Protein Alignment CG8468 and kar

DIOPT Version :9

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Alignment Length: 638
• Identity: 119/638 - (18%)
• Similarity: 192/638 - (30%)
• Gaps: 245/638 - (38%)

  Fly    43 PPDSG-WAWVVMVASFLCCTVIDGIVFCSGLIQEQL---MAEFG----VSKAYVAFVSSLLSGCY 99
            |||.| .||:|||::|||..:|.|.:...|:|...|   :.:.|    .|||  |.:.:|..|..
  Fly    73 PPDGGARAWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKA--ALIGALAIGTT 135

  Fly   100 LMAGPFVSAMANRFGFRPVTITGAIFAAICFGLSYFAT-SVEYLFLIYGVLGGIGFCMVYIPAVV 163
            .:.......:.::.|.|..|..|.:.:|....||.|.| ::..|:..||::.|:|..:.|.|.:.
  Fly   136 FLFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTLA 200

  Fly   164 IIGFYFEKWRALATGVAMCGSGVGTFVFAP-LTKILLKSGWRYTLAIQGIIVLSCALFGLAFRPI 227
            |:|.||:::....:|....||.|.|.:..| |.|:|...|...||.|..::.....|....::|:
  Fly   201 ILGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFVYKPL 265

  Fly   228 QPITLSVTNEEGDEQEKKKLNGHGNTVAPTPQLHQAAFTKPLPEGRFAYSMPNSAHNTYMGASQR 292
            .|
  Fly   266 HP--------------------------------------------------------------- 267

  Fly   293 NHYPTAQEIFKGMNLERRPSGTAQGSKGTELKQLRKSQPTTPNGDPQQLTFNLHKELTTVGENEE 357
                                                 .|..|...|.:...||.
  Fly   268 -------------------------------------PPEPPKKKPGRSRINLF----------- 284

  Fly   358 EAENDNLLETEAKPVTIQARRHTVSGRRPQDIGKRSAAAAHEAHHGQSHSSSRPMYRDDIFFSGS 422
                                                                             
  Fly   285 ----------------------------------------------------------------- 284

  Fly   423 LTRIPQYQSQTSLAYHMSVTRLPTKQDMLEDRQKGCRICPEAVRRTLSTMLDTTLLKSPAFMCLA 487
                                                          |.::::..:.|...|:..|
  Fly   285 ----------------------------------------------LRSIINVEIWKRKRFVIWA 303

  Fly   488 FSGFLTMMGFFVPFTFLVDRAKAAGMDEQA-----AYGVLSGIGVVNTFARIVCGSLSSFPAVKP 547
            ....|.:.|:|||:..::...|.....|..     ..|:.||||      |::.|.::..|.|..
  Fly   304 LCVPLALFGYFVPYVHMMQFVKTTFPGEDVNLPVMCIGITSGIG------RLIFGVIADMPGVNR 362

  Fly   548 LWLNNFALTAGGIATICSGIVINTATQWTFALFFGICIACFSALRSLIAVELIGLEKLTNAYGFL 612
            ::|...:|.:.|:.|:...:..:.....:|.|..|:...||.:|...||.|:.|....|.|.|||
  Fly   363 MYLQQLSLVSIGLVTLLLPLTNSYVILVSFTLVMGLFDGCFISLLGPIAYEICGPSGATQAIGFL 427

  Fly   613 MLFQGLAATFGSPIAGGLYVMTGSYNAAFYFAGGLILLSAFLCYPLTWVSRWE 665
            :....:..|.|.|:||.::..|.||......||...||.:.|.:.:..|...|
  Fly   428 LGLSSIPLTVGPPVAGMIFDSTNSYTLPLILAGLPPLLGSSLLFLIKCVKEEE 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS	50..>227	CDD:119392	53/185 (29%)
		MFS	<481..658	CDD:119392	50/181 (28%)
kar	NP_001189213.1	MFS	81..459	CDD:119392	107/607 (18%)
		MFS_1	124..439	CDD:284993	85/544 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	72	1.000	Domainoid score	I2205
eggNOG	1	0.900	-	-		E1_KOG2504
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.891027	Normalized mean entropy	S3509
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.870