Protein Alignment CG8468 and Slc16a14

DIOPT Version :9

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_082197.1
• Gene: Slc16a14 / 71781
• MGIID: 1919031
• Length: 512
• Species: Mus musculus
• Alignment Length: 672
• Identity: 156/672 - (23%)
• Similarity: 257/672 - (38%)
• Gaps: 205/672 - (30%)

  Fly    23 ENIKEENEGEEEIEEAAVVVPP---DSGWAWVVMVASFLCCTVIDGIVFCSGLIQEQLMAEFGVS 84
            |:|..:.|.:.:.:....:.|.   |.||||:::::||....:|.|.....|::..:.:.||..|
Mouse     6 EDIGYDLEDDRKAKNKKTLKPHPDIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQS 70

  Fly    85 KAYVAFVSSLLSGCYLMAGPFVSAMANRFGFRPVTITGAIFAAICFGLSYFATSVEYLFLIYGVL 149
            :...|:||||..|..|:.|||:....|..|.|...|.|.:..::.:.||.:|.:|:.||:.:||.
Mouse    71 RGLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVQSLFITFGVA 135

  Fly   150 GGIGFCMVYIPAVVIIGFYFEKWRALATGVAMCGSGVGTFVFAPLTKIL-LKSGWRYTLAIQGII 213
            .|:|..|.|:||||::|.||:|.||||.|::..|:|.|||:...|.|.| .:.|||..:.|||.:
Mouse   136 AGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMFIQGAL 200

  Fly   214 VLSCALFGLAFRPIQPITLSVTNEEGDEQEKKKLNGHGNTVAPTPQLHQAAFTKPLPEGRFAYSM 278
            .|:..:.|...||:.|               :||..       .|:..:..   .||    |||.
Mouse   201 SLNLCVCGALMRPLSP---------------EKLEN-------CPEAEEPC---ALP----AYST 236

  Fly   279 PNSAHNTYMGASQRNHYPTAQEIFKGMNLERRPSGTAQGSKGTELK----QLRKSQPTTPNGDPQ 339
            .:......:|.::..              :|||        |.|..    |.::.|..|   .|:
Mouse   237 ESVKSGGPLGMAEEQ--------------DRRP--------GNEEMVCDLQTQECQGQT---HPR 276

  Fly   340 QLTFNL--HKELTTVGENEEEAENDNLLETEAKPVTIQARRHTVSGRRPQDIGKRSAAAAHEAHH 402
            :   |:  .:.|.||.:                 :|:|.||           |.|.   .|..:.
Mouse   277 K---NVCAFRVLKTVSQ-----------------LTVQVRR-----------GFRD---WHSGYF 307

  Fly   403 GQSHSSSRPMYRDDIFFSGSLTRIPQYQSQTSLAYHMSVTRLPTKQDMLEDRQKGCRICPEAVRR 467
            |.:
Mouse   308 GTA-------------------------------------------------------------- 310

  Fly   468 TLSTMLDTTLLKSPAFMCLAFSGFLTMMGFFVPFTFLVDRAKAAGMDEQ-AAYGVLSGIGVVNTF 531
                    :|..:..|:...|........|.:||..|.:......:.|| ..:.:.|.|.:::.|
Mouse   311 --------SLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVSLYNLSEQNDTFPLTSIIAILHIF 367

  Fly   532 ARIVCGSLSSFPAVKPLW----LNNFAL-----------TAGGIATICSGIVINTATQWTFALFF 581
            .:::.|:::..|.:. :|    :.||.|           |...:|.||:              ..
Mouse   368 GKVILGAVADLPCIS-VWNVFLIANFTLVLSIFLLPLMHTYASLAVICA--------------LI 417

  Fly   582 GICIACFSALRSLIAVELIGLEKLTNAYGFLMLFQGLAATFGSPIAGGLYVMTGSYNAAFYFAG- 645
            |.....|| |..::..:|:|.|.|.||||.::...|::|..|.|.||.::.:|..|:.:||..|
Mouse   418 GFSSGYFS-LMPVVTEDLVGTEHLANAYGIIICANGISALLGPPFAGWIFDITQKYDFSFYICGL 481

  Fly   646 ----GLILLSAFLCYPLTWVSR 663
                |::.|....|..:...||
Mouse   482 LYMVGILFLLIQPCIQMIDQSR 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS	50..>227	CDD:119392	66/177 (37%)
		MFS	<481..658	CDD:119392	47/197 (24%)
Slc16a14	NP_082197.1	MFS_MCT14	35..494	CDD:340987	146/632 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835595
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	289	1.000	Inparanoid score	I2793
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.790