Protein Alignment Opa1 and opa1

DIOPT Version :9

• Sequence 1: NP_725369.1
• Gene: Opa1 / 36578
• FlyBaseID: FBgn0261276
• Length: 972
• Species: Drosophila melanogaster
• Sequence 2: NP_001120510.2
• Gene: opa1 / 100145638
• XenbaseID: XB-GENE-989058
• Length: 1010
• Species: Xenopus tropicalis
• Alignment Length: 974
• Identity: 504/974 - (51%)
• Similarity: 669/974 - (68%)
• Gaps: 91/974 - (9%)

  Fly    65 PARGWQMPPPSRGY----GMLVVRILRGALKLRYIVLGGAIGGGVSLSKKYEEWKDGLPN---FK 122
            |.:..::.|.|.|:    ...|.|:....|||||::||.|:|||.:..|.|::|||..|:   :|
 Frog    62 PPQKSRLCPVSYGFHAKRNFWVARLASRLLKLRYLLLGSAVGGGYTAKKTYDQWKDMFPDLNEYK 126

  Fly   123 W-----------------LEDAMPQGERWSQFSRNLIEVGSLVKNAIEVDPKLKQLGEDKLSEWR 170
            |                 |..|:|..|          |:..|:       |..::||| ..|..:
 Frog   127 WIVPDFIWELDQHIDFDKLSKALPDAE----------ELSKLL-------PDFEKLGE-SFSLLK 173

  Fly   171 NWF--------------DSRL------DDAIEAADYQ-----------GV---------QIVETK 195
            .||              |..|      :.|.:|.|.|           |:         ||.:.:
 Frog   174 GWFSAGHNLVSEVIGPSDLLLFLGPGGETAFKATDNQTFEGSEKQYKKGLLGELILLQEQIQQHE 238

  Fly   196 DDLKAKTTVAALGITSDESRKKYEKLQSQVETLQTEIMNVQIKYQKELEKMEKENRELRQQYLIL 260
            ::.:.......:| ||.:.||..:|  .:::.||.|::..|:|||:.||::||||::||:  |:|
 Frog   239 EEARRAAGNINMG-TSQQHRKVSDK--DKIDQLQEELLRTQLKYQRILERLEKENKDLRK--LVL 298

  Fly   261 -KTNKKTTAKKIKKSLIDMYSEVLDELSGYDTGYTMADHLPRVVVVGDQSSGKTSVLESIAKARI 324
             |.:|....:|:|||||||||||||.||.||..|...|||||||||||||:|||||||.||:|||
 Frog   299 QKDDKGIHQRKLKKSLIDMYSEVLDILSDYDANYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARI 363

  Fly   325 FPRGSGEMMTRAPVKVTLAEGPYHVAQFRDSDREYDLTKESDLQDLRRDVEFRMKASVRGGKTVS 389
            |||||||||||:||||||:|||:|||.|:||.||:||:||:||..||.::|.||:.||:.|:|||
 Frog   364 FPRGSGEMMTRSPVKVTLSEGPHHVAMFKDSSREFDLSKETDLAALRNEIEVRMRKSVKNGQTVS 428

  Fly   390 NEVIAMTVKGPGLQRMVLVDLPGIISTMTVDMASDTKDSIHQMTKHYMSNPNAIILCIQDGSVDA 454
            .|.|:::|||||:||||||||||:|:|:|..||.||||:|..::|.||.||||||||||||||||
 Frog   429 PETISLSVKGPGIQRMVLVDLPGVINTVTSGMAPDTKDTIFNISKAYMLNPNAIILCIQDGSVDA 493

  Fly   455 ERSNVTDLVMQCDPLGRRTIFVLTKVDLAEE-LADPDRIRKILSGKLFPMKALGYYAVVTGRGRK 518
            |||.|||||.|.||.|||||||||||||||: :|.|:||::|:.|||||||||||:|||||:|..
 Frog   494 ERSIVTDLVSQMDPQGRRTIFVLTKVDLAEKNVASPNRIQQIIEGKLFPMKALGYFAVVTGKGNS 558

  Fly   519 DDSIDAIRQYEEDFFKNSKLFHRRGVIMPHQVTSRNLSLAVSDRFWKMVRETIEQQADAFKATRF 583
            ::|||:|:.|||:||:.|.|. ::|::..||||::||||||||.|||||||:|||||||||||||
 Frog   559 NESIDSIKDYEEEFFQGSSLL-KKGMLKAHQVTTKNLSLAVSDCFWKMVRESIEQQADAFKATRF 622

  Fly   584 NLETEWKNNFPRLRESGRDELFDKAKGEILDEVVTLSQISAKKWDDALSTKLWEKLSNYVFESIY 648
            |||||||||:|||||..|:|||:|||.||||||::|:|::.|.|::.|...:||::|.:|.|:||
 Frog   623 NLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLTQVTPKHWEEILQRTMWERVSTHVIENIY 687

  Fly   649 LPAAQSGSQNSFNTMVDIKLRQWAEQALPAKSVEAGWEALQQEFISLMERSKKAQDHDGIFDQLK 713
            |||||:.:..:|||.|||||:||.::.||.|:||..||.|||||...| ..:|.::||.|||:||
 Frog   688 LPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQQEFSRFM-TEQKGKEHDDIFDKLK 751

  Fly   714 SAVVDEAIRRHSWEDKAIDMLRVIQLNTLEDRFVHDKQEWDSAVKFLESSVNAKLVQTEETLAQM 778
            .:|.:|:|:||.|.::|.|.|||||.|.||||.:.|||:||:|:.|:|.::.::|..||..:..|
 Frog   752 ESVKEESIKRHKWNEQAEDSLRVIQHNALEDRSISDKQQWDAAIHFMEDTLQSRLKDTESVIRDM 816

  Fly   779 FGPGQMRRITHWQYLTQDQQKRRSVKNELDKILKNDTKHLPTLTHDELTTVRKNLQRDNVDVDTD 843
            .||....|...|...:.||..|...|.||:|:||.:..|...|.:||:|||||||:...|:||..
 Frog   817 VGPDWKERWISWTSRSPDQHTRNETKKELEKMLKVNEDHPAYLANDEVTTVRKNLEARAVEVDPV 881

  Fly   844 YIRQTWFPVYRKHFLQQALQRAKDCRKAYYLYTQQGAECEISCSDVVLFWRIQQVIKITGNALRQ 908
            .|:.||..|||:|||:.||.....||:.:|.|.:...:.|:.|:|||||||||:::.||.|.|||
 Frog   882 LIKDTWHQVYRRHFLKSALDHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLGITANTLRQ 946

  Fly   909 QVINREARRLDKEIKAVLDEFSDDEEKKGYLLTGKRVLLAEELIKVRQIQEKLEEFINSLNQEK 972
            |:||.|.|||:|.:|.||::|::|.:||..|||||||.|||:|.|||:||||||.||.:|:|||
 Frog   947 QLINTEVRRLEKNVKEVLEDFAEDGDKKVTLLTGKRVQLAEDLKKVREIQEKLEAFIEALHQEK 1010

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Opa1	NP_725369.1	DLP_1	298..572	CDD:206738	194/274 (71%)
opa1	NP_001120510.2	DLP_1	337..611	CDD:206738	194/274 (71%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	562	1.000	Domainoid score	I234
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14618
Inparanoid	1	1.050	936	1.000	Inparanoid score	I346
OMA	1	1.010	-	-		QHG52400
OrthoDB	1	1.010	-	-		D202097at33208
OrthoFinder	1	1.000	-	-		FOG0006841
OrthoInspector	1	1.000	-	-		oto102740
Panther	1	1.100	-	-	LDO	PTHR11566
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3740
SonicParanoid	1	1.000	-	-		X4932
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110