Protein Alignment CG8468 and Slc16a4

DIOPT Version :10

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_001013935.1
• Gene: Slc16a4 / 295356
• RGDID: 1359655
• Length: 500
• Species: Rattus norvegicus
• Alignment Length: 632
• Identity: 138/632 - (21%)
• Similarity: 241/632 - (38%)
• Gaps: 152/632 - (24%)

  Fly    43 PPDSGWAWVVMVASFLCCTVIDGIVFCSGLIQEQLMAEFGVSKAYVAFVSSLLSGCYLMAGPFVS 107
            |.|.||.|:|::..||....:.|:.....:.......||..:...:.::.|::|.....|||..:
  Rat    14 PLDGGWGWMVVLHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFSAGPLAA 78

  Fly   108 AMANRFGFRPVTITGAIFAAICFGLSYFATSVEYLFLIYGVLGGIGFCMVYIPAVVIIGFYFEKW 172
            .:.:.||.:..:|.|....:..:.:|.:||.:.:|.:..|:|.|:|...:|..|.|:|..||:|.
  Rat    79 IICDIFGEKTTSILGTFLVSGGYLISSWATGIPFLCVTMGLLPGLGSAFLYQVAAVVITKYFKKR 143

  Fly   173 RALATGVAMCGSGVGTFVFAPLTKILLK-SGWRYTLAIQGIIVLSCALFGLAFRPIQPITLSVTN 236
            ..|:|.:|..|.|: ||:.||.||:|:. ..|...|.:.|.|.|:.....:..||:.     :.:
  Rat   144 LGLSTAIARSGMGL-TFLLAPFTKLLIDLYDWTGALILFGAIALNLVPSSMLLRPVH-----IQS 202

  Fly   237 EEGDEQEKKKLNGHGNTVAPT-PQLHQAAFTKPLPEGRFAYSMPNSAHNTYMGASQRNHYPTAQE 300
            :...:.:.|     |:.::.| |:|.....|            ||           ||   .|||
  Rat   203 DSNSDIKNK-----GSILSATGPELSHKTET------------PN-----------RN---KAQE 236

  Fly   301 IFKGMNLERRPSGTAQGSKGTELKQLRKSQPTTPNGDPQQLTFNLHKELTTVGENEEEAENDNLL 365
            ..               .|.:.:|  :..||||               ..||.||:.|
  Rat   237 SL---------------IKDSAVK--KSGQPTT---------------TLTVLENQIE------- 262

  Fly   366 ETEAKPVTIQARRHTVSGRRPQDIGKRSAAAAHEAHHGQSHSSSRPMYRDDIFFSGSLTRIPQYQ 430
                                                    ..|:||.....:..|...|...::.
  Rat   263 ----------------------------------------EISTRPHRNRPLLMSNDKTYKKKFV 287

  Fly   431 SQTSLAYHMSVTRLPTKQDMLEDRQKGCRICPEAVRRTLSTMLDTTLLKSPAFMCLAFSGFLTMM 495
            |..                           |.|       .:||.:|.::|.|....:|..|:.:
  Rat   288 SWN---------------------------CKE-------KLLDISLFRNPFFYIFTWSFLLSQL 318

  Fly   496 GFFVPFTFLVDRAKAAGMDEQAAYGVLSGIGVVNTFARIVCGSLSSFPAVKPLWLNNFALTAGGI 560
            .:|:|...||.|||..|:|...|..::|..|:..|.::::.|.::....:|....:...|...|:
  Rat   319 AYFIPTFHLVARAKTLGIDIMDASYLVSVAGITETVSQLISGWIADQNWIKKYQYHKAYLILCGV 383

  Fly   561 ATICSGIVINTATQWTFALFFGICIACFSALRSLIAVELIGLEKLTNAYGFLMLFQGLAATFGSP 625
            ..:.:.:.........:.:||.|....:.||...:.|:|....::....|:...|.|:|...|.|
  Rat   384 TNLLAPLATTFPLLMAYTIFFAIFAGGYLALILPVLVDLSKNSRVHRFLGYASFFAGMAVLSGPP 448

  Fly   626 IAGGLYVMTGSYNAAFYFAGGLILLSAFLCYPLTWVSRWEERRNEKL 672
            |||.:|..|.:|..:|||:|...:||:...:.:....||:.::::.|
  Rat   449 IAGWIYDYTQTYVGSFYFSGTCYILSSVSLFFVPLAERWKLKQSDLL 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS_MCT_SLC16	49..>225	CDD:340910	48/176 (27%)
		MFS	<477..658	CDD:475125	47/180 (26%)
Slc16a4	NP_001013935.1	MFS_MCT5	20..486	CDD:340979	131/615 (21%)