Protein Alignment CG8468 and mct-6

DIOPT Version :10

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_510705.1
• Gene: mct-6 / 181724
• WormBaseID: WBGene00015676
• Length: 594
• Species: Caenorhabditis elegans
• Alignment Length: 679
• Identity: 203/679 - (29%)
• Similarity: 304/679 - (44%)
• Gaps: 164/679 - (24%)

  Fly    40 VVVPPDSGWAWVVMVASFLCCTVIDGIVFCSGLIQEQLMAEFGVSKAYVAFVSSLLSGCYLMAGP 104
            |.:|||.||.|||::.||......||.|:..|::.|.||.||..|....|.:.|||:|..|.:||
 Worm    14 VPLPPDGGWGWVVVLGSFFVHVFADGFVYSFGVLVETLMEEFHASNTMAALIISLLTGLTLGSGP 78

  Fly   105 FVSAMANRFGFRPVTITGAIFAAICFGLSYFATSVEYLFLIYGVLGGIGFCMVYIPAVVIIGFYF 169
            ..||:.|::|.|..|||||..|.:...||||||::.::.:..||:.|.||.::|.||:||:..||
 Worm    79 LASAVCNKYGCRITTITGAGVAFVGCALSYFATAMWHIVITVGVIMGTGFGLMYCPAIVIVTMYF 143

  Fly   170 EKWRALATGVAMCGSGVGTFVFAPLTKILLKS-GWRYT-LAIQGIIVLSCALFGLAFRPIQ---- 228
            |..|:||||:|:.|:||||.:|||:....:.: |||.. ||...|:|| |||.|..|.|::
 Worm   144 ENKRSLATGIAVAGAGVGTVLFAPINAFFINNYGWRSVFLAFLFILVL-CALCGATFAPLEFALV 207

  Fly   229 PITLSVTNEEGDEQEKKKL-----NGHGNTVAPTPQLHQAAFTKPLPEGRFAYSMPNSAHNTYMG 288
            |......|:|..:::.||.     :|...|:...|.|
 Worm   208 PDEEEEVNDEVLDEDVKKTAANEEHGEKATLLSPPSL---------------------------- 244

  Fly   289 ASQRNHYPTAQEIFKGMNLERRPSGTAQGSKGTELKQLRKSQPTTPNGDPQQLTFNLHKELTTVG 353
                              |||..|.::...|                                .|
 Worm   245 ------------------LERSMSQSSGVQK--------------------------------AG 259

  Fly   354 ENEEEAENDNLLETEAKPVTIQARRHTVSGRRPQDIGKRSAAAAHEAHHGQSHSSSRPMYRDDIF 418
            |....|.:...::.|::|   ::||.||..|                       .|..:.|.|:|
 Worm   260 EKIRPASSMGAVDVESQP---RSRRGTVGER-----------------------DSGYLNRKDVF 298

  Fly   419 FSGSLTRIPQ-------YQSQTSL-AYHMSVTRLPT-KQDMLEDRQKGCRICPEAVR-------- 466
            ::||::.:.:       |:|..|| ..|.:|..:|. ....|:|.::|.....:|:.
 Worm   299 YTGSISNVAEFREDPDKYRSTGSLHGRHTTVGSIPAHSTGRLDDVREGSEEDSKAMDISEKTNGT 363

  Fly   467 ------------RTLSTMLDTTLLKSPAFMCLAFSGFLTMMGFFVPFTFLVDRAKAAGMDEQAAY 519
                        :|:|.||...||..|.|:..|.|..||.:||..|..||...|...|::.....
 Worm   364 DNTDNVEGKNMFKTISNMLSLELLLEPTFLLFAISNLLTSVGFNSPLYFLPLHATKIGLEPIQGS 428

  Fly   520 GVLSGIGVVNTFARIVCGSLSSFPAVKP-----------LWLNNFALTAGGIATI-C---SGIVI 569
            .|||..||.||..||:.|.::......|           ||:.|.:||..|:.|: |   :|.:
 Worm   429 KVLSAFGVSNTVGRIIFGVVADHKLPLPGGIGNDTARNRLWMYNISLTICGLLTVFCYQFNGFI- 492

  Fly   570 NTATQWTFALFFGICIACFSALRSLIAVELIGLEKLTNAYGFLMLFQGLAATFGSPIAGGLYVMT 634
               ...|::..||..||.:..|.|:|.|:|:||:|||||:|.|:|:||:...||.|::|.|..||
 Worm   493 ---PLATYSALFGFSIASYICLTSVILVDLLGLDKLTNAFGLLLLWQGVGTVFGPPVSGYLADMT 554

  Fly   635 GSYNAAFYFAGGLILLSAFLCYPLTWVSR 663
            |:|..:|.|.|..:|.|..:.:.:.:..:
 Worm   555 GNYTLSFVFCGVNLLASGLMLFGIPFFQK 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS_MCT_SLC16	49..>225	CDD:340910	79/177 (45%)
		MFS	<477..658	CDD:475125	71/195 (36%)
mct-6	NP_510705.1	MFS_MCT_SLC16	23..579	CDD:340910	197/664 (30%)