEALKMASTVD 241

  Fly   468 PLGRRTIFVLTKVDLAEELADPDRIRKILSGKLFPMKALGYYAVVTGRGRKD--DSIDAIRQYEE 530
            |.|:||:.:|||.||.:...: |.:.:.::.::.|:|.  .|.:|..||::|  |.:..:...|:
Zfish   242 PTGQRTLGILTKPDLVDRGME-DTVVRTVNNEVIPLKK--GYMIVKCRGQQDINDKLGLVEALEK 303

  Fly   531 D--FFKNSKLFHRRGVIMPHQVTSRNLSLAVSDRFWKMVRETIEQQADAFKATRFNLETEWKNNF 593
            :  ||..:  .|.|.::...:.|...|:       .::.:|.:|..|......:..||.:.:...
Zfish   304 ERRFFDEN--VHFRSLLEDRKATIPLLA-------ERLTKELVEHIAKNLPQLQNQLEMKLEKTS 359

  Fly   594 PRLRESGRDELFDKAKGEILDEVVTLSQISAKKWDDALSTKLWEKLSNYVFESIYLPAAQSGSQN 658
            ..||..|.....||      :|......:..::::|.|     |:: ....|.:..|
Zfish   360 ADLRGLGDGVPLDK------NEKSNFLIMKIRQFNDVL-----ERV-QMAEEDVEKP-------- 404

  Fly   659 SFNTMVDIKLR----QWAEQALPAKSVEAGWEALQ---QEFISLMERSKKAQDHDGIFDQLKSAV 716
              ||.|..|:|    :| ::.|.:|:::.. |.|:   ||::    ::::.::..|.   :....
Zfish   405 --NTRVFSKIRSEFVKW-KRILDSKAIKTE-ETLRDEVQEYV----KTRRGKELPGF---VNYRT 458

  Fly   717 VDEAIRRHSWE--DKAIDMLRVIQLNTLEDRFVHDKQEWDSAVKFLESS--VNAKLVQTEETLAQ 777
            .:..:::|..|  :.|:.:|:.:      ...||...:......|...|  :.|....||:.|.:
Zfish   459 FENIVKKHIAELHEPALKLLKDV------TDIVHSSVDHIVNAHFSSFSPLMRAAKDPTEDFLHE 517

  Fly   778 MFGPGQMRRITHWQYLTQDQQKRRSVKNELDKILKNDTKHLPTLTHDELTTVRK-----NLQRDN 837
            .|...:.:  .|.|:             .::||:.:.    ..|..|:|||.:.     .||..|
Zfish   518 QFQRAEEK--IHSQF-------------RMEKIVYSQ----DDLYSDQLTTAKNTLRGYGLQSPN 563

  Fly   838 VDVDTDYIRQTWFPVYRKHFLQQALQRAKDCRKAYYLYTQQGAECEISCSDVVLFWRIQQVIKIT 902
            |..|   :|:                      .||:|.:.....||...:.:.|.
Zfish   564 VSAD---VRE----------------------MAYHLTSYLTIACERLANQIPLI---------- 593

  Fly   903 GNALRQQVINREARRLDKEIKAVLDEFSDDEEKKGYLL------TGKRVLLAEELIKVRQIQEKL 961
               ::..::|:...:|...:..::.:.|     .|.||      ..||..|.|.|.:::.....|
Zfish   594 ---VQYHMLNQYISQLQNAMLGLIGKNS-----PGMLLCEDSGVARKRKDLKERLERLKSAGRVL 650

  Fly   962 EEFINS 967
            .:|::|
Zfish   651 SKFVHS 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Opa1	NP_725369.1	DLP_1	298..572	CDD:206738	72/282 (26%)
mxe	XP_005167721.2	DLP_1	73..345	CDD:206738	74/290 (26%)
		Dynamin_M	266..552	CDD:279383	66/352 (19%)
		GED	568..653	CDD:280391	19/124 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000