Protein Alignment CG8468 and Mct1

DIOPT Version :10

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: XP_311120.3
• Gene: Mct1 / 1272237
• VectorBaseID: AGAMI1_011930
• Length: 606
• Species: Anopheles gambiae
• Alignment Length: 684
• Identity: 219/684 - (32%)
• Similarity: 325/684 - (47%)
• Gaps: 142/684 - (20%)

  Fly    26 KEENEGEEEIEEAAVVV-------PPDSGWAWVVMVASFLCCTVIDGIVFCSGLIQEQLMAEFGV 83
            :::.:.:.:||::...|       |||.||.|:|::|||....:.||:.:..|:...:.:..|..
Mosquito    11 RQQQQIDSDIEQSVTEVDPNGLPTPPDGGWGWMVVLASFSIHIITDGLTYSFGIFYSEFLTYFNE 75

  Fly    84 SKAYVAFVSSLLSGCYLMAGPFVSAMANRFGFRPVTITGAIFAAICFGLSYFATSVEYLFLIYGV 148
            .|.|.|:::|:|.|..|.:||..|::.||:|.|.|||.||:.|:....:|.:||||..||:..||
Mosquito    76 GKGYTAWIASILVGVTLCSGPISSSLVNRYGCRAVTIAGALLASASLAVSMYATSVFMLFITIGV 140

  Fly   149 LGGIGFCMVYIPAVVIIGFYFEKWRALATGVAMCGSGVGTFVFAPLTKILLKS-GWR-YTLAIQG 211
            ..|:|..::|:||:|.:..|||:.|:||||:|:||||:||.:|||||:.|:|. .|: ..|||.|
Mosquito   141 GTGLGLGLIYLPAIVSVTMYFERLRSLATGIAVCGSGLGTSIFAPLTEALIKKFQWQGALLAIAG 205

  Fly   212 IIVLSCALFGLAFRPI--QP-------------------ITLSVTNEEGDEQEKKKLNGHGNTVA 255
             |||.|.||||.|||:  :|                   .|:..|:...:|...|:.|.||:..|
Mosquito   206 -IVLICVLFGLMFRPLVHEPASPGKELQELPQHSSADPSTTMKPTSGNANESNLKRSNSHGHVDA 269

  Fly   256 PTPQLHQAAFTKPLPEGRFAYSMPNSAHNTYMGASQRNHYPTAQEIFKGMNLERRPSGTAQGSKG 320
            |...|:        ..|..|     |.||
Mosquito   270 PKIDLN--------ANGHSA-----SGHN------------------------------------ 285

  Fly   321 TELKQLRKSQPTTPNGDPQQLTFNLHKELTTVGENEEEAENDNLLETEAKPVTIQARRHTVSGRR 385
                 |.|...|||..|.::|  .|.:.|.|..|:             .:||.:   :.|.||
Mosquito   286 -----LDKHTRTTPGEDAKRL--GLSQPLLTAPES-------------VQPVPL---KRTESG-- 325

  Fly   386 PQDIGKRSAAAAHEAHHGQSHSSSRPMYRDDIFFSGSLTRI-PQYQSQTSLAYH----------M 439
                                     .|||.|..::||:..| .::.||.:|:.:          .
Mosquito   326 -------------------------TMYRKDALYTGSVHNIASRHASQANLSIYEKGSYGSVQGN 365

  Fly   440 SVTRLPTKQDMLEDRQKGCRICPEAVRRTLSTMLDTTLLKSPAFMCLAFSGFLTMMGFFVPFTFL 504
            .:.|.|.:.|..| |..||..|......|...|::.::||.|.|:....|.|||.:||.||:.:|
Mosquito   366 GLHRPPAEPDAPE-RCLGCIPCSRETCDTFREMMNFSILKDPIFIIFTVSNFLTSVGFNVPYVYL 429

  Fly   505 VDRAKAAGMDEQAAYGVLSGIGVVNTFARIVCGSLSSFPAVKPLWLNNFALTAGGIATICSGIVI 569
            ..:|:..|:..:.|..:|..||:.||..|||.|.||..|.|..|.:.|.:|...||||..|.:.:
Mosquito   430 AAQAQVLGIGSKDASYLLGIIGIANTVGRIVLGYLSDKPWVNRLAVYNCSLAVCGIATALSVLCV 494

  Fly   570 NTATQWTFALFFGICIACFSALRSLIAVELIGLEKLTNAYGFLMLFQGLAATFGSPIAGGLYVMT 634
            :......::..:|..|..:..|.|:|.|:|:||||||||:|.|:||||:|:..|.||||.||..|
Mosquito   495 DFYWLGVYSAVYGFTIGAYVGLTSVILVDLLGLEKLTNAFGLLLLFQGIASFVGPPIAGWLYDYT 559

  Fly   635 GSYNAAFYFAGGLILLSAFLCYPLTWVSRWEERR 668
            .||...|..||..|.:|..:.:.:..:.|:..||
Mosquito   560 LSYGPGFIMAGTTIAISGAMLFAIPSLQRYLARR 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS_MCT_SLC16	49..>225	CDD:340910	79/177 (45%)
		MFS	<477..658	CDD:475125	74/180 (41%)
Mct1	XP_311120.3	MFS_MCT_SLC16	41..584	CDD:340910	208/643 (32%)