Protein Alignment CG8468 and Mct1

DIOPT Version :10

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_477334.2
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Alignment Length: 681
• Identity: 218/681 - (32%)
• Similarity: 330/681 - (48%)
• Gaps: 91/681 - (13%)

  Fly    17 LVSKQPENIKEENEGEE-EIEEAAVVVPPDSGWAWVVMVASFLCCTVIDGIVFCSGLIQEQLMAE 80
            :|...|...|.:.:.|. |::......|||.||.|||:..||:...|.||:.:..|:...:.:..
  Fly     1 MVHGPPARRKSQQQHEACEMDMERQPTPPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDY 65

  Fly    81 FGVSKAYVAFVSSLLSGCYLMAGPFVSAMANRFGFRPVTITGAIFAAICFGLSYFATSVEYLFLI 145
            |...|.|.|:::|::.|....:||..|:..||:|.|.|||.|:|.||.|..:|.||.:|..|.:.
  Fly    66 FNEGKGYTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIIT 130

  Fly   146 YGVLGGIGFCMVYIPAVVIIGFYFEKWRALATGVAMCGSGVGTFVFAPLTKILLKS-GWRYTLAI 209
            .|...|:||.::|:||:|.:..|||..|:||||:|:||||.|||||||||:.|:.: |||..:.|
  Fly   131 IGFGTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLI 195

  Fly   210 QGIIVLSCALFGLAFRPIQ----PITLSVTNEEGDEQEKKKLNGHGNTVAPTPQLHQAAFTKPLP 270
            .|.|||:|.:||..|||::    |.|...|.......:|..:.....|.|....|      |.||
  Fly   196 IGGIVLNCIIFGAMFRPLELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPL------KVLP 254

  Fly   271 EGRFAYSMPNSAHNTYMGAS-------QRNHYPTAQEIFKGMNLERRPSGTAQGSKGTELKQLRK 328
            :.:: ..:|........|.:       ..|..|         ||....:|...| :|..|
  Fly   255 KDQY-LQLPQRTDTAVSGGALCRSNSVGHNLKP---------NLNNNSNGAVNG-QGPTL----- 303

  Fly   329 SQPTTPNGDPQQLTFNLHKELTTVGENEEEAENDNLLETEAKPVTIQARR-HTVSGRRPQDIGKR 392
               .||   ||.:.              :...||::           ||: |:.....|
  Fly   304 ---VTP---PQAVV--------------KSTSNDDI-----------ARKCHSQLQLTP------ 331

  Fly   393 SAAAAHEAHHGQSHSSSRPMYRDDIFFSGSLTRIPQY-QSQTSLAYHMS----VTRLPT------ 446
                ..:||  :..|:|..|||.|..:.|||..:|.| .|:..|:..||    :.|..:
  Fly   332 ----LRDAH--RERSASGTMYRPDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNN 390

  Fly   447 -KQDMLEDRQKGCRICPEAVRRTLSTMLDTTLLKSPAFMCLAFSGFLTMMGFFVPFTFLVDRAKA 510
             .|...|.:..||..|.:..|.|.:.|::.:|||...|:..:.|.|.|.:||.||:.::|..|:.
  Fly   391 VSQSQEEAKCCGCITCSKETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAET 455

  Fly   511 AGMDEQAAYGVLSGIGVVNTFARIVCGSLSSFPAVKPLWLNNFALTAGGIATICSGIVINTATQW 575
            ..:.:..|..::|.|||.||..||:.|.:|..|.|..|.:.|..|||.|::|....:..:..:..
  Fly   456 LKLTKTDASYLISTIGVANTVGRIILGYISDKPWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLA 520

  Fly   576 TFALFFGICIACFSALRSLIAVELIGLEKLTNAYGFLMLFQGLAATFGSPIAGGLYVMTGSYNAA 640
            .:...||..|..:..|.|:|.|:|:||:|||||:|.|:||||:|:..|.||.|.:|.:|.||..|
  Fly   521 FYCCVFGFTIGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPA 585

  Fly   641 FYFAGGLILLSAFLCYPLTWVSRWEERRNEK 671
            |..||.:|.:|..:.:.:..:.|.:.|::|:
  Fly   586 FLMAGLMIAISGLVMFAIPPLQRLQVRKSER 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS_MCT_SLC16	49..>225	CDD:340910	77/176 (44%)
		MFS	<477..658	CDD:475125	69/180 (38%)
Mct1	NP_477334.2	MFS_MCT_SLC16	34..604	CDD:340910	205/634 (32%)