Protein Alignment CG8468 and SLC16A10

DIOPT Version :10

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_061063.2
• Gene: SLC16A10 / 117247
• HGNCID: 17027
• Length: 515
• Species: Homo sapiens
• Alignment Length: 667
• Identity: 145/667 - (21%)
• Similarity: 221/667 - (33%)
• Gaps: 242/667 - (36%)

  Fly    23 ENIKEENEGEEEIEEAAVVVPPDSGWAWVVMVASFLCCTVIDGIVFCSGLIQEQLMAEFG----- 82
            |.::.|..|....|......||:.||.|:||:|:..|...:.||....|::...::..||
Human    44 EKVEVELAGPATAEPHEPPEPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDD 108

  Fly    83 --VSKAYVAFVSSLLSGCYLMAGPFVSAMANRFGFRPVTITGAIFAAICFGLSYFATSVEYLFLI 145
              |.|  .|:|.||..|......|.||...:.||.|...:.||....:....|.|.:|:|.|:|.
Human   109 KMVFK--TAWVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLT 171

  Fly   146 YGVLGGIGFCMVYIPAVVIIGFYFEKWRALATGVAMCGSGVGTFVFAPLTKILLKS-GWRYTLAI 209
            ||::...|....|.|::||:|.||:|...|..|:...||.|.|.:...|.::|:.| |..|||.:
Human   172 YGIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRV 236

  Fly   210 QGIIVLSCALFGLAFRPIQPITLSVTNEEGDEQEKKKLNGHGNTVAPTPQLHQAAFTKPLPEGRF 274
            ..|.:....|.|..:||:...|           :.|:..|.|:::.                .|.
Human   237 LCIFMFVLFLAGFTYRPLATST-----------KDKESGGSGSSLF----------------SRK 274

  Fly   275 AYSMPNSAHNTYMGASQRNHYPTAQEIFKGMNLERRPSGTAQGSKGTELKQLRKSQPTTPNGDPQ 339
            .:|.|....|.              .|||
Human   275 KFSPPKKIFNF--------------AIFK------------------------------------ 289

  Fly   340 QLTFNLHKELTTVGENEEEAENDNLLETEAKPVTIQARRHTVSGRRPQDIGKRSAAAAHEAHHGQ 404
                                            ||
Human   290 --------------------------------VT------------------------------- 291

  Fly   405 SHSSSRPMYRDDIFFSGSLTRIPQYQSQTSLAYHMSVTRLPTKQDMLEDRQKGCRICPEAVRRTL 469
                                           ||.:....:|
Human   292 -------------------------------AYAVWAVGIP------------------------ 301

  Fly   470 STMLDTTLLKSPAFMCLAFSGFLTMMGFFVPFTFLVDRAKAAGMDEQAAYGVLSGIGVVNTFARI 534
                                  |.:.|:|||:..|:........||:....||..|||.:...|:
Human   302 ----------------------LALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRL 344

  Fly   535 VCGSLSSF-PAVKPLWLNNFALTAGGIAT----ICS--GIVINTATQWTFALFFGICIACFSALR 592
            :.|.::.: |.||.::|...:....|:.:    :||  |.:|      ...|..|:...||.::.
Human   345 LFGRIADYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALI------AVCLIMGLFDGCFISIM 403

  Fly   593 SLIAVELIGLEKLTNAYGFLMLFQGLAATFGSPIAGGLYVMTGSYNAAFYFAGGLILL-SAFLCY 656
            :.||.||:|.:.::.|.|||:.|..:..|.|.||||.|....|||:.|||.||...|: .|.||:
Human   404 APIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCF 468

  Fly   657 PLTWVSRWEERRNEKLT 673
             :.|:...::|...|.|
Human   469 -IPWIHSKKQREISKTT 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS_MCT_SLC16	49..>225	CDD:340910	58/183 (32%)
		MFS	<477..658	CDD:475125	57/188 (30%)
SLC16A10	NP_061063.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..48		1/3 (33%)
		MFS_MCT10	70..470	CDD:341022	133/625 (21%)