Protein Alignment CG8468 and mct-2

DIOPT Version :10

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_503681.2
• Gene: mct-2 / 182056
• WormBaseID: WBGene00015273
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 680
• Identity: 203/680 - (29%)
• Similarity: 298/680 - (43%)
• Gaps: 181/680 - (26%)

  Fly    18 VSKQP-----ENIKEE--------NEGEEEIEEAAVVVPPDSGWAWVVMVASFLCCTVIDGIVFC 69
            :||||     :..|:|        ...||::||...|.|||.|:.|||:.||||....:||:::.
 Worm     1 MSKQPIDGPLDAEKKEVTVAVTAAENFEEQVEEVGKVTPPDGGYGWVVVAASFLVNMAVDGVIYT 65

  Fly    70 SGLIQEQLMA-EFGVSKAYVAFVSSLLSGCYLMAGPFVSAMANRFGFRPVTITGAIFAAICFGLS 133
            .|.|...:.| :|| |.:....|.|:|:|||.:|||..|:..|.||.|.|.|.|:|.|...|.||
 Worm    66 CGKILVPIWADQFG-STSVAGAVISILTGCYYLAGPLASSFVNVFGIRSVAIAGSILATTAFLLS 129

  Fly   134 YFATSVEYLFLIYGVLGGIGFCMVYIPAVVIIGFYFEKWRALATGVAMCGSGVGTFVFA----PL 194
            .||:::..|:|::||||||||..:|:|::||:..||.|.|::|||:|:||||:||.||:    |:
 Worm   130 RFASTIWELYLLFGVLGGIGFGCMYLPSIVILSTYFAKKRSVATGIAVCGSGIGTMVFSTINGPV 194

  Fly   195 TKILLKSGWRYTLAIQGIIVLSCALFGLAFRPIQPITLSVTNEEGDEQEKKKLNGHGNTVAPTPQ 259
            .....|....:.:.: ..|.:|.:||.|.|.|     |..|..:..:..|...|..|....||.:
 Worm   195 FDYFGKDVGSFMVYL-AAIAISGSLFSLLFAP-----LKATEHQVKKVAKMVRNYEGKPEEPTQR 253

  Fly   260 LHQAAFTKPLPEGRFAYSMPNSAHNTYMGASQRNHYPTAQEIFKGMNLERRPSGTAQGSKGTELK 324
            |                                                              |:
 Worm   254 L--------------------------------------------------------------LE 256

  Fly   325 QLRKSQPTTPNGDPQQLTFNLHKELTTVGENEEEAENDNLLETEAKPVTIQARRHTVSGRRPQDI 389
            .:|                |..:||...|.|.:               |..|....||..|...:
 Worm   257 DVR----------------NDLEELNRPGHNAD---------------TFYAGNAPVSRSRSNTL 290

  Fly   390 GKRSAAAAHEAH--HGQSHSSSRPMYRDDIFFSGSLTRIPQYQSQTSLAYHMSVTRLPTKQDMLE 452
            .:::|.:| |||  |...|.:...:.:...|                           ||
 Worm   291 DRKAAESA-EAHVVHATEHHTVHHVVKKSKF---------------------------TK----- 322

  Fly   453 DRQKGCRICPEAVRRTLSTMLDTTLLKSPAFMCLAFSGFLTMMGFFVPFTFLVDRAKAAGMDEQA 517
                        .:.:|.::||..||.||:||.||.||..|::.|.|||.:|....|....|...
 Worm   323 ------------FKESLCSVLDKDLLFSPSFMTLAVSGTFTVLSFLVPFVYLALAMKQKNPDFTD 375

  Fly   518 AYGVL--SGIGVVNTFARIVCGSLSSFPAVKPLWLNNFALTAGGIATICSG---IVINTATQ-WT 576
            |...|  :.||..|...||.||.::..|.:..|.::|       :|||.:|   :.:...|: |.
 Worm   376 AELSLPVTLIGAFNIMFRIGCGMVADHPKMSALQVSN-------VATIIAGTSMLFVPFCTELWH 433

  Fly   577 FALF---FGICIACFSALRSLIAVELIGLEKLTNAYGFLMLFQGLAATFGSPIAGGLYVMTGSYN 638
            :.:|   |...:|||:||||:|.|||||:|||:||:|.||:|.|:.|..|.|||..:..:||:|:
 Worm   434 YVVFCIPFSAGVACFAALRSVICVELIGVEKLSNAFGILMVFMGIGAVVGGPIAAQIKDITGNYD 498

  Fly   639 AAFYFAGGLILLSAFLCYPLTWVSRWEERR 668
            .:||..|.:...|..:...|..:..|||.:
 Worm   499 ISFYVMGIIFAFSGVMTIRLPELKAWEESK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS_MCT_SLC16	49..>225	CDD:340910	76/180 (42%)
		MFS	<477..658	CDD:475125	73/189 (39%)
mct-2	NP_503681.2	MFS_MCT_SLC16	45..519	CDD:340910	184/625 (29%)