Protein Alignment Opa1 and shi

DIOPT Version :10

• Sequence 1: NP_725369.1
• Gene: Opa1 / 36578
• FlyBaseID: FBgn0261276
• Length: 972
• Species: Drosophila melanogaster
• Sequence 2: XP_061497779.1
• Gene: shi / 1272935
• VectorBaseID: AGAMI1_014983
• Length: 925
• Species: Anopheles gambiae
• Alignment Length: 787
• Identity: 177/787 - (22%)
• Similarity: 317/787 - (40%)
• Gaps: 166/787 - (21%)

  Fly   273 KSLIDMYSEVLDELSGYDTGYTMADHLPRVVVVGDQSSGKTSVLESIAKARIFPRGSGEMMTRAP 337
            :|||.:.:::.|..:  ..|..|...||::.|||.||:||:||||:.......||||| ::||.|
Mosquito     2 ESLIPIVNKLQDAFT--QMGVHMQLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-IVTRRP 63

  Fly   338 VKVTLAEGPYHVAQFRDSDREYDLTKESDLQDLRRDVEFRMKASVRGGKTVSNEVIAMTVKGPGL 402
            :.:.|..|.....:|.....:    |.|:.:::|:::|..........|.:||..|.:.|..|.:
Mosquito    64 LILQLINGTVEFGEFLHQKGK----KFSNFEEIRQEIEAETDRITGSNKGISNIPINLRVYSPHV 124

  Fly   403 QRMVLVDLPGIISTMTVDMASDTKDSIHQMTKHYMSNPNAIILCIQDGSVDAERSNVTDLVMQCD 467
            ..:.|:||||:......|..:|.::.|..|...::.....:||.:...:.|...|:...|..:.|
Mosquito   125 LNLTLIDLPGLTKVPIGDQPADIENQIKGMIFQFIRKETCLILAVTPANTDLANSDALKLAKEVD 189

  Fly   468 PLGRRTIFVLTKVDLAEELADPDRIRKILSGKLFPMKALGYYAVVTG-----RGRKDDSIDAIRQ 527
            |.|.|||.|:||:||.:|..|   .|.||..||.|::. ||..||..     .||||  |.|...
Mosquito   190 PQGVRTIGVITKLDLMDEGTD---ARDILENKLLPLRR-GYIGVVNRSQKDIEGRKD--IHAALA 248

  Fly   528 YEEDFFKNSKLFH----RRGV-----IMPHQVTS--RNLSLAVSDRFWKMVRETIEQQADAFKAT 581
            .|..||.:...:.    |.|.     ::..|:|:  |:...|:.||..|.:. |:|:..|.:|..
Mosquito   249 AERKFFLSHPSYRHIADRLGTPYLQKVLNQQLTNHIRDTLPALRDRLQKQML-TLEKDVDQYKHF 312

  Fly   582 R-----------FNLETEWKNNFPRLRE-SG-----RDELFDKAK-GEILDEVVTLSQISAKKWD 628
            |           ..:..:.:::|.|..| ||     .:||...|| ..|..|.:....:.....:
Mosquito   313 RPDDPSIKTKAMLQMIQQLQSDFERTIEGSGSALVNTNELSGGAKINRIFHERLRFEIVKMSCDE 377

  Fly   629 DALSTKLWEKLSNY--VFESIYLPAAQSGSQNSFNTMVDIKLRQWAEQALPAKSVEAGWEALQQE 691
            ..|..::...:.|.  :...::.|      ..:|..:|..::.|..|..|  |.|:
Mosquito   378 KELRREISFAIRNIHGIRVGLFTP------DMAFEAIVKKQISQLKEPIL--KCVD--------- 425

  Fly   692 FISLMERSKKAQ---DHDGIFDQLKSAVVDEAIRRH--SWEDKAIDMLRVI------QLNTLEDR 745
             ::::|.|...:   |....:.:|:.. .:..|..|  ..|.||.:.:.::      .:||..:.
Mosquito   426 -LTVLELSNVVRICTDKMARYPRLRDE-TERIITTHIRQCEQKAKEQMMLLIDYELAYMNTNHED 488

  Fly   746 FV---HDKQEWDSAVKFLESSVNAKLVQTEETLAQMFGPGQMRRITHWQYLT--------QDQQK 799
            |:   :.:.:.::|||....::.:::::......|..|..:.....:|..||        .:.:|
Mosquito   489 FIGFANAQSKTENAVKTGTRNLGSQVIRKGHMCIQNLGIMKGGSRPYWFVLTSESISWFKDEDEK 553

  Fly   800 RRSVKNELDKILKND-------TKHLPTLTHDELTTVRKNLQR--------DNVDVDTDYIRQTW 849
            .:.....||.:...|       .:|...|.:.:...|.|:.::        |:||        :|
Mosquito   554 EKKFMLPLDGLKLRDIEQGFMSRRHTFGLFNPDGRNVYKDYKQLELSCESTDDVD--------SW 610

  Fly   850 FPVYRKHFLQQALQRAKDC---RKAYYLYTQQGAECEISCSD----------------------- 888
                :..||:..:...||.   .....|..||....::|.:|
Mosquito   611 ----KASFLRAGVYPEKDTPANGDEKLLSHQQSLVDDVSKTDTEESGGESGPTGQSLDPQLERQV 671

  Fly   889 ------VVLFWRIQQVIKITGN----ALRQQVINREARRLDKEIKA----------VLDEFSDDE 933
                  |..:.||  |.|.|.:    |:...:||.....::.|:.|          :::|.:|:.
Mosquito   672 ETIRNLVESYMRI--VTKTTRDMVPKAIMMLIINNTKDFINGELLAHLYATGDQASMMEESADEA 734

  Fly   934 EKKGYLL 940
            :|:..:|
Mosquito   735 QKREEML 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Opa1	NP_725369.1	DLP_1	298..572	CDD:206738	90/289 (31%)
		OPA1_C	629..972	CDD:466080	66/397 (17%)
shi	XP_061497779.1	None