Protein Alignment CG8468 and SLC16A5

DIOPT Version :9

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: XP_005257847.1
• Gene: SLC16A5 / 9121
• HGNCID: 10926
• Length: 545
• Species: Homo sapiens
• Alignment Length: 621
• Identity: 124/621 - (19%)
• Similarity: 204/621 - (32%)
• Gaps: 230/621 - (37%)

  Fly    45 DSGWAWVVMVASFLCCTVIDGIVFCSGLIQEQLMAEFGVSKAYVAFVSSLLSGCYLMAGPFVSAM 109
            |..|||||::|:.:...:..|...|.|:...:|..||..|.:..::..|:|:....||||..|.:
Human    49 DGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSWFPSILTAVLHMAGPLCSIL 113

  Fly   110 ANRFGFRPVTITGAIFAAICFGLSYFATSVEYLFLIYGVLGGIGFCMVYIPAVVIIGFYFEKWRA 174
            ..|||.|...:.|.:.|::....|.|:.::..|:...|.:.|:|.|..:..::.::||||.:.|.
Human   114 VGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITVLGFYFVRRRV 178

  Fly   175 LATGVAMCGSGVGTFVFAPLTKILLKS-GWRYTLAIQGIIVLSCALFGLAFRPIQPITLSVTNEE 238
            ||..:|..|..:|..::..|::.||:: |||.|..:.|.|.|.|.:.|...||:
Human   179 LANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPV----------- 232

  Fly   239 GDEQEKKKLNGHGNTVAPTPQLHQAAFTKPLPEGRFAYSMPNSAHNTYMGASQRNHYPTAQEIFK 303
                        ..:|||
Human   233 ------------ATSVAP----------------------------------------------- 238

  Fly   304 GMNLERRPSGTAQGSKGTELKQLRKSQPTTPNGDPQQLTFNLHKELTTVGENEEEAENDNLLETE 368
                              |.|:.....|.||                .:|
Human   239 ------------------ETKECPPPPPETP----------------ALG--------------- 254

  Fly   369 AKPVTIQARRHTVSGRRPQDIGKRSAAAAHEAHHGQSHSSSRPMYRDDIFFSGSLTRIPQYQSQT 433
                                                                             
Human   255 ----------------------------------------------------------------- 254

  Fly   434 SLAYHMSVTRLPTKQDMLEDRQKGCRICPEAVRRTLSTMLDTTLLKSPAFMCLAFSGFL-TMMGF 497
                                       |..|..||:...|...:|:.....|:...|.: :::||
Human   255 ---------------------------CLAACGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGF 292

  Fly   498 FVPFTFLVDRAKAAGMDEQAAYGVLSGIGVVNTFARIVCGSLSSFPAVKP--LWLNNFALTAGGI 560
            .:|..|||..|....:|||.|..::|.||..|.|.|.:.|.::..||...  .:|.:.||...|:
Human   293 PLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGL 357

  Fly   561 AT-ICSGIVINTATQWTFALFFGICIA---CFSALRSLI---AVELIGLEKLTNAYGFLMLFQGL 618
            .. :|       |....|.:..|.|:|   ..|.:.:||   .::::.:::...|.|...:..||
Human   358 TNLVC-------AASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGL 415

  Fly   619 AATFGSPIAGGLYVMTGSYNAAFYFAGGLILLSAFL 654
            |.....|:||.|...|.:::..||.: ...|:||.|
Human   416 AFLISPPLAGLLLDATNNFSYVFYMS-SFFLISAAL 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS	50..>227	CDD:119392	54/177 (31%)
		MFS	<481..658	CDD:119392	51/184 (28%)
SLC16A5	XP_005257847.1	2A0113	41..493	CDD:273325	124/621 (20%)
		MFS	54..452	CDD:119392	121/616 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145525
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm9818
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.750