Protein Alignment CG8468 and SLC16A12

DIOPT Version :9

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_998771.3
• Gene: SLC16A12 / 387700
• HGNCID: 23094
• Length: 516
• Species: Homo sapiens
• Alignment Length: 648
• Identity: 134/648 - (20%)
• Similarity: 219/648 - (33%)
• Gaps: 232/648 - (35%)

  Fly    28 ENEGEEE-------IEEAAVVVPPDSGWAWVVMVASFLCCTVIDGIVFCSGLIQEQLMAEFGVSK 85
            |..|:||       :..|....|||.||.|:::...||.......:..|..:...:....|....
Human    20 EQPGKEEKRKTMAKVNRARSTSPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDY 84

  Fly    86 AYVAFVSSLLSGCYLMAGPFVSAMANRFGFRPVTITGAIFAAICFGLSYFATSVEYLFLIYGVLG 150
            |..|::.|::....::..|..|.::|....:...:.|.:.|:....||.||||:::|:|..|||.
Human    85 AQTAWIHSIVDCVTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLT 149

  Fly   151 GIGFCMVYIPAVVIIGFYFEKWRALATGVAMCGSGVGTFVFAPLTKILLKS-GWRYTLAIQGIIV 214
            |:||.:.|.||:.::|.||.:.:|||.|:||.|||:|||:.||:.::|::. .||..|.|.|..|
Human   150 GLGFALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFV 214

  Fly   215 LSCALFGLAFRPIQPITLSVTNEEGDEQEKKKLNGHGNTVAPTPQLHQAAFTKPLPEGRFAYSMP 279
            |:..:.|...|   ||||
Human   215 LNLCVCGALMR---PITL----------------------------------------------- 229

  Fly   280 NSAHNTYMGASQRNHYPTAQEIFKGMNLERRPSGTAQGSKGTELKQLRKSQPTTPNGDPQQLTFN 344
                                                            |...|||
Human   230 ------------------------------------------------KEDHTTP---------- 236

  Fly   345 LHKELTTVGENEEEAENDNLLETEAKPVTIQARRHTVSGRRPQDIGKRSAAAAHEAHHGQSHSSS 409
                           |.:::..|:
Human   237 ---------------EQNHVCRTQ----------------------------------------- 245

  Fly   410 RPMYRDDIFFSGSLTRIPQYQSQTSLAYHMSVTRLPTKQDMLEDRQKGCRICPEAVRRTLSTMLD 474
                ::||      .|:..|.|.|                  ::..:.|..|  .:::..|.:|.
Human   246 ----KEDI------KRVSPYSSLT------------------KEWAQTCLCC--CLQQEYSFLLM 280

  Fly   475 TTLLKSPAFMCLAFSGFLTMMGFFVPFTFLVDRAKAAGMDEQAAYGVLSGIGVVNTFARIVCGSL 539
            :.      |:.||.|......|....|.:||..|.:.|:..|.|..::|.:||::....|..|
Human   281 SD------FVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAFLMSILGVIDIIGNITFG-- 337

  Fly   540 SSFPAVKPLWLNN-------------FALTAGGIATICSGIVINTATQWTFALFFGICIACFSAL 591
                     ||.:             ||:...|:..:|..::.:......|:..||.....:..|
Human   338 ---------WLTDRRCLKNYQYVCYLFAVGMDGLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTL 393

  Fly   592 RSLIAVELIGLEKLTNAYGFLMLFQGLAATFGSPIAGGLYVMTGSYNAAFYFAGGLILLSAFL 654
            ..::..|::|...|::|.|.:.....:......||||.|...||||.|||...|..::.|:.|
Human   394 IPVVTTEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSVL 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS	50..>227	CDD:119392	57/177 (32%)
		MFS	<481..658	CDD:119392	47/187 (25%)
SLC16A12	NP_998771.3	2A0111	42..481	CDD:331689	129/626 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145532
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm8478
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.750