DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sox15 and SOX14

DIOPT Version :9

Sequence 1:NP_523739.2 Gene:Sox15 / 36575 FlyBaseID:FBgn0005613 Length:784 Species:Drosophila melanogaster
Sequence 2:NP_004180.1 Gene:SOX14 / 8403 HGNCID:11193 Length:240 Species:Homo sapiens


Alignment Length:239 Identity:71/239 - (29%)
Similarity:109/239 - (45%) Gaps:68/239 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   209 SAKESRIRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQDRRPYVEEAERLRV 273
            |.....|:|||||||||::.:|:|:|.|||.:||:::||.||.:|:.|:..::|||::||:|||.
Human     2 SKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRA 66

  Fly   274 IHMTEHPNYKYRPRRRKQSKLR--------------------AMQPGGKEQSESSP--------- 309
            .||.|||:|||||||:.::.|:                    .:..|..:...|:|         
Human    67 QHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPYLGDTDPLKAAGLPVGASDGLLSAPEKARAFLPP 131

  Fly   310 --------NPGTGGSKSNPKLATPP--LATASSSYT------------------------TPTDE 340
                    :|....|.:..|:...|  |||.:..|.                        :||:.
Human   132 ASAPYSLLDPAQFSSSAIQKMGEVPHTLATGALPYASTLGYQNGAFGSLSCPSQHTHTHPSPTNP 196

  Fly   341 S---TCNSTNQNHGQSTPGGLYEQPLKPTYSPSSVDCYSNADST 381
            .   .||.|..:.....|...|  .|.|..:.:.:|.||:|.:|
Human   197 GYVVPCNCTAWSASTLQPPVAY--ILFPGMTKTGIDPYSSAHAT 238

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sox15NP_523739.2 SOX-TCF_HMG-box 214..285 CDD:238684 39/70 (56%)
SOX14NP_004180.1 SOX-TCF_HMG-box 7..78 CDD:238684 39/70 (56%)
SOXp 77..>118 CDD:403523 7/40 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0527
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000028
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10270
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R685
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
54.940

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