Protein Alignment CG8468 and slc16a12b

DIOPT Version :9

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_001139286.1
• Gene: slc16a12b / 449947
• ZFINID: ZDB-GENE-050522-80
• Length: 488
• Species: Danio rerio
• Alignment Length: 643
• Identity: 140/643 - (21%)
• Similarity: 232/643 - (36%)
• Gaps: 210/643 - (32%)

  Fly    41 VVPPDSGWAWVVMVASFLCCTVIDGIVFCSGLIQEQLMAEFGVSKAYVAFVSSLLSGCYLMAGPF 105
            |:|||.||.|:::...|:.......:..|..:...:....|....:..|::.||:....::..|.
Zfish    21 VLPPDGGWGWMIVAGCFVVTVCTRAVTRCISIFFVEFQMHFAKDYSGTAWIHSLVDCTTMLCAPL 85

  Fly   106 VSAMANRFGFRPVTITGAIFAAICFGLSYFATSVEYLFLIYGVLGGIGFCMVYIPAVVIIGFYFE 170
            .|.:.|:...|...|.|...|::...||.||||:|||:...|:|.|:||.:.|.||:.::|.||.
Zfish    86 GSLIGNQLSCRIAVILGGFLASVGLVLSSFATSLEYLYATLGLLTGLGFALCYTPAIAMVGIYFC 150

  Fly   171 KWRALATGVAMCGSGVGTFVFAPLTKILLKS-GWRYTLAIQGIIVLSCALFGLAFRPIQPITLSV 234
            :.:|||.|:||.|||:|||:.||:.::|::. .||..|.|.|..||:..:.|...|||      :
Zfish   151 ERKALAYGIAMSGSGIGTFILAPVVQLLIEHYSWRGALLILGGFVLNLCVCGALLRPI------I 209

  Fly   235 TNEEGDEQEKKKLNGHGNTVAPTPQLHQAAFTKPLP-EGRFAYSMPNSAHNTYMGASQRNHYPTA 298
            ..||                       :|.   ||| :....||:
Zfish   210 LKEE-----------------------EAC---PLPVDSECGYSV-------------------- 228

  Fly   299 QEIFKGMNLERRPSGTAQGSKGTELKQLRKSQPTTPNGDPQQLTFNLHKELTTVGENEEEAENDN 363
                                           :|.|.||.|
Zfish   229 -------------------------------KPPTLNGGP------------------------- 237

  Fly   364 LLETEAKPVTIQARRHTVSGRRPQDIGKRSAAAAHEAHHGQSHSSSRPMYRDDIFFSGSLTRIPQ 428
                                       .||||:
Zfish   238 ---------------------------TRSAAS-------------------------------- 243

  Fly   429 YQSQTSLAYHMSVTRLPTKQDMLEDRQKGCRICPEAVRRTLSTMLDTTLLKSPAFMCLAFSGFLT 493
                                              :|.:|...:|.:...|..|.|:.||.|..|.
Zfish   244 ----------------------------------DAKQRCFQSMQEYHFLLMPDFLVLAGSFLLL 274

  Fly   494 MMGFFVPFTFLVDRAKAAGMDEQAAYGVLSGIGVVNTFARIVCGSLSSFPAVKPLWLNNFALTAG 558
            ..|..:||.:||..|...|:..|.|..::|.:||::....|..|.|:....:|. :.|...:.|.
Zfish   275 ASGCSLPFVYLVPYALDVGVGHQHAAFLMSILGVIDIVGNITFGWLTDRRCLKK-YRNICYMFAV 338

  Fly   559 GIATICSGIVINTAT-QW--TFALFFGICIACFSALRSLIAVELIGLEKLTNAYGFLMLFQGLAA 620
            |:..:|...:....| .|  .|::.:|.....:.||..::..:::|.:.|::|.|.:.....:..
Zfish   339 GMEGLCCLFIPLLRTFVWLVPFSVLYGYFDGAYVALIPVVTSDVVGRQYLSSALGVVYFLHAVPY 403

  Fly   621 TFGSPIAGGLYVMTGSYNAAFYFAGGLILLSAFLCYPLTWVSRWEERRNEK--LTPLP 676
            ....||.|.|...||:|.|.|:.:|..::.|:.|.:.:. :.|:.:|..:|  |:.:|
Zfish   404 LVSPPIGGWLVDTTGTYTATFFLSGFALISSSLLLFSVA-IIRYCQRNQKKNSLSKIP 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS	50..>227	CDD:119392	58/177 (33%)
		MFS	<481..658	CDD:119392	48/179 (27%)
slc16a12b	NP_001139286.1	MFS	33..430	CDD:119392	126/598 (21%)
		MFS_1	37..407	CDD:284993	116/571 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578850
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm8420
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.750