Protein Alignment CG8468 and SLC16A7

DIOPT Version :9

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: XP_011537291.1
• Gene: SLC16A7 / 9194
• HGNCID: 10928
• Length: 504
• Species: Homo sapiens
• Alignment Length: 667
• Identity: 126/667 - (18%)
• Similarity: 218/667 - (32%)
• Gaps: 247/667 - (37%)

  Fly    43 PPDSGWAWVVMVASFLCC----------------------TVIDGIVFCSGLIQEQLMAEFGVSK 85
            |||.||.|:|:.|:|:..                      |....|.:.|.::...:.|...:.:
Human    13 PPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVMYAGGRIFE 77

  Fly    86 AYVAFVSSLL------SGCYLMAGPFVSAMANRFGFRPVTITGAIFAAICFGLSYFATSVEYLFL 144
            :::.|.|..:      ||..|  ||..|.:.|::|.|||.|.|.:...:...|:.|::||..|:|
Human    78 SFLIFTSLRIQCSFTQSGSCL--GPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYL 140

  Fly   145 IYGVLGGIGFCMVYIPAVVIIGFYFEKWRALATGVAMCGSGVGTFVFAPLTKILLKS-GWRYTLA 208
            ..|.:.|:|......||:.|||.||.:.|.:|.|:||.||.|.....||..:.|..: ||:.:..
Human   141 TMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFL 205

  Fly   209 IQGIIVLSCALFGLAFRPIQPITLSVTNEEGDEQEKKKLNGHGNTVAPTPQLHQAAFTKPLPEGR 273
            |.|.::|:..:.|...||:.|          ::...|..|..|.|
Human   206 ILGSLLLNACVAGSLMRPLGP----------NQTTSKSKNKTGKT-------------------- 240

  Fly   274 FAYSMPNSAHNTYMGASQRNHYPTAQEIFKGMNLERRPSGTAQGSKGTELKQLRKSQPTTPNGDP 338
                                                                             
Human   241 ----------------------------------------------------------------- 240

  Fly   339 QQLTFNLHKELTTVGENEEEAENDNLLETEAKPVTIQARRHTVSGRRPQDIGKRSAAAAHEAHHG 403
                                       |.::.|..|:.::.|
Human   241 ---------------------------EDDSSPKKIKTKKST----------------------- 255

  Fly   404 QSHSSSRPMYRDDIFFSGSLTRIPQYQSQTSLAYHMSVTRLPTKQDMLEDRQKGCRICPEAVRRT 468
                               ..::.:|
Human   256 -------------------WEKVNKY--------------------------------------- 262

  Fly   469 LSTMLDTTLLKSPAFMCLAFSGFLTMMGFFVPFTFLVDRAKAAGMDEQAAYGVLSGIGVVNTFAR 533
                ||.:|.|...|:.......:..:|||.|..||...||..|:||.:|..:||.:..|:.|||
Human   263 ----LDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFAR 323

  Fly   534 IVCGSLSSFPAVKP--LWLNNFALTAGGIATICSGIVINTATQWTFALFFGICIACFSALRSLIA 596
            ...|.:::...::|  .:..:||:...|:..:...:..:..:...:|:|||:.....|::.....
Human   324 PSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETL 388

  Fly   597 VELIGLEKLTNAYGFLMLFQGLAATFGSPIAGGLYVMTGSYNAAFYFAGGLI-------LLSAFL 654
            ::|:|..:.::|.|.:.:.:......|.|:||.|..:||.|...:...|.::       |:...:
Human   389 MDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAI 453

  Fly   655 CYPLTWVSRWEERRNEK 671
            .|.|....|.||...:|
Human   454 NYRLLAKERKEENARQK 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS	50..>227	CDD:119392	57/205 (28%)
		MFS	<481..658	CDD:119392	44/185 (24%)
SLC16A7	XP_011537291.1	2A0113	15..484	CDD:273325	124/665 (19%)
		MFS	20..449	CDD:119392	114/637 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145481
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm9818
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.850