Protein Alignment CG8468 and SLC16A4

DIOPT Version :9

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_004687.1
• Gene: SLC16A4 / 9122
• HGNCID: 10925
• Length: 487
• Species: Homo sapiens
• Alignment Length: 628
• Identity: 140/628 - (22%)
• Similarity: 235/628 - (37%)
• Gaps: 167/628 - (26%)

  Fly    45 DSGWAWVVMVASFLCCTVIDGIVFCSGLIQEQLMAEFGVSKAYVAFVSSLLSGCYLMAGPFVSAM 109
            |.||.|::::..||....:.|:.....:.......||..:...:.::.|::|.....|||.|:.:
Human    16 DGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFCAGPLVAII 80

  Fly   110 ANRFGFRPVTITGAIFAAICFGLSYFATSVEYLFLIYGVLGGIGFCMVYIPAVVIIGFYFEKWRA 174
            .:..|.:..:|.||......:.:|.:|||:.:|.:..|:|.|:|...:|..|.|:...||:|..|
Human    81 CDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVVTTKYFKKRLA 145

  Fly   175 LATGVAMCGSGVGTFVFAPLTKILLK-SGWRYTLAIQGIIVLSCALFGLAFRPIQPITLSVTNEE 238
            |:|.:|..|.|: ||:.||.||.|:. ..|...|.:.|.|.|:.....:..|||.   :...|..
Human   146 LSTAIARSGMGL-TFLLAPFTKFLIDLYDWTGALILFGAIALNLVPSSMLLRPIH---IKSENNS 206

  Fly   239 GDEQEKKKLNGHGNTVAPTPQLHQAAFTKPLPEGRFAYSMPNSAHNTYMGASQRNHYPTAQEIFK 303
            |.:.:...|:.||      |:.|                           |::.:.:.|.:...|
Human   207 GIKDKGSSLSAHG------PEAH---------------------------ATETHCHETEESTIK 238

  Fly   304 GMNLERRPSGTAQGSKGTELKQLRKSQPTTPNGDPQQLTFNLHKELTTVGENEEEAENDNLLETE 368
            ....::         .|...|.|                        ||.:|:.|
Human   239 DSTTQK---------AGLPSKNL------------------------TVSQNQSE---------- 260

  Fly   369 AKPVTIQARRHTVSGRRPQDIGKRSAAAAHEAHHGQSHSSSRPMYRDDIFFSGSLTRIPQYQSQT 433
                                          |.::|.:.:
Human   261 ------------------------------EFYNGPNRN-------------------------- 269

  Fly   434 SLAYHMSVTRLPTKQDMLEDRQKGCRICPEAVRRTLSTMLDTTLLKSPAFMCLAFSGFLTMMGFF 498
                     ||..|.|...|:         .:..:...:.|.:|.::|.|....:|..|:.:.:|
Human   270 ---------RLLLKSDEESDK---------VISWSCKQLFDISLFRNPFFYIFTWSFLLSQLAYF 316

  Fly   499 VPFTFLVDRAKAAGMDEQAAYGVLSGIGVVNTFARIVCGSLSSFPAVKPLWLNNFALTAGGIATI 563
            :|...||.|||..|:|...|..::|..|::.|.::|:.|.::....:|....:...|...||..:
Human   317 IPTFHLVARAKTLGIDIMDASYLVSVAGILETVSQIISGWVADQNWIKKYHYHKSYLILCGITNL 381

  Fly   564 CSGIVINTATQWTFALFFGICIACFS----ALRSLIAVELIGLEKLTNAYGFLMLFQGLAATFGS 624
            .:.:    ||.:...:.:.||.|.|:    ||...:.|:|.....:....|....|.|:|...|.
Human   382 LAPL----ATTFPLLMTYTICFAIFAGGYLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGP 442

  Fly   625 PIAGGLYVMTGSYNAAFYFAGGLILLS--AFLCYPLTWVSRWE 665
            ||||.||..|.:||.:|||:|...|||  :|...||  ..||:
Human   443 PIAGWLYDYTQTYNGSFYFSGICYLLSSVSFFFVPL--AERWK 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS	50..>227	CDD:119392	50/177 (28%)
		MFS	<481..658	CDD:119392	55/182 (30%)
SLC16A4	NP_004687.1	MFS	24..477	CDD:119392	132/610 (22%)
		MFS_1	27..442	CDD:284993	114/572 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..250		10/85 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145536
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D352338at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm8478
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.850