Protein Alignment CG8468 and Slc16a1

DIOPT Version :9

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_036848.1
• Gene: Slc16a1 / 25027
• RGDID: 3690
• Length: 494
• Species: Rattus norvegicus
• Alignment Length: 619
• Identity: 126/619 - (20%)
• Similarity: 209/619 - (33%)
• Gaps: 210/619 - (33%)

  Fly    43 PPDSGWAWVVMVASFLCCTVIDGIVFCSGLIQEQLMAEFGVSKAYVAFVSSLLSGCYLMAGPFVS 107
            |||.||.|.|:|.:|:.............:..:::...|..:.:.|:::||::.......||..|
  Rat    13 PPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISS 77

  Fly   108 AMANRFGFRPVTITGAIFAAICFGLSYFATSVEYLFLIYGVLGGIGFCMVYIPAVVIIGFYFEKW 172
            .:.|::|.|||.|.|...:......:.|..:|:.|:...||:||:|......||:.:||.||.|.
  Rat    78 ILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKK 142

  Fly   173 RALATGVAMCGSGVGTFVFAPLTKILLK-SGWRYTLAIQGIIVLSCALFGLAFRPIQPITLSVTN 236
            |.||.|:||.||.|.....|||.:.... .|||.:..|.|.::|:|.:.|...|||
  Rat   143 RPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPI--------- 198

  Fly   237 EEGDEQEKKKLNGHGNTVAPTPQLHQAAFTKPLPEGRFAYSMPNSAHNTYMGASQRNHYPTAQEI 301
                                                                             
  Rat   199 ----------------------------------------------------------------- 198

  Fly   302 FKGMNLERRPSGTAQGSKGTELKQLRKSQPTTPNGDPQQLTFNLHKELTTVGENEEEAENDNLLE 366
                                               .|||            |:.|:....::|
  Rat   199 -----------------------------------GPQQ------------GKVEKLKSKESL-- 214

  Fly   367 TEAKPVTIQARRHTVSGRRPQDIGKRSAAAAHEAHHGQSHSSSRPMYRDDIFFSGSLTRIPQYQS 431
                                |:.||..|
  Rat   215 --------------------QEAGKSDA------------------------------------- 222

  Fly   432 QTSLAYHMSVTRLPTKQDMLEDRQKGCRICPEAVRRTLSTMLDTTLLKSPAFMCLAFSGFLTM-M 495
                           ..|::....||.::   :|.:|::..||.:|.....|: |..||.:.| .
  Rat   223 ---------------NTDLIGGSPKGEKL---SVFQTVNKFLDLSLFTHRGFL-LYLSGNVVMFF 268

  Fly   496 GFFVPFTFLVDRAKAAGMDEQAAYGVLSGIGVVNTFARIVCGSLSSFPAVKPLWLNNFA--LTAG 558
            |.|.|..||.:..|:.....:.:..:||.:..|:..||...|..::...::|.....||  :.|.
  Rat   269 GLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVAN 333

  Fly   559 GIATICSGIVINTATQWTFALFFGICIACFSALRSLI---AVELIGLEKLTNAYGFLMLFQGLAA 620
            |   :|..:...:.|...|.::.|:....|..|.|::   .::|:|.::.::|.|.:.:.:....
  Rat   334 G---VCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPV 395

  Fly   621 TFGSPIAGGLYVMTGSYNAAFYFAGGLILLSAFL 654
            ..|.|:.|.|..|.|.|... |:|.|:||:.|.|
  Rat   396 LLGPPLLGRLNDMYGDYKYT-YWACGVILIIAGL 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS	50..>227	CDD:119392	54/177 (31%)
		MFS	<481..658	CDD:119392	47/180 (26%)
Slc16a1	NP_036848.1	2A0113	1..462	CDD:273325	126/619 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	446..494

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339218
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.850