Protein Alignment CG8468 and SLC16A3

DIOPT Version :9

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_001035887.1
• Gene: SLC16A3 / 9123
• HGNCID: 10924
• Length: 465
• Species: Homo sapiens
• Alignment Length: 669
• Identity: 139/669 - (20%)
• Similarity: 213/669 - (31%)
• Gaps: 279/669 - (41%)

  Fly    41 VVPPDSGWAWVVMVASFLCCTVIDGI---------VFCSGLIQEQLMAEFGVSKAYVAFVSSLLS 96
            |..||.||.|.|:..    |.||.|.         ||...|||     |||:..:..|::||:|.
Human    13 VKAPDGGWGWAVLFG----CFVITGFSYAFPKAVSVFFKELIQ-----EFGIGYSDTAWISSILL 68

  Fly    97 GCYLMAGPFVSAMANRFGFRPVTITGAIFAAICFGLSYFATSVEYLFLIYGVLGGIGFCMVYIPA 161
            ......||..|...||||.|||.:.|.:||::....:.|..|:..::|..||:.|:|..:.:.|:
Human    69 AMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPS 133

  Fly   162 VVIIGFYFEKWRALATGVAMCGSGVGTFVFAPLTKILL-KSGWRYTLAIQGIIVLSCALFGLAFR 225
            ::::..||.|.|.:|.|:|..||.|.....:||.::|. :.|||....|.|.::|:|.:.....|
Human   134 LIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAALMR 198

  Fly   226 PIQPITLSVTNEEGDEQEKKKLNGHGNTVAPTPQLHQAAFTKPLPEGRFAYSMPNSAHNTYMGAS 290
            |     |.||.:.|
Human   199 P-----LVVTAQPG--------------------------------------------------- 207

  Fly   291 QRNHYPTAQEIFKGMNLERRPSGTAQGSKGTELKQLRKSQPTTPNGDPQQLTFNLHKELTTVGEN 355
                                                        :|.|
Human   208 --------------------------------------------SGPP----------------- 211

  Fly   356 EEEAENDNLLETEAKPVTIQARRHTVSGRRPQDIGKRSAAAAHEAHHGQSHSSSRPMYRDDIFFS 420
                                                                  ||..|
Human   212 ------------------------------------------------------RPSRR------ 216

  Fly   421 GSLTRIPQYQSQTSLAYHMSVTRLPTKQDMLEDRQKGCRICPEAVRRTLSTMLDTTLLKSPAFMC 485
                                                               :||.::.:...|:.
Human   217 ---------------------------------------------------LLDLSVFRDRGFVL 230

  Fly   486 LAFSGFLTMMGFFVPFTFLVDRAKAAGMDEQAAYGVLSGIGVVNTFARIVCGSLSSFPAVKP--- 547
            .|.:..:.::|.|||..|:|..||..|:.:..|..:|:.:|.::.|||...|.::....|:|
Human   231 YAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSV 295

  Fly   548 ------LWLNNFALTAGGIATICSGIVINTATQWTFALFFGICIACFSALRSLIAVELIGLEKLT 606
                  ::.|..|..||..|....|:|:       |.:||||......||:..:.:.::|..|.:
Human   296 YLFSFSMFFNGLADLAGSTAGDYGGLVV-------FCIFFGISYGMVGALQFEVLMAIVGTHKFS 353

  Fly   607 NAYGFLMLFQGLAATFGSPIAGGLYVMTGSYNAAFYFAGG-------LILLSAFLCY------PL 658
            :|.|.::|.:.:|...|.|..|.|...|..|...|..||.       ::||..|.|.      |.
Human   354 SAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQ 418

  Fly   659 TWVSRWEERRNEKLTPLPA 677
            ..|:..||   |||...||
Human   419 PEVAAAEE---EKLHKPPA 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS	50..>227	CDD:119392	60/186 (32%)
		MFS	<481..658	CDD:119392	53/198 (27%)
SLC16A3	NP_001035887.1	2A0111	8..444	CDD:331689	139/669 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	419..438		8/19 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145534
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm9818
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.850