Protein Alignment CG8468 and Slc16a6

DIOPT Version :10

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_001402062.1
• Gene: Slc16a6 / 303772
• RGDID: 735117
• Length: 538
• Species: Rattus norvegicus
• Alignment Length: 629
• Identity: 133/629 - (21%)
• Similarity: 224/629 - (35%)
• Gaps: 192/629 - (30%)

  Fly    44 PDSGWAWVVMVASFLCCTVIDGIVFCSGLIQEQLMAEFGVSKAYVAFVSSLLSGCYLMAGPFVSA 108
            ||.||.|||..:.|.......|::...|:....||..|..|.:.::::.|:.........|..:.
  Rat    35 PDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTI 99

  Fly   109 MANRFGFRPVTITGAIFAAICFGLSYFATSVEYLFLIYGVLGGIGFCMVYIPAVVIIGFYFEKWR 173
            :.||||.|.|.:.|.:..::....:.|:..|..:::..|::.|:|:|..::|.|.|:..||:|.|
  Rat   100 LTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRR 164

  Fly   174 ALATGVAMCGSGVGTFVFAP-LTKILLKSGWRYTLAIQGIIVLSCALFGLAFRPIQPITLSVTNE 237
            ::.|.||..|.....|.||| :|.:....||||:|...|::.|:..:.|...|||
  Rat   165 SMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPI---------- 219

  Fly   238 EGDEQEKKKLNGHGNTVAPTPQLHQAAFTKPLPEGRFAYSMPNSAHNTYMGASQRNHYPTAQEIF 302
                                                                           |.
  Rat   220 ---------------------------------------------------------------II 221

  Fly   303 KGMNLERRPSGTAQGSKGTELKQLRKSQPTTPNGDPQQLTFNLHKELTTVGENEEEAENDNLLET 367
            ||           .||.        |:.|..|..:.|.:..| .|..|::...:...|    |.|
  Rat   222 KG-----------PGSP--------KAIPLEPRREVQYMLEN-EKTRTSIDSIDSGVE----LTT 262

  Fly   368 EAKPVTIQARRHTVSGRRPQDIGKRSAAAAHEAHHGQSHSSSRPMYRDDIFFSGSLTRIPQYQSQ 432
            ..|.|..:|:|.       |::                                   |:.|.|:.
  Rat   263 SPKNVPSEAKRE-------QEV-----------------------------------RVEQQQTL 285

  Fly   433 TSLAYHMSVTRLPTKQDMLEDRQKGCRICPEAVRRTLSTMLDTTLLKSPAFMCLAFSGFLTMMGF 497
            .....| |..|.|                          :||.::||..:|:|....|....:||
  Rat   286 VVGPKH-SQKRAP--------------------------LLDFSILKDRSFICYTLFGLFATLGF 323

  Fly   498 FVPFTFLVDRAKAAGMDEQAAYGVLSGIGVVNTFARIVCGSLSSFPAVKPLWLNNFALTAGGIAT 562
            |.|..:::....:.|:....|..:||.:.:...|.||..|.:.:...::.::          |..
  Rat   324 FAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIY----------IEL 378

  Fly   563 ICSGIVINTATQWTFA----------LFFGICIACFSALRSLIAVE--LIGLEKLTNAYGFLMLF 615
            ||..::..:...:|||          :|||..:.........:..|  ::|:||:::|.|..:..
  Rat   379 ICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFI 443

  Fly   616 QGLAATFGSPIAGGLYVMTGSYNAAFY-FAGGLILLSAFLCYPL 658
            |.::...|.|:||.|...:..|:.||| .|.|:.|  |.:|..|
  Rat   444 QSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMAL--AAVCLAL 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS_MCT_SLC16	49..>225	CDD:340910	49/176 (28%)
		MFS	<477..658	CDD:475125	47/193 (24%)
Slc16a6	NP_001402062.1	MFS_MCT7	40..487	CDD:340980	129/624 (21%)